dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice

Published 2019 View Full Article

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Title
dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice
Authors
Keywords
gene therapy, Dravet syndrome, epileptic encephalopathy, activatory CRISPR
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2019-09-04
DOI
10.1016/j.ymthe.2019.08.018

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