lnc RNA ‐ PDPK 2P promotes hepatocellular carcinoma progression through the PDK 1/ AKT /Caspase 3 pathway

Toll-like receptor 5 signaling restrains T-cell/natural killer T-cell activation and protects against concanavalin A-induced hepatic injury

(2017) Lei Wang et al.   HEPATOLOGY

Multilineage communication regulates human liver bud development from pluripotency

(2017) J. Gray Camp et al.   NATURE

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition

(2016) Pau Castel et al.   CANCER CELL

A long noncoding RNA in DNA replication and chromosome dynamics

(2016) Francesco P. Marchese et al.   CELL CYCLE

Association of Hepatitis B Virus Covalently Closed Circular DNA and Human APOBEC3B in Hepatitis B Virus-Related Hepatocellular Carcinoma

(2016) Xuan Luo et al.   PLoS One

PTEN ceRNA networks in human cancer

(2015) Laura Poliseno et al.   METHODS

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

Curcumin ameliorate DENA-induced HCC via modulating TGF-β, AKT, and caspase-3 expression in experimental rat model

(2014) Mekky M. M. Abouzied et al.   TUMOR BIOLOGY

Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

(2013) Stefan Eser et al.   CANCER CELL

Inflammation in background cirrhosis evokes malignant progression in HCC development from HCV-associated liver cirrhosis

(2013) Kazuo Tarao et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomy

(2012) Sheng-Xian Yuan et al.   HEPATOLOGY

Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin

(2012) Jin-feng Huang et al.   HEPATOLOGY

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

(2011) Jian-Hong Fang et al.   HEPATOLOGY

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome–like skeletal defects induced by Pdk1 or Cbp mutations in mice

(2011) Jae-Hyuck Shim et al.   JOURNAL OF CLINICAL INVESTIGATION

Pseudogene-derived small interference RNAs regulate gene expression in African Trypanosoma brucei

(2011) Y.-Z. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcribed dark matter: meaning or myth?

(2010) C. P. Ponting et al.   HUMAN MOLECULAR GENETICS

3-Phosphoinositide-Dependent Protein Kinase-1 Regulates Proliferation and Survival of Cancer Cells with an Activated Mitogen-Activated Protein Kinase Pathway

(2010) Z. Lu et al.   MOLECULAR CANCER RESEARCH

Hepatitis B and C virus-related carcinogenesis

(2009) J. Fung et al.   CLINICAL MICROBIOLOGY AND INFECTION

The survival pathways phosphatidylinositol-3 kinase (PI3-K)/phosphoinositide-dependent protein kinase 1 (PDK1)/Akt modulate liver regeneration through hepatocyte size rather than proliferation

(2008) Sanae Haga et al.   HEPATOLOGY

In VivoAnalysis of Protein Kinase B (PKB)/Akt Regulation in DNA-PKcs-null Mice Reveals a Role for PKB/Akt in DNA Damage Response and Tumorigenesis

(2008) Banu Surucu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuning in to the signals: noncoding sequence conservation in vertebrate genomes

(2008) Greg Elgar et al.   TRENDS IN GENETICS