Multidimensional Proteomics Identifies Declines in Protein Homeostasis and Mitochondria as Early Signals for Normal Aging and Age-associated Disease in Drosophila

Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila

(2018) Zaijun Ma et al.   eLife

Changes of Protein Turnover in AgingCaenorhabditis elegans

(2017) Ineke Dhondt et al.   MOLECULAR & CELLULAR PROTEOMICS

Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective

(2016) Alessandra Valerio et al.   Aging-US

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Monitoring Newly Synthesized Proteins over the Adult Life Span of Caenorhabditis elegans

(2015) Krishna Vukoti et al.   JOURNAL OF PROTEOME RESEARCH

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

(2015) Johannes Mansfeld et al.   Nature Communications

COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems

(2014) Yasunobu Okamura et al.   NUCLEIC ACIDS RESEARCH

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Cardiac Care for Older Adults

(2011) Daniel E. Forman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The dynamic state of protein turnover: It's about time

(2011) Izumi V. Hinkson et al.   TRENDS IN CELL BIOLOGY

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice

(2010) Giuseppe D'Antona et al.   Cell Metabolism

Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging

(2010) Dirk M. Walther et al.   MOLECULAR & CELLULAR PROTEOMICS

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

bioDBnet: the biological database network

(2009) Uma Mudunuri et al.   BIOINFORMATICS

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Impact of aging on the biology of breast cancer

(2007) Christopher C. Benz   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY