Computational biomedical simulations of hybrid nanoparticles on unsteady blood hemodynamics in a stenotic artery

In this paper, hybrid nano-particle (Ag, Al2O3) model is implemented in the time dependent blood flow equations in order to investigate its effects on the flow pattern of blood particles. The two directional momentum equations are normalized and reduced to the uni-directional flow by using the mild stenotic supposition. The couple partial differential equations are discretized by using finite difference technique. A computer code is developed, using Matlab, in order to solve these algebraic equations. Consequently, these solutions are used to explore the effects of nanoparticles (silver Ag) as well as hybrid nanoparticles (Ag-Al2O3/blood) on the blood flow parameters such as velocity, flow rate, wall shear stress and streamlines. Furthermore, a comparison has been made between the results of hybrid nanoparticles (Ag-Al2O3/blood) and silver (Ag) nanoparticles and this comparison instigates that the hybrid nanoparticles (Ag-Al2O3/blood) are more helpful in attenuating the hemodynamics factors (such as wall shear stress and impedance) as compared to the silver (Ag) nanoparticles. Moreover, the results for the different values of source/sink parameter have also been calculated and it also displays that these parameters play an important role in attenuating the hemodynamics factors (such as wall shear stress and resistance to flow or impedance). The overall global behavior of the blood flow patterns is also perceived through the streamlines for different emerging parameters. (C) 2019 International Association for Mathematics and Computers in Simulation (IMACS). Published by Elsevier B.V. All rights reserved.