Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction

Title
Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction
Authors
Keywords
Camptothecin, C-20 position, Cytotoxic activity, Poly(ethylene glycol) (PEG), Sulfonylamidine
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 25, Issue 13, Pages 2690-2693
Publisher
Elsevier BV
Online
2015-05-06
DOI
10.1016/j.bmcl.2015.04.060

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