Role of Asparagine Endopeptidase in Mediating Wild-Type p53 Inactivation of Glioblastoma

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

(2018) Robert J. Ihry et al.   NATURE MEDICINE

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

(2018) Emma Haapaniemi et al.   NATURE MEDICINE

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

(2018) Chaido Stathopoulou et al.   IMMUNITY

Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival

(2017) Youn-Jung Kang et al.   Nature Communications

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Structure and function of legumain in health and disease

(2016) Elfriede Dall et al.   BIOCHIMIE

A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas

(2016) Alice Soragni et al.   CANCER CELL

Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo

(2016) E P Erkan et al.   CANCER GENE THERAPY

Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention

(2016) F Wendler et al.   ONCOGENE

Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma

(2015) L Treps et al.   ONCOGENE

Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage

(2014) Lixia Zhao et al.   CELL RESEARCH

The cytoplasmic side of p53's oncosuppressive activities

(2014) Anna Comel et al.   FEBS LETTERS

Functional Role of Asparaginyl Endopeptidase Ubiquitination by TRAF6 in Tumor Invasion and Metastasis

(2014) Yingying Lin et al.   JNCI-Journal of the National Cancer Institute

Role of glycosyltransferase PomGnT1 in glioblastoma progression

(2014) J. Lan et al.   NEURO-ONCOLOGY

Microvesicles as a Biomarker for Tumor Progression versus Treatment Effect in Radiation/Temozolomide-Treated Glioblastoma Patients

(2014) Cameron J. Koch et al.   Translational Oncology

Transcriptional regulation of the legumain gene by p53 in HCT116 cells

(2013) Takuya Yamane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Asparagine endopeptidase is required for normal kidney physiology and homeostasis

(2011) Gail Miller et al.   FASEB JOURNAL

Nucleoplasmic calcium regulates cell proliferation through legumain

(2011) Viviane Andrade et al.   JOURNAL OF HEPATOLOGY

Rapid and Robust Transgenic High-Grade Glioma Mouse Models for Therapy Intervention Studies

(2010) N. A. de Vries et al.   CLINICAL CANCER RESEARCH

Role of calpain-mediated p53 truncation in semaphorin 3A-induced axonal growth regulation

(2010) Q. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

87 Nucleoplasmic Calcium Regulates Proliferation of Hepatocytes Through Legumain and Reticulon4

(2009) Viviane A. Andrade et al.   GASTROENTEROLOGY

Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells

(2009) Fernando E. Sepulveda et al.   IMMUNITY

Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

(2008) Valerie Clerin et al.   ATHEROSCLEROSIS

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase

(2008) Zhixue Liu et al.   MOLECULAR CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY