Editorial Material
Obstetrics & Gynecology
Julia Pakey, Janelle S. Nassim, Rachel Reynolds
Summary: Counseling patients about the risk of acne associated with hormonal intrauterine devices is crucial in shared decision making for contraception methods.
OBSTETRICS AND GYNECOLOGY
(2022)
Review
Psychology, Clinical
Katherine Ogle, Ariel B. B. Handy
Summary: The aims of this review were to analyze the impact of copper (Cu) and levonorgestrel (LNG) intrauterine devices (IUDs) on female sexual function. A total of 35 quantitative and 2 qualitative research papers were included in this review. The findings suggest that LNG-IUDs have a positive effect on sexual pain and a positive-to-neutral effect on sexual desire, while the impact on other domains of sexual function is generally non-significant.
INTERNATIONAL JOURNAL OF SEXUAL HEALTH
(2023)
Article
Psychology, Clinical
Juliana E. French, Anastasia Makhanova, Andrea L. Meltzer
Summary: This study examines the impact of childhood ecologies on people's sexual desire and finds that the unpredictability of childhood ecologies is positively associated with dyadic sexual desire among naturally cycling females. These findings suggest that the instability of early childhood ecologies can adaptively calibrate adult reproductive motivations and behaviors.
ARCHIVES OF SEXUAL BEHAVIOR
(2023)
Article
Oncology
Lisa Iversen, Shona Fielding, Ojvind Lidegaard, Philip C. Hannaford
Summary: The study found that the use of any hormonal contraceptives increases the risk of cervical cancer, especially in current or recent users. The risk is higher with combined contraceptives compared to progestin-only contraceptives, affecting both adenocarcinoma and squamous cancer.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Review
Obstetrics & Gynecology
S. A. Kingsberg, B. Adler, J. Metropoulos, S. S. Faubion
Summary: Numerous surveys have indicated that sexuality and/or sexual activity is important to women at all stages of adulthood, including postmenopause. Postmenopausal women commonly experience genitourinary syndrome of menopause (GSM) and hypoactive sexual desire disorder (HSDD), both of which may be undiagnosed due to various reasons. Health-care professionals have a responsibility to identify and differentiate these conditions through a comprehensive assessment and may need to perform a focused physical examination. There are numerous treatment options, both non-pharmacologic and pharmacologic, available for GSM and HSDD.
Article
Medicine, General & Internal
Fatima Leon-Larios, Jose Gutierrez Ales, Maria Jose Puente Martinez, Marta Correa Rancel, Isabel Lahoz Pascual, Isabel Silva Reus, Jose Cruz Quilez Conde
Summary: The National Contraception Survey conducted in Spain aimed to understand the sexual and contraceptive habits of Spanish women of reproductive age. The results indicate that condoms and oral contraceptives are the most frequently used methods, but the use of Long-acting Reversible Contraceptives is still low. Counselling on contraception is mainly provided by gynecologists, and the recommendations of health professionals have a strong influence on the choice of contraceptive methods.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Andreia Gomes Bezerra, Monica Levy Andersen, Gabriel Natan Pires, Sergio Tufik, Helena Hachul
Summary: The effects of hormonal contraceptives on sleep are contradictory, but this systematic review and meta-analysis concluded that they are not associated with clinically relevant changes in sleep patterns in women.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Ana Luiza Vilela Borges, Christiane Borges do Nascimento Chofakian, Osmara Alves Viana, Eveline do Amor Divino
Summary: The study aimed to estimate the total contraceptive discontinuity rates in the use of oral and injectable hormonal contraceptives, and male condoms, as well as dropout rates due to switches to more effective and less effective methods. The results showed high contraceptive discontinuity rates with varied reasons, with about half of the users switching to other methods after 12 months.
CADERNOS DE SAUDE PUBLICA
(2021)
Article
Obstetrics & Gynecology
Mariana Ramos-Rivera, Sarah Averbach, Praveena Selvaduray, Amanda Gibson, Lynn L. Ngo
Summary: This study evaluated the rates of uterine perforation and expulsion with intrauterine device (IUD) placement at 4-8 weeks postpartum versus 9-36 weeks postpartum. The results showed that the rate of uterine perforation was significantly higher with IUD placement at 4-8 weeks compared to 9-36 weeks. However, there was no difference in expulsion rates between the two groups. Therefore, women can safely choose IUDs at any interval beyond 4 weeks with minimal concern for perforation.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Sara Hogmark, Karin Lichtenstein Liljeblad, Niklas Envall, Kristina Gemzell-Danielsson, Helena Kopp Kallner
Summary: This study aimed to investigate if placement of an intrauterine device within 48 hours of completed medical abortion at up to 63 days' gestation leads to higher user rates at 6 months after the abortion compared with placement at 2 to 4 weeks after abortion. The results showed that there was no significant difference in usage rates between the intervention group and the control group. Furthermore, early placement of intrauterine devices seems to be safe, preferred by patients, and associated with lower pain scores.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Psychology, Clinical
J. Michael Bailey, Ray Blanchard, Kevin J. Hsu, William Revelle
Summary: Men's sexual interest in adults and children is influenced by the targets' sexual maturity and biological sex, which are predictive of sexual offending. Men's preferences for prepubescent children compared to adults of their preferred sex are significant.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Ella F. Eastin, Alan Nelson, Jonathan G. Shaw, Kate A. Shaw, Lianne M. Kurina
Summary: This study investigated the use of postpartum long-acting reversible contraception among active-duty female soldiers and found relatively low rates of use. Even among a population with universal healthcare coverage, significant disparities in the uptake of effective postpartum long-acting contraceptive methods were observed across different racial categories.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Physiology
Valerie Bougault, Sandrine Schiano-Lomoriello, Carole Castanier, Corinne Buisson, Magnus Ericsson, Caroline Teulier, Katia Collomp
Summary: The aim of this study was to examine the association between physical activity and combined hormonal contraception on female students' self perception of menstrual cycle symptoms. The study found that female students engaging in high intensity physical activity reported fewer perceived symptoms and this effect was more pronounced when combined with the use of CHC. Additionally, female students engaging in high intensity physical activity also reported less university absenteeism and impairment in physical activities.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Immunology
Kathryn Peebles, Flavia M. Kiweewa, Thesla Palanee-Phillips, Catherine Chappell, Devika Singh, Katherine E. Bunge, Logashvari Naidoo, Bonus Makanani, Nitesha Jeenarain, Doerieyah Reynolds, Sharon L. Hillier, Elizabeth R. Brown, Jared M. Baeten, Jennifer E. Balkus
Summary: The study suggests that Cu-IUD users have a higher risk of BV, which persists throughout use. Women and their providers may need to consider this risk when discussing contraceptive options.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Clinical Neurology
Pelin Batur, Meng Yao, Julia Bucklan, Payal Soni, Aarushi Suneja, Ruth Farrell, Maryann Mays
Summary: This study aims to investigate the impact of factors such as estrogen dose and migraine history on ischemic stroke risks associated with using combined hormonal contraceptive (CHC). The use of CHC has been restricted in individuals with migraine with aura due to concerns about stroke risk.
Article
Urology & Nephrology
David W. Barham, Irene K. Chen, Aubrey Reeves, Eric Chung, Yacov Reisman, Martin S. Gross, Faysal A. Yafi
Summary: The objective of this study was to characterize the standard perioperative practices of penile prosthetic surgeons. A survey was conducted among prosthetic urologists to assess their preoperative and postoperative evaluation methods. The findings suggest that while most surgeons pay attention to grip strength and patient expectations before surgery, there is a lack of consistency in assessing sexual orientation, intended use of the implant, sexual activity, and partner satisfaction. The study highlights the need for improvement in these areas.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
(2023)
Article
Clinical Neurology
Josh E. Schroeder, Tal Michaeli, Mijal Luria, Eyal Itshayek, Leon Kaplan
Summary: This study is a retrospective cohort study that evaluates sexual function and experience in adult women who underwent scoliotic correction for adolescent idiopathic scoliosis (AIS). The results show that there are long-term consequences in terms of sexual distress and dysfunction after surgery or bracing treatment for AIS.
GLOBAL SPINE JOURNAL
(2023)
Editorial Material
Psychiatry
M. I. C. H. A. L. LEW-STAROWICZ, E. L. COLEMAN
Summary: After the introduction of compulsive sexual behavior disorder (CSBD) in the ICD-11, there are still many unanswered questions regarding its etiology, classification, and diagnostic criteria. This commentary critically reviews the ongoing discussion and highlights the risks of oversimplification, as well as the neglected aspects such as psychosexual development, intimacy disorder, and the role of sexological expertise in assessment and treatment. The authors advocate for a multimodal, transtheoretical approach and suggest reconsidering CSBD as a condition related to sexual health.
JOURNAL OF BEHAVIORAL ADDICTIONS
(2022)
Editorial Material
Psychiatry
Michal Lew-Starowicz, Malgorzata Draps, Ewelina Kowalewska, Katarzyna Obarska, Shane W. Kraus, Mateusz Gola
Article
Andrology
Arcangelo Barbonetti, Giulia Rastrelli, Clotilde Sparano, Chiara Castellini, Linda Vignozzi, Mario Maggi, Giovanni Corona
Summary: A study found that male cannabis users are younger, have fewer comorbidities, and have better sexual performance compared to non-users. Cannabis use is associated with a more unstable relationship and a higher frequency of masturbation. Cannabis use may improve anthropometric and lipid profiles as well as penile arterial response in patients with sexual dysfunction.
Article
Andrology
Dimitri Yannas, Elena Zago, Elena Cavallini, Tommaso Todisco, Linda Vignozzi, Giovanni Corona, Mario Maggi, Giulia Rastrelli
Summary: This study found that the level of education is closely associated with erectile dysfunction and cardiovascular risk in men. Men with lower education level are more likely to have erectile dysfunction and metabolic syndrome, as well as a higher risk of cardiovascular events.
Review
Urology & Nephrology
G. Corona, G. Rastrelli, N. Bianchi, C. Sparano, A. Sforza, L. Vignozzi, M. Maggi
Summary: The present paper aims to analyze and discuss the relationship between male sexual function and elevated prolactin (PRL) levels (HPRL) using clinical data and meta-analytic approach. 4.2% of patients seeking medical care for sexual dysfunction showed PRL levels above the normal range. HPRL was found to have a negative influence on male sexual desire. Treating HPRL can improve libido, but its effect on erection is limited. The role of HPRL in erectile dysfunction remains inconclusive. Overall, the paper provides important evidence on the relationship between PRL levels and male sexual function.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Lara Tamburrino, Giulia Traini, Arianna Marcellini, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani
Summary: Cryopreservation is an expanding strategy for fertility preservation, animal breeding, and endangered species preservation. Despite improvements in semen cryopreservation techniques, damage to spermatozoa and its impairment of function remain unsolved problems. Active research is needed to optimize the cryopreservation process and prevent sperm damage. This review discusses the evidence of structural, molecular, and functional damage in cryopreserved human spermatozoa and strategies to prevent it, as well as the outcomes of assisted reproduction techniques using cryopreserved spermatozoa.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Federica Riva, Nora Bloise, Claudia Omes, Gabriele Ceccarelli, Lorenzo Fassina, Rossella Elena Nappi, Livia Visai
Summary: Recent studies have found stem cells (hFF-MSCs) in ovarian follicular fluid (hFF) with similar properties to MSCs derived from other tissues. These hFF-MSCs, isolated from waste matter after oocyte retrieval, are an untapped source of stem cell materials. This study evaluates the osteogenic capacity of hFF-MSCs seeded on bioglass 58S-coated titanium and their suitability for bone tissue engineering. The findings suggest that hFF-MSCs cultured on bioglass-coated titanium exhibit enhanced osteogenic differentiation, indicating their potential in regenerative medicine and as an alternative to hBM-MSCs in bone tissue engineering models.
Article
Biochemistry & Molecular Biology
Costanza Calamai, Oumaima Ammar, Viktoria Rosta, Ginevra Farnetani, Salvatore Zimmitti, Lisa Giovannelli, Linda Vignozzi, Csilla Krausz, Monica Muratori
Summary: Cancer significantly increases sperm DNA fragmentation (sDF) and oxidative stress levels. The induction of viable oxidative stress is even higher in cancer patients compared to normozoospermic subfertile patients and healthy donors. There is a correlation between sDF and viable oxidative stress in all subjects, but not in cancer patients alone. Detecting oxidative stress could help manage the reproductive issues of cancer patients.
Review
Urology & Nephrology
Herman H. J. Leliefeld, Frans M. J. Debruyne, Yakov Reisman
Summary: Finasteride and dutasteride, 5α-reductase inhibitors, are commonly used for benign prostatic hyperplasia/lower urinary tract symptoms and alopecia, but have various side effects. These side effects include sexual dysfunction, neurological disorders, psychiatric disorders, endocrine disorders, metabolic disorders, and ophthalmological dysfunctions, as well as an increased risk of high-grade prostate cancer. The drugs can also cause persistent sexual side effects in a small subgroup of patients after discontinuation, known as post-finasteride syndrome. Further research and therapeutic innovations are needed to address these side effects, and physicians need to be more aware of the potential risks.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Giulia Traini, Lara Tamburrino, Maria Emanuela Ragosta, Giulia Guarnieri, Annamaria Morelli, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani
Summary: Benzo(a)pyrene (BaP) is a dangerous air pollutant that can have adverse effects on human spermatozoa, including reproductive toxicity. In vitro experiments showed that BaP reduced sperm motility and migration, increased spontaneous acrosome reaction and DNA fragmentation, but had no effects on apoptotic pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Andrology
Sara Dabizzi, Costanza Calamai, Selene Degl'Innocenti, Luca Boni, Linda Vignozzi, Mario Maggi, Elisabetta Baldi, Monica Muratori
Summary: In this pilot study, researchers investigated the recoveries of sperm motility and viability in severe oligozoospermic subjects after cryopreservation using a tip-microVapour Fast Freezing procedure. The results showed that the tip-microVapour Fast Freezing method had better outcomes in terms of sperm parameters compared to the conventional Vapour Fast Freezing method with larger straws.
Article
Medicine, General & Internal
Sara Marchiani, Selene Degl'Innocenti, Sara Dabizzi, Lara Tamburrino, Maria Grazia Fino, Giulia Traini, Costanza Calamai, Mario Maggi, Linda Vignozzi, Elisabetta Baldi, Francesco Lotti
Summary: Sperm cryopreservation is recommended for male fertility preservation in cancer patients or other medical conditions. The recovery rates of motility and viability vary depending on the medical condition. Our study showed that lower sperm quality led to lower recovery rates, and donor samples had the highest recovery rates. Cut-off values for motility recovery were established based on initial semen quality. Overall, our results emphasize the importance of considering intrinsic sperm characteristics in cryopreservation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Letter
Immunology
Matteo Marconi, Gloria Riitano, Alessandra Daphne Fisher, Carlotta Cocchetti, Maria Teresa Pagano, Antonella Capozzi, Agostina Longo, Sara D'Arienzo, Linda Vignozzi, Maurizio Sorice, Elena Ortona, Marina Pierdominici
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
(2023)