Article
Clinical Neurology
Fei Xie, LinLin Zhou, Qiang Hu, LingYun Zeng, YanYan Wei, XiaoChen Tang, YuQing Gao, YeGang Hu, LiHua Xu, Tao Chen, HaiChun Liu, JiJun Wang, Zheng Lu, YingYao Chen, TianHong Zhang
Summary: This study found that cardiac autonomic function can be used to differentiate between unipolar depression, bipolar depression, and bipolar mania patients. Patients with bipolar depression had a greater extent of cardiac imbalance compared to those with unipolar depression. The area under the receiver operating characteristic curve for cardiac variables can be used for the diagnosis of different mental disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Multidisciplinary Sciences
Laurie Thiesse, Luc Staner, Patrice Bourgin, Henri Comtet, Gil Fuchs, Debora Kirscher, Thomas Roth, Jean Yves Schaffhauser, Jay B. Saoud, Antoine U. Viola
Summary: Polysomnographic sleep architecture parameters are commonly used in the diagnosis and treatment of sleep disorders. This paper evaluates the performance of Somno-Art Software in detecting sleep parameter differences between patients with sleep disorders and healthy subjects. The results show that Somno-Art provides comparable results to polysomnography, making it a useful tool for diagnosis and treatment follow-up.
Article
Nutrition & Dietetics
Yu-Ting Ho, Ying-Chieh Tsai, Terry B. J. Kuo, Cheryl C. H. Yang
Summary: This study found that PS128 can improve depressive symptoms, fatigue levels, brainwave activity, and awakenings during deep sleep, with changes related to brain waves and sleep maintenance. Daily intake of PS128 may help improve depressive symptoms and sleep quality in insomniacs.
Review
Clinical Neurology
Arron T. L. Correia, Gosia Lipinska, H. G. Laurie Rauch, Philippa E. Forshaw, Laura C. Roden, Dale E. Rae
Summary: There is a bidirectional relationship between poor sleep and mood-and anxiety-related disorders, and both are independently associated with altered autonomic nervous system (ANS) function. Heart rate variability (HRV) can reflect ANS dysregulation during sleep, which may play a mediating role in the association between poor sleep and mood-and anxiety-related disorders.
Article
Agriculture, Dairy & Animal Science
Laura B. Hunter, Marie J. Haskell, Fritha M. Langford, Cheryl O'Connor, James R. Webster, Kevin J. Stafford
Summary: Research suggests that heart rate and heart rate variability in cows change with sleep stages, indicating they could be a promising alternative method to assess sleep in dairy cows. These measures could provide valuable insights into the effects of stress or environmental changes on cow welfare.
Article
Clinical Neurology
Lara Rosler, Glenn van der Lande, Jeanne Leerssen, Austin G. Vandegriffe, Oti Lakbila-Kamal, Jessica C. Foster-Dingley, Anne C. W. Albers, Eus J. W. van Someren
Summary: This study evaluates the objective quantification of insomnia by assessing state-related changes in cardiac measures. The researchers found that incorporating these changes in cardiac features in the ambulatory monitoring of sleep could provide a more sensitive biomarker for diagnosing and assessing the severity of insomnia.
Article
Psychology, Biological
Shanshan Lin, Yiwei Du, Yujie Xia, Ling Xiao, Gaohua Wang
Summary: This study investigated the changes in sleep quality, heart rate variability (HRV), and resting-state electroencephalogram (rsEEG) in major depressive disorder (MDD) patients, and explored the use of HRV and rsEEG as convenient tools to assess sleep quality in MDD patients. The results showed that MDD patients had higher PSQI scores and lower levels of HRV compared to healthy controls. Sleep latency was negatively correlated with RMSSD and HF, and delta, theta, and alpha band power of rsEEG were higher in MDD patients. Regression analysis indicated that delta band power of TP8, as well as theta and alpha band power of AF3, could predict PSQI score in MDD patients.
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2023)
Article
Medicine, Research & Experimental
Chun-Ting Lai, Chun-Yu Chen, Sheng-Chieh She, Wei-Jen Chen, Terry B. J. Kuo, Hui-Ching Lin, Cheryl C. H. Yang
Summary: The study demonstrated that Lactobacillus brevis ProGA28 can alleviate stress-related sleep disturbances by increasing parasympathetic activity and reducing anxiety-like behaviors.
Article
Pediatrics
Robert L. Myette, Janusz Feber, Henrietta Blinder, Glenda N. Bendiak, Bethany J. Foster, Joanna E. MacLean, Evelyn Constantin, Sherri L. Katz
Summary: This study analyzed the improvement of blood pressure variability in obese youth with sleep-disordered breathing after positive airway pressure treatment, showing significant decreases in nighttime blood pressure. The findings suggest that positive airway pressure treatment can lead to a clinically significant improvement in sympathetic nerve activity in youth with obesity and sleep-disordered breathing.
PEDIATRIC RESEARCH
(2022)
Article
Clinical Neurology
Beatrice R. Benjamin, Mathias Valstad, Torbjorn Elvsashagen, Erik G. Jonsson, Torgeir Moberget, Adriano Winterton, Marit Haram, Margrethe C. Hoegh, Trine Lagerberg, Nils Eiel Steen, Lars Larsen, Ole A. Andreassen, Lars T. Westlye, Daniel S. Quintana
Summary: Heart rate variability was significantly decreased in patients with schizophrenia and bipolar disorder, and was associated with disease severity, potentially serving as a biomarker for disease severity in SZ and BD.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Gavin Brupbacher, Thea Zander-Schellenberg, Doris Straus, Hildburg Porschke, Denis Infanger, Markus Gerber, Roland von Kanel, Arno Schmidt-Trucksass
Summary: This study aimed to quantify the effect of a single bout of aerobic exercise on nocturnal heart rate variability and pre-sleep arousal in patients with unipolar depression. The findings did not show a significant impact of the exercise intervention on sleep quality and depressive symptoms. Further research is needed to confirm these results and explore the potential benefits of regular exercise for patients with depression.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Anton R. Kiselev, Oxana M. Drapkina, Mikhail Yu. Novikov, Olga S. Panina, Yuri V. Chernenkov, Maksim O. Zhuravlev, Anastasiya E. Runnova
Summary: Early age-related changes in EEG time-frequency characteristics during newborns' restful sleep contribute to the development of conventional EEG signs of deep sleep within the first week of postnatal life. Grouping newborns based on their gestational age and postnatal period reveals significant intergroup differences in brain activity during sleep and wakefulness, as well as considerable variability in the time-frequency characteristics of brain activity. The development of conventional deep sleep in infants born before 35 weeks of gestation is associated with an increase in alpha activity power in the sensorimotor cortex of the brain.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Vivien Tomacsek, Borbala Blaskovich, Anna Kiraly, Richard Reichardt, Peter Simor
Summary: Nightmare disorder is characterized by dysfunctional emotion regulation and poor sleep quality, including abnormal arousal processes and sympathetic influences. This study aimed to investigate the cardiac variability of frequent nightmare recallers (NMs) compared to healthy controls (CTL) during sleep, pre-sleep wakefulness, and an emotion-evoking picture-rating task. The results showed autonomic dysregulation during sleep in NMs, with no significant differences in cardiac variability between the two groups. However, NMs exhibited increased heart rate (HR) and reduced HRV during the emotion-evoking picture-rating task, indicating disrupted emotion regulation under acute distress.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Engineering, Civil
Anna Persson, Hanna Jonasson, Ingemar Fredriksson, Urban Wiklund, Christer Ahlstrom
Summary: The study investigates the reliability of HRV as a standalone feature for driver sleepiness detection in a realistic setting, using data from three real-road driving studies. The results show that in realistic driving conditions, subject-independent sleepiness classification based on HRV is poor, indicating a need for further research to control for other influencing factors.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2021)
Article
Clinical Neurology
Emily Charlotte Stanyer, Hannah Creeney, Alexander David Nesbitt, Philip Robert Holland, Jan Hoffmann
Summary: The meta-analysis revealed that individuals with migraine experience poorer subjective sleep quality and altered sleep architecture compared to healthy controls. Both adult and pediatric patients with migraine showed differences in various sleep parameters when compared to controls. More longitudinal empirical studies are needed to further understand this relationship.
Article
Psychiatry
Jeremiah Ayalde, Deborah Wearne, Sean Hood, Flavie Waters
Summary: This study aims to increase awareness among clinicians and researchers about distinguishing between visual hallucinations and trauma-related visual re-experiencing phenomena. Visual hallucinatory experiences may not be exclusive to psychiatric disorders, as similar experiences can occur in trauma patients and potentially affect diagnosis. Further research is needed to characterize the differences between visual hallucinations in psychosis and trauma-associated visual phenomena.
AUSTRALASIAN PSYCHIATRY
(2022)
Article
Neurosciences
Hugo A. E. Morandini, Pradeep Rao, Sean D. Hood, Kristi Griffiths, Timothy J. Silk, Florian D. Zepf
Summary: The study did not find a significant relationship between dietary omega-3 intake and resting-state functional connectivity or vigilant attention performance.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Davinder Hans, Anthony Rengel, Jaspreet Hans, Darryl Bassett, Sean Hood
Summary: Objective N-acetylcysteine has shown potential as a rapidly acting adjunctive treatment in reducing suicidality and depressive symptoms in intentional medication overdose patients.
Article
Public, Environmental & Occupational Health
D. Ashwin, L. Gibson, E. Hagemann, N. D'Vaz, N. Bear, D. Silva
Summary: Maternal diet during pregnancy can affect the body fat percentage of newborn infants, with higher adherence to the Mediterranean diet associated with lower body fat percentage.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2022)
Article
Rehabilitation
Nadine Smith, Simon Garbellini, Natasha Bear, Ashleigh Thornton, Peta Watts, Noula Gibson
Summary: This study aimed to assess the feasibility of using parent-reported outcome measures for children with dyskinetic cerebral palsy (CP), and explore the effects of individualized movement intervention. The results showed that the assessment tools used were feasible in evaluating pain, sleep, and comfort, and individualized movement intervention may help improve pain, sleep, and ease of care and comfort.
DISABILITY AND REHABILITATION
(2023)
Article
Allergy
Paul Porter, Joanna Brisbane, Udantha Abeyratne, Natasha Bear, Scott Claxton
Summary: This study aimed to develop a smartphone-based diagnostic algorithm to early and accurately recognize asthma exacerbations by analyzing cough events and patient-reported features. The results showed that the algorithm accurately detected asthma exacerbations without requiring clinical examination or lung function testing.
Article
Health Care Sciences & Services
Paul Porter, Huaqiong Zhou, Brooke Schneider, Jennifer Choveaux, Natasha Bear, Phillip Della, Kym Jones
Summary: This study compared the accuracy, clinical interpretability, and user experience of a patient-administered, wireless, fetal heartbeat monitor (HBM) designed for home use to in-hospital Cardiotocographic (CTG) devices. The results showed that the HBM is as accurate as CTG, providing equivalent clinical information for non-stress test analyses. It is also user-friendly and can be successfully used by expectant mothers without supervision.
NPJ DIGITAL MEDICINE
(2022)
Article
Psychology, Developmental
Jennifer A. Lewis, Natasha Bear, Nadine Smith, Felicity Baker, Olivia S. Lee, Meredith Wynter, Simon P. Paget
Summary: The aim of this study is to describe the individualized occupational performance issues identified by parents/carers and children prior to SDR surgery and analyse change up to 2 years post surgery in goal attainment and quality of life. Results demonstrate improved scores in goal attainment and improvement in functional quality of life domains. Collaborative goal setting is an integral part of family-centred rehabilitation practice.
CHILD CARE HEALTH AND DEVELOPMENT
(2023)
Article
Medicine, General & Internal
Sue-Anne Davidson, Roslyn Ward, Catherine Elliott, Courtenay Harris, Natasha Bear, Ashleigh Thornton, Alison Salt, Jane Valentine
Summary: This study reports on knowledge translation strategies and outcomes from the implementation of early detection guidelines for cerebral palsy in a state-wide tertiary early intervention service. The study found that the implementation strategies effectively reduced referral age and improved the delivery of early detection assessments. Furthermore, social determinants such as social disadvantage and adverse childhood experiences were found to be associated with early detection outcomes.
Article
Psychology, Multidisciplinary
Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Sean D. Hood, Hans Stampfer, Gary K. Hulse
Summary: This study aimed to investigate the efficacy and safety of low-dose continuous flumazenil infusion in the treatment of generalized anxiety disorder (GAD). The results showed that low-dose continuous flumazenil infusion can effectively manage GAD symptoms without causing any changes in hepatic, renal, or hematological function.
BEHAVIORAL SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jilen Patel, Natasha Bear, Robyn Long, Steven Naoum, Linda Slack-Smith, Estie Kruger
Summary: This study conducted a process evaluation of the Kimberley Dental Team (KDT), a volunteer organization providing care to remote Aboriginal communities in Western Australia. The evaluation found that the KDT model focused on serving school-aged children and showed an increase in service types and quantity over the past decade.
COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY
(2023)
Article
Clinical Neurology
Natasha L. L. Bear, Andrew Wilson, A. Marie Blackmore, Elizabeth Geelhoed, Shannon Simpson, Katherine Langdon
Summary: This study aimed to quantify the burden of respiratory illness in cerebral palsy (CP) by comparing the costs of respiratory hospitalizations with non-respiratory hospitalizations. The results showed that respiratory hospitalizations were associated with higher costs, longer stays, and more days in intensive care units, making them a significant driver of healthcare costs. This burden was particularly seen in a subgroup of children with CP.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Pharmacology & Pharmacy
Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Kellie S. Bennett, Sean D. Hood, Hans Stampfer, Gary K. Hulse
Summary: This open-label pilot study aimed to assess the efficacy and safety of low-dose flumazenil (FMZ) for generalized anxiety disorder (GAD). The results showed that continuous low-dose FMZ infusion can reduce anxiety and stress, and improve sleep quality without serious adverse events in GAD patients. Therefore, this study suggests that low-dose continuous FMZ infusion is a safe, well-tolerated, and feasible treatment option for GAD.
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY
(2023)
Review
Pharmacology & Pharmacy
Bradley Roberts, Zahra Cooper, Stephanie Lu, Susanne Stanley, Bernadette T. Majda, Khan R. L. Collins, Lucy Gilkes, Jennifer Rodger, P. Anthony Akkari, Sean D. Hood
Summary: Pharmacogenetics (PGx) studies how individual genetic differences can affect drug responses. PGx testing can individualize primary care and provide a safer drug prescription model. It has shown promising evidence in improving drug efficacy and reducing toxicity in psychiatry. However, there are barriers hindering its implementation.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Faiz M. Kassim, Sophie Tod, Jennifer Rodger, Sean D. Hood, Joseph W. Y. Lee, Matthew A. Albrecht, Mathew T. Martin-Iverson
Summary: This study found that low doses of synthetic cannabinoids have an impact on spatial working memory and verbal working memory. Schizotypy scores were negatively correlated with deficits in working memory.
CANNABIS AND CANNABINOID RESEARCH
(2022)
