Journal
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Volume 73, Issue -, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jnutbio.2019.108220
Keywords
Intra-uterine growth restriction; microRNA-122; Hepatic fatty acid synthesis; Fatty acid oxidation; Hypothalamic genes; Energy balance; Circadian rhythm
Funding
- National Institutes of Health [HD-41230, HD-81206]
Ask authors/readers for more resources
We examined the role of hepatocyte micro-RNA-122 and hypothalamic neuropeptides, in weanling (21d) female rats exposed to calorie restriction induced growth restriction either prenatally (IUGR), postnatally (PNGR) or both (IPGR) vs. ad lib fed controls (CON). IUGR were hyperinsulinemic, hyperleptinemic and dyslipidemic with high circulating miR-122. In contrast, PNGR and IPGR displayed insufficient glucose, insulin and leptin amidst high ketones with a dichotomy in circulating miR-122 of PNGR
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
