Sensitivity of the Candida albicans trehalose-deficient mutants tps1Δ and tps2Δ to amphotericin B and micafungin

Micafungin Enhances the Human Macrophage Response to Candida albicans through β-Glucan Exposure

(2018) José Pedro Guirao-Abad et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting Candida spp. to develop antifungal agents

(2018) Tânia P. Salci et al.   DRUG DISCOVERY TODAY

Oxidative stress and aging: Learning from yeast lessons

(2018) Elis Eleutherio et al.   Fungal Biology

Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

(2018) Giselle C. de Oliveira Santos et al.   Frontiers in Microbiology

ROS formation is a differential contributory factor to the fungicidal action of Amphotericin B and Micafungin in Candida albicans

(2017) José P. Guirao-Abad et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design

(2017) Yi Miao et al.   mBio

Trehalose pathway as an antifungal target

(2016) John R. Perfect et al.   Virulence

Trehalose as antifungal target: The picture is still incomplete

(2016) Juan-Carlos Argüelles   Virulence

Echinocandin Resistance in Candida Species: a Review of Recent Developments

(2016) Nathan P. Wiederhold   Current Infectious Disease Reports

Homozygous deletion of ATC1 and NTC1 genes in Candida parapsilosis abolishes trehalase activity and affects cell growth, sugar metabolism, stress resistance, infectivity and biofilm formation

(2015) Ruth Sánchez-Fresneda et al.   FUNGAL GENETICS AND BIOLOGY

Nosocomial Candidiasis: Antifungal Stewardship and the Importance of Rapid Diagnosis

(2015) Michael A. Pfaller et al.   MEDICAL MYCOLOGY

The Production of Reactive Oxygen Species Is a Universal Action Mechanism of Amphotericin B against Pathogenic Yeasts and Contributes to the Fungicidal Effect of This Drug

(2014) Ana Cecilia Mesa-Arango et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Production of biofilm by Candida and non-Candida spp. isolates causing fungemia: Comparison of biomass production and metabolic activity and development of cut-off points

(2014) Laura Judith Marcos-Zambrano et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Phenylpropanoids of Plant Origin as Inhibitors of Biofilm Formation by Candida albicans

(2014) Jayant Shankar Raut et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Why Can’t Vertebrates Synthesize Trehalose?

(2014) Juan-Carlos Argüelles   JOURNAL OF MOLECULAR EVOLUTION

In Candida parapsilosis the ATC1 Gene Encodes for an Acid Trehalase Involved in Trehalose Hydrolysis, Stress Resistance and Virulence

(2014) Ruth Sánchez-Fresneda et al.   PLoS One

Mechanisms ofCandidabiofilm drug resistance

(2013) Heather T Taff et al.   Future Microbiology

Fungicidal Drugs Induce a Common Oxidative-Damage Cellular Death Pathway

(2013) Peter Belenky et al.   Cell Reports

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

(2013) Benjamin Matteson Vincent et al.   PLOS BIOLOGY

Candidaspecies: new insights into biofilm formation

(2012) Mayra Cuéllar-Cruz et al.   Future Microbiology

Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration

(2011) Ryan J. Mailloux et al.   BIOCHEMICAL JOURNAL

Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst

(2011) Fernanda Sangalli-Leite et al.   MICROBES AND INFECTION

Microtiter Dish Biofilm Formation Assay

(2011) George A. O'Toole   Jove-Journal of Visualized Experiments

A 96 Well Microtiter Plate-based Method for Monitoring Formation and Antifungal Susceptibility Testing of Candida albicans Biofilms

(2010) Christopher G. Pierce et al.   Jove-Journal of Visualized Experiments

Role of trehalose-6P phosphatase (TPS2) in stress tolerance and resistance to macrophage killing in Candida albicans

(2009) María Martínez-Esparza et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The Trehalose Pathway Regulates Mitochondrial Respiratory Chain Content through Hexokinase 2 and cAMP inSaccharomyces cerevisiae

(2009) Abdelmajid Noubhani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined Inactivation of the Candida albicans GPR1 and TPS2 Genes Results in Avirulence in a Mouse Model for Systemic Infection

(2008) M. M. Maidan et al.   INFECTION AND IMMUNITY

Biofilm Formation by Lactic Acid Bacteria and Resistance to Environmental Stress

(2008) Hiromi Kubota et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING