Article
Immunology
Robert Cohen, Corinne Levy, Naim Ouldali, Marie Goldrey, Stephane Bechet, Stephane Bonacorsi, Emmanuelle Varon
Summary: Most non-PCV13 serotypes had low invasive disease potential, while among serotypes with the highest invasive disease potential, most are included in PCV20 vaccine.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
Camille Van Camp, Charlotte Fraikin, Elodie Claverie, Rob Onderwater, Ruddy Wattiez
Summary: The freshwater cyanobacterium Gloeothece verrucosa, known for its circadian rhythm and exopolysaccharide production, was studied to understand the impact of carbon to nitrogen ratio on growth, metabolism, and exopolysaccharide production. The results showed that nitrogen concentration played a significant role in promoting growth and influencing exopolysaccharide content, with higher ratios favoring higher production. The findings suggest that the exopolysaccharides of Gloeothece verrucosa could be a sustainable alternative for plant biostimulation.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Chemistry, Medicinal
Ravinder Mettu, Yu-Hsuan Lih, Hanmanth Reddy Vulupala, Chiang-Yun Chen, Mei-Hua Hsu, Hong-Jay Lo, Kuo-Shiang Liao, Yang-Yu Cheng, Cheng-Hsun Chiu, Chung-Yi Wu
Summary: In this study, a library of capsular polysaccharide fragments of Streptococcus pneumoniae was constructed through chemical synthesis. Eight selected fragments were found to induce opsonic antibodies with bactericidal activities and moderate cross-reactivities.
ACS INFECTIOUS DISEASES
(2022)
Article
Biotechnology & Applied Microbiology
Tomasz Zimny
Summary: The article discusses amendment options for the EU authorization procedures of NGT products and the consequences for the sector and research institutions. It emphasizes the need for a reform in the EU regulatory system to ensure competitiveness for EU researchers and investors.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Ergonomics
Narelle Haworth, Amy Schramm, Divera Twisk
Summary: The study found that illegal behaviors among shared e-scooter riders in inner-city Brisbane decreased from February to October 2019, while the usage of private e-scooters increased, suggesting an improvement in e-scooter safety.
ACCIDENT ANALYSIS AND PREVENTION
(2021)
Article
Neurosciences
Claudia Pisanu, Donatella Congiu, Giovanni Severino, Raffaella Ardau, Caterina Chillotti, Maria Del Zompo, Bernhard T. Baune, Alessio Squassina
Summary: Through GWAS datasets, shared genetic determinants between bipolar disorder and risk-taking propensity have been identified, with 15 novel and specific loci associated with bipolar disorder and 22 loci associated with risk-taking propensity. These findings may contribute to the development of innovative pharmacotherapy for patients with bipolar disorder with increased risk-taking propensity.
NEUROPSYCHOPHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Xue Li, Menglin Wu, Jiang Li, Qi Guo, Yang Zhao, Xuening Zhang
Summary: Atherosclerosis plaques, caused by cerebrovascular and coronary artery disease, are a major cause of death and morbidity worldwide. Accurately assessing and identifying the degree of plaque is crucial for predicting risk and monitoring treatment outcomes. Traditional imaging techniques have limitations, while nanomedicine-based imaging techniques show great potential for characterizing and detecting plaques. This review discusses recent advancements in targeted nanomedicine-based approaches for imaging and risk stratification of atherosclerosis plaques, as well as the challenges and opportunities for future development and clinical translation.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
James Magnus Rae, Barbara Jachimska
Summary: This study revealed that the interaction between BSA and G5.5 PAMAM dendrimers is driven by both electrostatic and hydrophobic forces. The binding alters the structure, charge distribution, and secondary structure of proteins.
Article
Soil Science
Heike Schimmel, Melanie Braun, Jens-Arne Subke, Wulf Amelung, Roland Bol
Summary: Research has shown that afforestation has a legacy effect on potential subsoil SOC losses with global warming, while nutrient addition has no significant impact on topsoil organic matter decomposition.
SOIL BIOLOGY & BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Christiana C. C. Christodoulou, Eleni Zamba Papanicolaou
Summary: This study identified differentially expressed genes (DEGs), pathways, and miRNAs related to Huntington's Disease (HD) using bioinformatics analysis. The findings shed light on the underlying molecular mechanisms of HD and provide potential therapeutic targets.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Immunology
Xi Huang, Yiwen Sun, Jia Song, Yusong Huang, Huizhong Shi, Aihua Qian, Yuncan Cao, Youci Zhou, Qijun Wang
Summary: In this study, a prognostic model for colon cancer was constructed based on fatty acid metabolism genes. The model showed potential in predicting the response to immunotherapy in colon cancer patients.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Environmental Sciences
Meron Teferi Taye, Ellen Dyer, Katrina J. Charles, Linda C. Hirons
Summary: Understanding the influence of large-scale oceanic and atmospheric variability on rainfall over Ethiopia is crucial for improving seasonal forecasting and informing water management decisions. This study analyzed drivers of Ethiopia's main rainy season, showing local spatial variations and strong correlations between sea surface temperatures and rainfall. It also highlighted mechanisms such as the East African Low-Level Jet and the impact of ENSO and positive IOD events on Ethiopian rainfall. Sub-national analysis on the Awash basin revealed distinct climate zones with different relationships to SSTs. These findings emphasize the importance of locally relevant climate systems for water management in Ethiopia.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Xibo Sun, Xiaoming Liang, Limin Chen, Chenghao Liao, Yongbo Zhang, Daiqi Ye
Summary: China has become the world leader in crude oil processing capacity in 2021. However, the petroleum refining industry generates significant VOC emissions, and the understanding of VOC emissions in this industry is still limited. This study systematically evaluated the historical emissions and reduction of VOCs in the petroleum refining industry in Guangdong, China's major province for crude oil processing, from 2001 to 2020. The results showed that VOC emissions followed an increasing-then-decreasing trend, with storage tanks and wastewater treatment as the largest sources. Efforts to reduce VOC emissions have shown positive results.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Biotechnology & Applied Microbiology
Jitender Singh, Shubhashis Das, Kapuganti Jagadis Gupta, Aashish Ranjan, Christine H. Foyer, Jitendra Kumar Thakur
Summary: The SWEET family of transporters in plants is a novel class of sugar carriers that can transport sugars, sugar alcohols, and hormones. They play important roles in intercellular sugar transport and influence various physiological processes. SWEETs regulate the development of sink organs, respond to abiotic stresses, and affect host-pathogen interactions.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Environmental Sciences
Elisabeth S. Rodland, Ole Christian Lind, Malcolm J. Reid, Lene S. Heier, Elvis D. Okoffo, Cassandra Rauert, Kevin V. Thomas, Sondre Meland
Summary: Studies have shown that tire and road wear particles are major sources of microplastic contamination. There is a wide variation in the mass concentrations and snow mass loads of these particles in snow. Contrary to previous findings, the speed limit is found to be a key variable impacting the mass concentrations. The presence of large amounts of suspended solids in roadside snow highlights the need for treatment before release into the environment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)