T Cell– and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer

Immune Checkpoint Inhibition in Sepsis

(2019) Richard S. Hotchkiss et al.   CRITICAL CARE MEDICINE

Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis

(2019) Ting Wen et al.   JOURNAL OF CLINICAL INVESTIGATION

Management of Sepsis-Induced Immunosuppression

(2018) Fabienne Venet et al.   CRITICAL CARE CLINICS

Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration

(2018) Lukose K. Thampy et al.   PLoS One

Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery

(2018) Philip A. Efron et al.   SURGERY

Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer

(2018) Julie G Grossman et al.   OncoImmunology

Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn Disease Reveals Tissue-Specific Characteristics and Drug Targets

(2018) Werna T. Uniken Venema et al.   GASTROENTEROLOGY

Persistent Inflammation and Anemia among Critically Ill Septic Patients

(2018) Tyler J. Loftus et al.   Journal of Trauma and Acute Care Surgery

Understanding Immunosuppression after Sepsis

(2017) Fatemeh Fattahi et al.   IMMUNITY

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation

(2016) Ana C. Anderson et al.   IMMUNITY

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1

(2016) Andriani C. Patera et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

(2016) Emma E Davenport et al.   Lancet Respiratory Medicine

Sepsis and septic shock

(2016) Richard S. Hotchkiss et al.   Nature Reviews Disease Primers

A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis — A Prospective Multicenter Phase II Diagnostic Study

(2016) Michael Bauer et al.   EBioMedicine

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

A new rhesus macaque assembly and annotation for next-generation sequencing analyses

(2014) Aleksey V Zimin et al.   Biology Direct

Parallels between Cancer and Infectious Disease

(2014) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Arginine depletion increases susceptibility to serious infections in preterm newborns

(2014) Shiraz Badurdeen et al.   PEDIATRIC RESEARCH

Reactivation of Multiple Viruses in Patients with Sepsis

(2014) Andrew H. Walton et al.   PLoS One

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunotherapy for Sepsis — A New Approach against an Ancient Foe

(2010) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE