Long non-coding RNA HOTTIP enhances IL-6 expression to potentiate immune escape of ovarian cancer cells by upregulating the expression of PD-L1 in neutrophils
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Long non-coding RNA HOTTIP enhances IL-6 expression to potentiate immune escape of ovarian cancer cells by upregulating the expression of PD-L1 in neutrophils
Authors
Keywords
Ovarian cancer, Neutrophils, Interleukin-6, Programmed death-ligand 1, HOXA transcript at the distal tip, Immune escape
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 38, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-18
DOI
10.1186/s13046-019-1394-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immunotherapy in ovarian cancer: fake news or the real deal?
- (2019) Christian Marth et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Safety and clinical activity with an anti-PD-1 antibody JS001 in advanced melanoma or urologic cancer patients
- (2019) Bixia Tang et al. Journal of Hematology & Oncology
- Long Noncoding RNA HOTTIP Promotes Nasopharyngeal Cancer Cell Proliferation, Migration, and Invasion by Inhibiting miR-4301
- (2019) Meiqin Shen et al. MEDICAL SCIENCE MONITOR
- LncRNA MALAT1 promotes tumorigenesis and immune escape of diffuse large B cell lymphoma by sponging miR-195
- (2019) Qing-Ming Wang et al. LIFE SCIENCES
- The long non-coding RNA HOTTIP promotes breast cancer cell migration, invasion, and epithelial-mesenchymal transition via Wnt/β-catenin pathway
- (2019) Sijia Han et al. Biochemistry and Cell Biology
- Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment
- (2019) Chin-King Looi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- LncRNA HOTTIP-Mediated HOXA11 Expression Promotes Cell Growth, Migration and Inhibits Cell Apoptosis in Breast Cancer
- (2018) Yanqin Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
- (2018) Yusheng Cheng et al. Cell Death & Disease
- Long noncoding RNA HOTTIP is a significant indicator of ovarian cancer prognosis and enhances cell proliferation and invasion
- (2018) Ting Zou et al. Cancer Biomarkers
- Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells
- (2018) Mingkui Mu et al. OncoTargets and Therapy
- Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8+ T cells in the tumor microenvironment
- (2018) Yasuko Tada et al. Journal for ImmunoTherapy of Cancer
- Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway
- (2017) Ting-ting Wang et al. GUT
- The need for a network to establish and validate predictive biomarkers in cancer immunotherapy
- (2017) Giuseppe V. Masucci et al. Journal of Translational Medicine
- Long Non-coding RNA HOXA11 Antisense Promotes Cell Proliferation and Invasion and Predicts Patient Prognosis in Serous Ovarian Cancer
- (2017) Ga Won Yim et al. Cancer Research and Treatment
- CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1
- (2016) Y. Lee et al. CLINICAL CANCER RESEARCH
- Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib
- (2016) Shao-Lai Zhou et al. GASTROENTEROLOGY
- IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer
- (2016) Thomas A Mace et al. GUT
- The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer
- (2016) Nan Zhang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis
- (2016) Xue Wang et al. JOURNAL OF HEPATOLOGY
- HOTTIP and HOXA13 are oncogenes associated with gastric cancer progression
- (2016) SHUAI CHANG et al. ONCOLOGY REPORTS
- IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer
- (2015) K Abiko et al. BRITISH JOURNAL OF CANCER
- Functions and Mechanisms of Long Noncoding RNAs in Ovarian Cancer
- (2015) Chengcheng Ren et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma
- (2015) Gaixia He et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- IL-6 Regulates Neutrophil Trafficking during Acute Inflammation via STAT3
- (2014) C. A. Fielding et al. JOURNAL OF IMMUNOLOGY
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- Long non-coding RNAs and cancer: a new frontier of translational research?
- (2012) R Spizzo et al. ONCOGENE
- The comprehensive assessment of local immune status of ovarian cancer by the clustering of multiple immune factors
- (2011) Junzo Hamanishi et al. CLINICAL IMMUNOLOGY
- The Origin and Pathogenesis of Epithelial Ovarian Cancer: A Proposed Unifying Theory
- (2010) Robert J. Kurman et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway
- (2009) Lin Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ovarian Cancer Cells Modulate Human Blood Neutrophils Response to ActivationIn Vitro
- (2008) M. Klink et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now