Journal
JOURNAL OF DERMATOLOGICAL TREATMENT
Volume 32, Issue 2, Pages 261-263Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09546634.2019.1654067
Keywords
Guselkumab; hidradenitis suppurativa; IL-23
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The case report describes a 28-year-old woman with HS, psoriasis, and CD, who was successfully treated with guselkumab after failing multiple other biologic agents. Guselkumab represents a promising therapeutic option for recalcitrant HS patients with inflammatory comorbidities in which IL-23 plays a role.
Background: Hidradenitis suppurativa (HS) is a debilitating skin condition whose pathogenesis is poorly understood, although interleukin (IL)-23 may play a role. IL-23 is also implicated in the pathogenesis of Crohn's disease (CD) and psoriasis, both of which can occur in patients with HS. Case report: We present the case of a 28-year-old woman with HS, psoriasis, and CD, who was successfully treated with guselkumab after failing multiple other biologic agents. Conclusion: Guselkumab represents a promising therapeutic option for recalcitrant HS patients with inflammatory comorbidities in which IL-23 plays a role.
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