Journal
JOURNAL OF CUTANEOUS MEDICINE AND SURGERY
Volume 23, Issue 6, Pages 608-612Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/1203475419874444
Keywords
case series; cyclosporine; cyclosporine A; Fuchs syndrome; MIRM; Mycoplasma pneumoniae-induced rash and mucositis; mucositis; mycoplasma; Mycoplasma pneumoniae-associated mucositis; MPAM; pediatric; Stevens-Johnson syndrome; SJS; therapeutics
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Background: Mycoplasma pneumoniae-induced rash and mucositis (MIRM) is a relatively newly recognized clinical entity that typically presents with predominant mucositis accompanied by variable cutaneous involvement 7-9 days after the onset of prodromal symptoms. There are no evidence-based guidelines for treatment, and current standards of care may include supportive therapy, antibiotics, corticosteroids, and intravenous immunoglobulin . Objective: This case series aims to describe the potential efficacy of cyclosporine A (CsA) in the treatment of MIRM. Methods: The present case series details our use of CsA early in the course of MIRM in 3 pediatric patients. Results: Rapid clinical resolution was observed following CsA therapy. Conclusions: We suggest that early initiation of CsA may be an effective therapeutic option for MIRM.
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