Bioreductive deprotection of 4-nitrobenzyl group on thymine base in oligonucleotides for the activation of duplex formation

Published 2015 View Full Article

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Title
Bioreductive deprotection of 4-nitrobenzyl group on thymine base in oligonucleotides for the activation of duplex formation
Authors
Keywords
Nucleic acid-based therapeutics, Prodrug, Protecting group, Hypoxia, Hybridization
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 25, Issue 23, Pages 5632-5635
Publisher
Elsevier BV
Online
2015-10-25
DOI
10.1016/j.bmcl.2015.10.025

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