Article
Immunology
Ebru Yuce
Summary: The role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in predicting spontaneous preterm birth was investigated. Retrospective data collected from hospital records between February 2018 and November 2022 showed that NLR and PLR values can predict preterm birth with high sensitivity and specificity. Predicting preterm birth allows for sensitive and smooth management of the pregnancy process.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Article
Psychiatry
Hector Cabello-Rangel, Marisol Basurto-Morales, Elizabeth Botello-Aceves, Osiris Pazaran-Galicia
Summary: This study described the differences in mean platelet volume (MPV), platelet count, and neutrophil/lymphocyte ratio (NLR) between patients with schizophrenia and healthy controls, and examined their correlation with the duration of untreated psychosis (DUP). The results showed that patients with schizophrenia had higher MPV levels than healthy controls, but the difference was not statistically significant. Additionally, DUP did not have a significant correlation with the blood parameters analyzed.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Haihua Wu, Hui Zhou, Panfeng Chen
Summary: This study evaluated the correlation between neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV) with parameters related to gout activity. The results showed that NLR and PLR were elevated and MPV was decreased in gout patients. NLR and PLR were positively correlated with inflammatory markers, while MPV was negatively correlated. The findings suggest that NLR, PLR, and MPV can be used as complementary tools to evaluate gout activity.
Article
Cardiac & Cardiovascular Systems
Martha Fors, Santiago Ballaz, Hegira Ramirez, Francisco X. Mora, Mary Pulgar-Sanchez, Kevin Chamorro, Esteban Fernandez-Moreira
Summary: Sex-dependent differences exist in the contribution of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and mean platelet volume-to-platelet ratio (MPR) to COVID-19 severity and mortality. The mortality rate of COVID-19 is higher among men, and men have higher levels of NLR, MLR, and MPR compared to women. NLR, MLR, and PLR have better sensitivity for predicting pneumonia severity in men, while their specificity is enhanced in women.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Yasemin Kilic Ozturk, Hande Ileri, Burcu Sen Sahin, Merve Dagci
Summary: Chronic inflammation is closely linked to the development of life-threatening chronic diseases, including cancer. This study aimed to assess the potential of neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) as indicators of metastasis in lung cancer. A retrospective cross-sectional study was conducted on lung cancer patients admitted to a referral hospital's Palliative Care Unit between January 2019 and February 2020. Patient characteristics, distant organ metastasis, treatments, NLR, and MPV values were analyzed. The study found that lung cancer patients with metastasis had higher MPV values, suggesting that MPV could serve as an accessible and effective predictor of metastasis regardless of the pathological type.
Article
Medicine, General & Internal
Da Eun Ko, Hei Jin Yoon, Sang Beom Nam, Suk Won Song, Gisong Lee, Sung Yeon Ham
Summary: The study found that preoperative NLR, PLR, and MPV can predict 1-year mortality in patients undergoing open AAA repair, with NLR and PLR showing better predictive power in ruptured cases.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
E. Weijian, Zhixin Wang, Mingquan Pang, Yongliang Lu, Haining Fan
Summary: The NLR and PLR of AE patients were higher than those of CE patients, and the high inflammation of CE patients may be correlated to the reproductive mode of Echinococcus multilocularis. PLR and NLR have certain diagnostic values for disease classification, but PLR has higher specificity when compared with NLR.
JOURNAL OF INFLAMMATION RESEARCH
(2021)
Article
Health Care Sciences & Services
Georgios Tzikos, Ioannis Alexiou, Sokratis Tsagkaropoulos, Alexandra-Eleftheria Menni, Georgios Chatziantoniou, Soultana Doutsini, Theodosios Papavramidis, Vasilios Grosomanidis, George Stavrou, Katerina Kotzampassi
Summary: In this study, the researchers investigated whether NLR and PLR could predict mortality and length of hospital stay after cardiac surgery. The results showed that NLR and PLR are efficient predictive factors for 90-day mortality and length of stay in cardiac surgery patients. Monitoring NLR and PLR postoperatively could provide a reliable predictor of patients' outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Pediatrics
Yuksel Kurban, Yasemin Alan, Ibrahim Uyar, Zeliha Atak, Onder Aydemir, Abdulmecit Oktem
Summary: This study investigated the levels of NLO and MPV in preterm birth patients, finding that NLO was higher and MPV was lower in the preterm birth group, potentially serving as markers of inflammation. The rate of caesarean section was higher in the preterm group compared to the control group.
PAEDIATRIC RESPIRATORY REVIEWS
(2021)
Article
Hematology
Amaya Llorente-Chavez, Eduardo Martin-Nares, Carlos Nunez-Alvarez, Gabriela Hernandez-Molina
Summary: In this study, we assessed the performance of MPV, PLR, NLR, and MPV-to-lymphocyte ratio in APS patients and found that baseline MPV and PLR may help identify APS patients according to their thrombotic or thrombocytopenic phenotype. These variables change during acute events and may reflect physiopathological or compensatory mechanisms in APS.
THROMBOSIS RESEARCH
(2021)
Article
Medicine, General & Internal
Milena-Adina Man, Lavinia Davidescu, Nicoleta-Stefania Motoc, Ruxandra-Mioara Rajnoveanu, Cosmina-Ioana Bondor, Carmen-Monica Pop, Claudia Toma
Summary: The study showed that NLR and PLR had limited ability to differentiate between various respiratory diseases and were not suitable for making the differential diagnosis.
Article
Psychiatry
Qi Zheng, Jin Liu, YaJuan Ji, Yan Zhang, XinChao Chen, BangShan Liu
Summary: This study compared the levels of inflammatory indicators derived from blood routine tests between adolescents with and without non-suicidal self-injury (NSSI). The results showed that adolescents with NSSI had significantly higher MLR and PLR compared to those without NSSI. MLR and PLR were independently associated with NSSI. ROC curve analysis demonstrated that MLR and PLR can be used to differentiate NSSI from non-NSSI.
Article
Pediatrics
Spyridoula Gysi, Michael Doulberis, Corinne Legeret, Henrik Kohler
Summary: This retrospective analysis explored the utilization of PYMS as a screening tool for malnutrition in pediatric inpatients and investigated the correlation between PYMS and NLR and PLR. The study found a potential value of PLR as a predictive marker for moderate to severe malnutrition in hospitalized children.
Article
Biotechnology & Applied Microbiology
Mariam M. Abd El-Azim, Mona K. Mousa, Ragaa M. Abdelmaaboud, Nabil N. Rezq, Sarah S. Mohammed
Summary: Snakebite incidence is highest in males from rural areas, affecting lower limbs, occurring at night, and in autumn. NLR and PLR can predict hemotoxic snakebite, with combined values offering a more accurate prediction and correlating with longer hospital stays. MPV does not play a role in prognosis. Serial NLR and PLR levels can assess early treatment response.
Article
Immunology
Pauline Jacob, Julie Bonnefoy, Stephanie Ghislin, Jean-Pol Frippiat
Summary: This study evaluated the relevance of two easily-implemented biomarkers for monitoring immune system in astronauts and suggested using neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) to assess long-lasting immune diseases.
FRONTIERS IN IMMUNOLOGY
(2022)