A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

CD4 + T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness

(2017) Tomasz Ahrends et al.   IMMUNITY

Modulating IgG effector function by Fc glycan engineering

(2017) Tiezheng Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

(2017) Rajasekharan Somasundaram et al.   Nature Communications

Fcγ Receptor Heterogeneity in Leukocyte Functional Responses

(2017) Carlos Rosales   Frontiers in Immunology

The Emerging Role of B Cells in Tumor Immunity

(2016) Peiling Tsou et al.   CANCER RESEARCH

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

Human CD4+ T-Cells: A Role for Low-Affinity Fc Receptors

(2016) Anil K. Chauhan   Frontiers in Immunology

Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2

(2015) Eric F. Zhu et al.   CANCER CELL

Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

(2015) David J. DiLillo et al.   CELL

Induced Expression of FcγRIIIa (CD16a) on CD4+T Cells Triggers Generation of IFN-γhighSubset

(2015) Anil K Chauhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity

(2015) Yaron Carmi et al.   NATURE

Direct tumor recognition by a human CD4+ T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses

(2015) Junko Matsuzaki et al.   Scientific Reports

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L

(2013) M. Bodogai et al.   CANCER RESEARCH

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Generation of T cell receptor–retrogenic mice: improved retroviral-mediated stem cell gene transfer

(2013) Matthew L Bettini et al.   Nature Protocols

B Cells Promote Tumor Progression via STAT3 Regulated-Angiogenesis

(2013) Chunmei Yang et al.   PLoS One

Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?

(2013) L. M. Coussens et al.   SCIENCE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Adoptive Transfer of Tumor Reactive B Cells Confers Host T-Cell Immunity and Tumor Regression

(2011) Q. Li et al.   CLINICAL CANCER RESEARCH

Naive tumor-specific CD4+T cells differentiated in vivo eradicate established melanoma

(2010) Ying Xie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

(2010) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice

(2010) D. J. DiLillo et al.   JOURNAL OF IMMUNOLOGY

Affinity and Avidity in Antibody-Based Tumor Targeting

(2009) Stephen I. Rudnick et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

A systematic review of humoral immune responses against tumor antigens

(2009) Miriam Reuschenbach et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness

(2008) Gerald Willimsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

(2008) Naomi N. Hunder et al.   NEW ENGLAND JOURNAL OF MEDICINE