LEAP2 changes with body mass and food intake in humans and mice

Identifying the binding mechanism of LEAP2 to receptor GHSR1a

(2019) Jia-Hui Wang et al.   FEBS Journal

LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor

(2018) Xuecai Ge et al.   Cell Metabolism

N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor

(2018) Céline M’Kadmi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ghrelin receptors mediate ghrelin-induced excitation of agouti-related protein/neuropeptide Y but not pro-opiomelanocortin neurons

(2017) Shao-Rui Chen et al.   JOURNAL OF NEUROCHEMISTRY

Butyrylcholinesterase gene transfer in obese mice prevents postdieting body weight rebound by suppressing ghrelin signaling

(2017) Vicky Ping Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ghrelin as a Survival Hormone

(2017) Bharath K. Mani et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals

(2016) Bharath K. Mani et al.   JOURNAL OF CLINICAL INVESTIGATION

Brain imaging demonstrates a reduced neural impact of eating in obesity

(2016) Nancy Puzziferri et al.   Obesity

Obesity Impairs the Action of the Neuroendocrine Ghrelin System

(2016) Jeffrey M. Zigman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ghrelin Inhibition Restores Glucose Homeostasis in Hepatocyte Nuclear Factor-1α (MODY3)–Deficient Mice

(2015) François Brial et al.   DIABETES

Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

(2015) Farhana Naznin et al.   JOURNAL OF ENDOCRINOLOGY

Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone

(2015) Yuanyuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ghrelin

(2015) T.D. Müller et al.   Molecular Metabolism

Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet

(2014) Matthew R. McFarlane et al.   Cell Metabolism

Evidence That Diet-Induced Hyperleptinemia, but Not Hypothalamic Gliosis, Causes Ghrelin Resistance in NPY/AgRP Neurons of Male Mice

(2014) Dana I. Briggs et al.   ENDOCRINOLOGY

Calorie-Restricted Weight Loss Reverses High-Fat Diet-Induced Ghrelin Resistance, Which Contributes to Rebound Weight Gain in a Ghrelin-Dependent Manner

(2013) Dana I. Briggs et al.   ENDOCRINOLOGY

Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin

(2013) Qian Wang et al.   Molecular Metabolism

Profound Hypoglycemia in Starved, Ghrelin-deficient Mice Is Caused by Decreased Gluconeogenesis and Reversed by Lactate or Fatty Acids

(2012) Robert Lin Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Missing Risk: MRI and MRS Phenotyping of Abdominal Adiposity and Ectopic Fat

(2011) E. Louise Thomas et al.   Obesity

Central mechanisms involved in the orexigenic actions of ghrelin

(2011) Zane B. Andrews   PEPTIDES

Structural and Functional Analysis of Human Liver-Expressed Antimicrobial Peptide 2

(2010) Sónia Troeira Henriques  et al.   CHEMBIOCHEM

Diet-Induced Obesity Causes Ghrelin Resistance in Arcuate NPY/AgRP Neurons

(2010) Dana I. Briggs et al.   ENDOCRINOLOGY

The Hyperphagic Effect of Ghrelin Is Inhibited in Mice by a Diet High in Fat

(2010) James V. Gardiner et al.   GASTROENTEROLOGY

Metabolic Status Regulates Ghrelin Function on Energy Homeostasis

(2010) Dana I. Briggs et al.   NEUROENDOCRINOLOGY

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

(2010) T.-J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and functional analyses of liver expressed antimicrobial peptide-2 (LEAP-2) variant forms in human tissues

(2009) Alison Howard et al.   CELLULAR IMMUNOLOGY

GOAT links dietary lipids with the endocrine control of energy balance

(2009) Henriette Kirchner et al.   NATURE MEDICINE

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Role of Ghrelin in the Relationship Between Hyperphagia and Accelerated Gastric Emptying in Diabetic Mice

(2008) Pieter–Jan Verhulst et al.   GASTROENTEROLOGY

Acyl and Total Ghrelin Are Suppressed Strongly by Ingested Proteins, Weakly by Lipids, and Biphasically by Carbohydrates

(2008) Karen E. Foster-Schubert et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Novel Ghrelin Assays Provide Evidence for Independent Regulation of Ghrelin Acylation and Secretion in Healthy Young Men

(2008) Jianhua Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ghrelin octanoylation mediated by an orphan lipid transferase

(2008) J. A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure

(2007) Paul T. Pfluger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Characterization of Adult Ghrelin and Ghrelin Receptor Knockout Mice under Positive and Negative Energy Balance

(2007) Yuxiang Sun et al.   ENDOCRINOLOGY