Hair follicle regeneration suppresses Ras-driven oncogenic growth

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Correction of aberrant growth preserves tissue homeostasis

(2017) Samara Brown et al.   NATURE

Cancer-Associated Mutations in Endometriosis without Cancer

(2017) Michael S. Anglesio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma

(2016) William E. Lowry et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A single dividing cell population with imbalanced fate drives oesophageal tumour growth

(2016) Julia Frede et al.   NATURE CELL BIOLOGY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool

(2015) Kailin R. Mesa et al.   NATURE

Intravital imaging of hair follicle regeneration in the mouse

(2015) Cristiana M Pineda et al.   Nature Protocols

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Cell competition: Winning out by losing notch

(2015) Maria P Alcolea et al.   CELL CYCLE

Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacanthomas and squamous cell carcinomas of the skin

(2014) Franziska Berger et al.   PATHOLOGY RESEARCH AND PRACTICE

 -Catenin Activation Regulates Tissue Growth Non-Cell Autonomously in the Hair Stem Cell Niche

(2014) E. R. Deschene et al.   SCIENCE

RNAi screens in mice identify physiological regulators of oncogenic growth

(2013) Slobodan Beronja et al.   NATURE

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

(2012) Vladimir Ratushny et al.   JOURNAL OF CLINICAL INVESTIGATION

Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

(2012) Panteleimon Rompolas et al.   NATURE

Detectable clonal mosaicism from birth to old age and its relationship to cancer

(2012) Cathy C Laurie et al.   NATURE GENETICS

Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling

(2012) Rachel Sennett et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of a TGFβ type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFβ signaling in tumor promotion and progression

(2010) Lauren Mordasky Markell et al.   CARCINOGENESIS

Sun-Induced Nonsynonymous p53 Mutations Are Extensively Accumulated and Tolerated in Normal Appearing Human Skin

(2010) Patrik L. Ståhl et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

(2010) Slobodan Beronja et al.   NATURE MEDICINE

RasGRP1 Transgenic Mice Develop Cutaneous Squamous Cell Carcinomas in Response to Skin Wounding

(2009) Federico R. Diez et al.   AMERICAN JOURNAL OF PATHOLOGY

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

(2009) Valentina Greco et al.   Cell Stem Cell

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia

(2009) A. M. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene

(2009) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CK19CreERTknockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs

(2008) Anna L. Means et al.   GENESIS

Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter

(2007) Masayuki Endo et al.   MOLECULAR THERAPY