Article
Chemistry, Multidisciplinary
Eugenio Jannelli, Alessandro Ivone, Stefano Rossi, Matteo Ghiara, Alberto Castelli, Gianluigi Pasta, Salvatore Annunziata, Camilla Torriani, Mario Mosconi, Francesco Benazzo
Summary: This study aims to report the clinical and functional outcomes of patients who underwent total knee arthroplasty revision in the mid-long term follow-up. It also investigates the potential differences in postoperative outcomes based on the preoperative cause of revision. The results showed that constrained condylar knee prostheses can be considered a viable option for complex cases of total knee arthroplasty revision, with satisfactory long-term results. Additionally, a preoperative diagnosis of infection is associated with worse clinical and functional outcomes.
APPLIED SCIENCES-BASEL
(2022)
Article
Orthopedics
C. Theil, J. Schwarze, G. Gosheger, L. Poggenpohl, T. Ackmann, B. Moellenbeck, T. Schmidt-Braekling, H. Ahrens
Summary: The study found that single-design CCK implants have excellent long-term survival in primary TKA, but worse survival in revision TKA. Males, smokers, and obese patients are at higher risk for revision. Infection remains a major concern for re-revision cases.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Review
Orthopedics
Lenka Stroobant, Thijmen de Taeye, Paul Byttebier, Stefaan Van Onsem, Ewoud Jacobs, Arne Burssens, Jan Victor
Summary: This systematic review and meta-analysis compared the survivorship and clinical outcome between CCK and RHK in revision TKA. The results showed no significant difference in survivorship or clinical outcome between CCK and RHK patients.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Biotechnology & Applied Microbiology
Bernardo Innocenti, Edoardo Bori, Silvia Pianigiani
Summary: Adequate fixation is crucial in revision total knee arthroplasty. Various stem solutions are available, but there is currently no evidence-based biomechanical guideline. Finite-element models were used to analyze different stem parameters, including design characteristics, fixation techniques, and the influence of slots/flutes on bone stress and risk of fracture.
BIOENGINEERING-BASEL
(2022)
Article
Orthopedics
Warran Wignadasan, Justin S. Chang, Babar Kayani, Christina Kontoghiorghe, Fares S. Haddad
Summary: This study on 41 patients undergoing revision TKA with rotating hinge components and minimum 10-years follow-up found that this approach led to satisfactory clinical outcomes and very good implant survivorship at long-term follow-up. Surgeons should consider using these versatile implants in complex revision knee arthroplasty.
Article
Orthopedics
Simarjeet Puri, Sonia Chandi, Yu-Fen Chiu, Jason L. Blevins, Geoffrey H. Westrich, Mark P. Figgie, Peter K. Sculco, Brian P. Chalmers, Elizabeth B. Gausden
Summary: This study analyzed the early outcomes of aseptic revision TKAs using a specific implant system that was recently recalled. The results showed that when components from the same manufacturer were utilized, the survivorship free from rerevision was lower than expected. However, when both the components were revised with an alternative implant system, the survivorship was comparable to contemporary reports. Cone and sleeve metaphyseal fixation as well as highly constrained implants were frequently used during rerevision TKAs.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Ittai Shichman, Christian T. Oakley, Jeremiah Thomas, Joshua C. Rozell, Vinay K. Aggarwal, Ran Schwarzkopf
Summary: Revision total knee arthroplasty (rTKA) can be performed with isolated tibial, isolated femoral, and combined tibial and femoral component exchange. Replacement of only 1 fixed component in rTKA leads to shorter operative times and decreased complexity. This study compared functional outcomes and rates of rerevision in patients undergoing partial and full rTKA.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
David Yeroushalmi, Stephen Zak, Mohamad Sharan, Jenna A. Bernstein, Ran Schwarzkopf, Joshua C. Rozell
Summary: The study found no clinically significant differences in patellar tracking when retaining the original patellar component and using a different revision implant system during revision TKA. Surgeons may consider retaining the primary patella if it is well fixed, as appropriate patellar tracking can still be expected regardless of the revision implant system used.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Chemistry, Multidisciplinary
Edoardo Bori, Bernardo Innocenti
Summary: This study used finite element analysis to investigate the effects of different interventions on bone stress, tibio-femoral contact pressure, and force when treating varus and valgus deformities with hinged total knee arthroplasty. The results showed that changes in the varus or valgus deformity degrees altered the distribution of medio-lateral stress and force, as well as the contact area. The interventions and cement had no effect on the tibio-femoral contact biomechanics, but mainly affected the distal femoral region and had negligible effect in the proximal regions.
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Matti Nikunen, Hanna Rajantie, Emilia Marttila, Johanna Snall
Summary: This study found that factors such as fracture type, orbital rim fixation, and implant malposition are associated with the need for revision surgery in primary orbital fracture reconstructions. Combined midfacial fractures with rim involvement have a higher risk for revision surgery. Patient-specific milled titanium implants are the preferred choice for achieving the best implant position.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2021)
Article
Medicine, General & Internal
Matthias Schlechter, Christoph Theil, Georg Gosheger, Burkhard Moellenbeck, Jan Schwarze, Jan Puetzler, Sebastian Bockholt
Summary: This study investigates a novel design for rotating-hinge knee (RHK) implants for knee arthroplasty. The results show that using this single-design RHK implant for revision and complex primary TKA can result in good implant survival at mid-term follow-up, with infection remaining a major concern.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Guanghui Zhao, Shuxin Yao, Xiangxiang Sun, Jianbing Ma, Jianpeng Wang
Summary: This study compared the cement penetration and clinical performance of poly-ether-ether-ketone (PEEK) prosthesis and traditional cobalt chromium molybdenum (CoCrMo) prosthesis during total knee arthroplasty (TKA). The results showed no significant difference in cement penetration between the PEEK and CoCrMo groups, as well as no remarkable differences in clinical scores, functional scores, pain scores, complications, and survivorship. Therefore, it can be concluded that PEEK implants have similar cement penetration, short-term clinical outcomes, and survivorship as traditional CoCrMo implants in TKA without added complications.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Orthopedics
Francisco A. Miralles-Munoz, Manuel Pineda-Salazar, Marta Rubio-Morales, Santiago Gonzalez-Parreno, Matias Ruiz-Lozano, Alejandro Lizaur-Utrilla
Summary: This study compared the outcome and survival between rotating hinge knee prosthesis and constrained condylar knee prosthesis for extension instability following primary total knee arthroplasty. The results showed comparable good functional outcomes and survival at long-term for both designs.
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
(2022)
Article
Orthopedics
Francesco Castagnini, Barbara Bordini, Monica Cosentino, Cristina Ancarani, Stefano Lucchini, Giovanni Bracci, Francesco Traina
Summary: Comparative study of condylar constrained knee arthroplasties (CCKAs) and rotating hinge knee arthroplasties (RHKAs) in complex primary total knee arthroplasties (TKAs) showed that both procedures have good outcomes. However, males and unstemmed CCKAs have higher failure rates.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2022)
Article
Orthopedics
D. Wautier, E. Thienpont
Summary: This study aimed to evaluate the occurrence of radiolucent lines (RLL) under the tibial base plate after total knee arthroplasty (TKA) and determine their correlation with aseptic loosening (AL). The results showed that RLLs are frequently present at the bone/implant interface after TKA, but do not necessarily indicate implant loosening.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Medicine, General & Internal
Mara Candelari, Ida Anna Cappello, Luigi Pannone, Cinzia Monaco, Edoardo Bori, Giacomo Talevi, Robbert Ramak, Mark La Meir, Ali Gharaviri, Gian Battista Chierchia, Carlo de Asmundis, Bernardo Innocenti
Summary: This study evaluates the performance of two biomaterials (MED625FLX and TPU95A) in cryoablation treatment and finds that TPU95A (1.0 and 2.5 mm) is suitable for cryoablation treatment, while MED625FLX (1.0 mm) loses its shape in the test and MED625FLX (2.5 mm) is also suitable for use with cryoenergy source. The positive results from the thermal tests on these materials and their thickness prompt further clinical investigation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biophysics
Edoardo Bori, Mehdi Mouton, Roberto Cannataro, Carlo De Asmundis, Bernardo Innocenti
Summary: The quantified self refers to individuals tracking their health and physiological parameters using technology without the supervision of clinicians. This study presents the development and optimization of a device designed to analyze sleep, activity level, and energy expenditure. The results show that the device can accurately assess energy expenditure, with a difference of less than 19% compared to the gold standard.
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY
(2023)
Article
Biophysics
Edoardo Bori, Bernardo Innocenti
Summary: A new protocol for ex vivo knee kinematics experimental activities was developed, validated, and tested in this study, which proved to provide reliable and coherent data.
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY
(2023)
Article
Biophysics
Agostino Igor Mirulla, Edoardo Bori, Laura Bragonzoni, Bernardo Innocenti
Summary: In orthopedic medical devices, it is important to address the differences in elasto-plastic behavior between bone and metallic materials to prevent mechanical issues at the bone-implant interface. This study examined the elastic behavior of different in-body gap prismatic geometries and their effectiveness in reducing prosthetic stiffness. Experimental tests and finite element models were used to evaluate the impact of these geometries on stiffness reduction. Additionally, the study explored the use of composite materials to achieve variable elastic behavior that could match the mechanical properties of bone.
JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Edoardo Bori, Bernardo Innocenti
Summary: This study used finite element analysis to investigate the effects of different interventions on bone stress, tibio-femoral contact pressure, and force when treating varus and valgus deformities with hinged total knee arthroplasty. The results showed that changes in the varus or valgus deformity degrees altered the distribution of medio-lateral stress and force, as well as the contact area. The interventions and cement had no effect on the tibio-femoral contact biomechanics, but mainly affected the distal femoral region and had negligible effect in the proximal regions.
APPLIED SCIENCES-BASEL
(2023)
Correction
Orthopedics
Fabrizio Matassi, Edoardo Bori, Niccolo Giabbani, Roberto Civinini, Bernardo Innocenti
JOURNAL OF EXPERIMENTAL ORTHOPAEDICS
(2023)
Article
Chemistry, Physical
Allegra Galas, Lorenzo Banci, Bernardo Innocenti
Summary: This study compared the effects of two same-design cruciate-retaining femoral components made with CoCr and titanium alloy on periprosthetic bone stresses using a finite element model of the implanted knee. The results showed that the titanium component induced higher bone stresses, especially at higher knee flexion angles, indicating that the CoCr component led to more stress shielding. This study has significant clinical relevance in reducing bone resorption after total knee arthroplasty.
Review
Materials Science, Biomaterials
Edoardo Bori, Clara Deslypere, Laura Estaire Munoz, Bernardo Innocenti
Summary: Despite reaching a plateau in the US and EU, the orthopedics markets in Brazil, Russia, India, and China are steadily growing. Major orthopedic companies are shifting focus towards these markets and developing tailored products, but the challenge lies in producing more affordable prostheses compared to those in the US and Europe.
Article
Orthopedics
Gianluca Castellarin, Edoardo Bori, Laurence Rapallo, Silvia Pianigiani, Bernardo Innocenti
Summary: This study compared the effects of different levels of constraint in knee biomechanics by using finite element analysis. The results showed that while the variations of the prosthetic implant did not significantly affect the stress distribution in different regions of the tibial bone, they did significantly alter the stress distribution at the interface between the prosthetic components.
Article
Orthopedics
Nazanin Daneshvarhashjin, Philippe Debeer, Bernardo Innocenti, Filip Verhaegen, Lennart Scheys
Summary: B-type glenoids are associated with increased risk of glenoid component loosening after total shoulder arthroplasty. This study quantified variabilities in scapular morphology and bone mineral density in patients with B glenoids and identified patterns of covariation between these two features. The findings suggest an asymmetrical distribution of bone density and provide insights into surgical guidelines for balancing bony shape correction and bone support quality in B glenoids.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Orthopedics
Nicola Armillotta, Edoardo Bori, Bernardo Innocenti
Summary: Unicompartmental knee arthroplasty is a less invasive treatment with advantages for patients but can be more challenging for surgeons due to limited visibility and potential errors in cutting angles. This study investigated the effects of slight angle variations in the anterior-posterior slope of the lateral tibial tray. Results showed that a slight posterior slope during surgery can reduce the chances of implant instability.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)