Adult Stem Cell Therapeutics in Diabetic Retinopathy

Assessing “cell therapy” clinics offering treatments of ocular conditions using direct-to-consumer marketing websites in the United States

(2019) Rajinder S. Nirwan et al.   OPHTHALMOLOGY

Integral Hematologic Indices in the Evaluation of the Immunologic Reactivity of the Organism in a Patient With Complication of Type 1 Diabetes Mellitus: A Case of Diabetic Retinopathy After Autologous Mesenchymal Stem Cell Transplant

(2019) Manshuk Yeltokova et al.   Experimental and Clinical Transplantation

Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies

(2019) Nádia de Cássia Noronha et al.   Stem Cell Research & Therapy

Pathophysiology of Diabetic Retinopathy: Contribution and Limitations of Laboratory Research

(2019) Timothy S. Kern et al.   OPHTHALMIC RESEARCH

Stem cell-based retina models

(2018) Kevin Achberger et al.   ADVANCED DRUG DELIVERY REVIEWS

Decellularized matrix of adipose-derived mesenchymal stromal cells enhanced retinal progenitor cell proliferation via the Akt/Erk pathway and neuronal differentiation

(2018) Jing Ji et al.   CYTOTHERAPY

Mesenchymal stromal/stem cells as potential therapy in diabetic retinopathy

(2018) Agnese Fiori et al.   IMMUNOBIOLOGY

Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction

(2018) Yaqian Duan et al.   STEM CELLS

Efficacy and Safety of Autologous Bone Marrow Mesenchymal Stem Cell Transplantation in Patients with Diabetic Retinopathy

(2018) Xianliang Gu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human adipose tissue-derived stromal cells act as functional pericytes in mice and suppress high-glucose-induced proinflammatory activation of bovine retinal endothelial cells

(2018) Ghazaleh Hajmousa et al.   DIABETOLOGIA

Antioxidant preconditioning improves the paracrine responsiveness of bone marrow mesenchymal stem cells to diabetic wound fluid

(2018) Yashar Mehrbani Azar et al.   STEM CELLS AND DEVELOPMENT

Human Wharton’s jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors

(2018) Jose E. Millán-Rivero et al.   Scientific Reports

Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse

(2018) Sally L. Elshaer et al.   Stem Cell Research & Therapy

The influence of rAAV2-mediated SOX2 delivery into neonatal and adult human RPE cells; a comparative study

(2017) Razie Ezati et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vision Loss after Intravitreal Injection of Autologous “Stem Cells” for AMD

(2017) Ajay E. Kuriyan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Advances in bone marrow stem cell therapy for retinal dysfunction

(2017) Susanna S. Park et al.   PROGRESS IN RETINAL AND EYE RESEARCH

CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments

(2017) Niloofar Farhang et al.   TISSUE ENGINEERING PART A

Hematopoietic stem/progenitor involvement in retinal microvascular repair during diabetes: Implications for bone marrow rejuvenation

(2017) Ashay D. Bhatwadekar et al.   VISION RESEARCH

Preclinical Evaluation and Optimization of a Cell Therapy Using Human Cord Blood-Derived Endothelial Colony-Forming Cells for Ischemic Retinopathies

(2017) Emma Reid et al.   Stem Cells Translational Medicine

Diabetic retinopathy: new therapeutic perspectives based on pathogenic mechanisms

(2017) C. Hernández et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Therapeutic efficacy of neural stem cells originating from umbilical cord-derived mesenchymal stem cells in diabetic retinopathy

(2017) Wei Zhang et al.   Scientific Reports

Retinal Angiogenesis Effects of TGF-β1 and Paracrine Factors Secreted from Human Placental Stem Cells in Response to a Pathological Environment

(2016) Kyung-Sul Kim et al.   CELL TRANSPLANTATION

Update on the mechanisms of homing of adipose tissue–derived stem cells

(2016) Yong Zhao et al.   CYTOTHERAPY

Correction: Retinal Electrophysiological Effects of Intravitreal Bone Marrow Derived Mesenchymal Stem Cells in Streptozotocin Induced Diabetic Rats

(2016) Eren Çerman et al.   PLoS One

Hyperglycemia Induces Bioenergetic Changes in Adipose-Derived Stromal Cells While Their Pericytic Function Is Retained

(2016) Ghazaleh Hajmousa et al.   STEM CELLS AND DEVELOPMENT

Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice

(2016) Marcelo Ezquer et al.   Stem Cell Research & Therapy

LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

(2016) Yoolhee Yang et al.   Stem Cell Research & Therapy

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?

(2016) Ann De Becker et al.   World Journal of Stem Cells

Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy

(2016) Harshini Chakravarthy et al.   PLoS One

Neuroprotective effects of intravitreally transplanted adipose tissue and bone marrow–derived mesenchymal stem cells in an experimental ocular hypertension model

(2015) Esra Emre et al.   CYTOTHERAPY

Stem cell treatment of degenerative eye disease

(2015) Ben Mead et al.   Stem Cell Research

Adipose-Derived Stem Cells From Diabetic Mice Show Impaired Vascular Stabilization in a Murine Model of Diabetic Retinopathy

(2015) Stephen M. Cronk et al.   Stem Cells Translational Medicine

Regenerative Therapeutic Potential of Adipose Stromal Cells in Early Stage Diabetic Retinopathy

(2014) Gangaraju Rajashekhar et al.   PLoS One

Mesenchymal Stem Cells: New Players in Retinopathy Therapy

(2014) Gangaraju Rajashekhar   Frontiers in Endocrinology

Vascular Progenitors From Cord Blood–Derived Induced Pluripotent Stem Cells Possess Augmented Capacity for Regenerating Ischemic Retinal Vasculature

(2013) Tea Soon Park et al.   CIRCULATION

Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT)

(2013) Philippe Bourin et al.   CYTOTHERAPY

Transplantation of human bone marrow mesenchymal stem cells as a thin subretinal layer ameliorates retinal degeneration in a rat model of retinal dystrophy

(2013) Adi Tzameret et al.   EXPERIMENTAL EYE RESEARCH

Adverse events and complications associated with intravitreal injection of anti-VEGF agents: a review of literature

(2013) K Ghasemi Falavarjani et al.   EYE

Phenotypic characterization and in vivo localization of human adipose-derived mesenchymal stem cells

(2013) Young-Joon Ryu et al.   MOLECULES AND CELLS

Correction: Pericytes Derived from Adipose-Derived Stem Cells Protect against Retinal Vasculopathy

(2013) Thomas A. Mendel et al.   PLoS One

Diabetic retinopathy: pathogenesis, clinical grading, management and future developments

(2012) L. Z. Heng et al.   DIABETIC MEDICINE

In vitromigration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors

(2011) Sun Jin Baek et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Native human adipose stromal cells: localization, morphology and phenotype

(2011) M Maumus et al.   INTERNATIONAL JOURNAL OF OBESITY

Transient Inhibition of Transforming Growth Factor-β1 in Human Diabetic CD34+Cells Enhances Vascular Reparative Functions

(2010) Ashay D. Bhatwadekar et al.   DIABETES

Amelioration of diabetic retinopathy by engrafted human adipose-derived mesenchymal stem cells in streptozotocin diabetic rats

(2010) Zhikun Yang et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Carbon Monoxide and Nitric Oxide Mediate Cytoskeletal Reorganization in Microvascular Cells via Vasodilator-Stimulated Phosphoprotein Phosphorylation: Evidence for Blunted Responsiveness in Diabetes

(2008) S. Li Calzi et al.   DIABETES

Adipose-derived stem cells: Isolation, expansion and differentiation☆

(2008) B BUNNELL et al.   METHODS