Antitumor Effect of Pyrogallol via miR-134 Mediated S Phase Arrest and Inhibition of PI3K/AKT/Skp2/cMyc Signaling in Hepatocellular Carcinoma

Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment

(2019) Tengjiao Fan et al.   Cancers

Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway

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SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination

(2019) Ce Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Advances in inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy

(2019) Jia Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

7‐Deoxynarciclasine shows promising antitumor efficacy by targeting Akt against hepatocellular carcinoma

(2019) Shuangshuang Yin et al.   INTERNATIONAL JOURNAL OF CANCER

Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells

(2019) An-Chin Cheng et al.   JOURNAL OF MEDICINAL FOOD

Quercetin inhibits growth of hepatocellular carcinoma by apoptosis induction in part via autophagy stimulation in mice

(2019) Yi Ji et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

MicroRNA-134 inhibits osteosarcoma angiogenesis and proliferation by targeting the VEGFA/VEGFR1 pathway

(2018) Long Zhang et al.   FEBS Journal

The specific role of O6-methylguanine-DNA methyltransferase inhibitors in cancer chemotherapy

(2018) Guohui Sun et al.   Future Medicinal Chemistry

Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells

(2018) Nupoor Prasad et al.   JOURNAL OF BIOSCIENCES

The Role of Exportin-5 in MicroRNA Biogenesis and Cancer

(2018) Ke Wu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Induction of HT-29 Colon Cancer Cells Apoptosis by Pyrogallol with Growth Inhibiting Efficacy Against Drug Resistant Helicobacter pylori

(2018) Lukmanul Hakkim et al.   Anti-Cancer Agents in Medicinal Chemistry

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Decursin inhibits the growth of HepG2 hepatocellular carcinoma cells via Hippo/YAP signaling pathway

(2018) Jianchun Li et al.   PHYTOTHERAPY RESEARCH

Biochanin A Induces S Phase Arrest and Apoptosis in Lung Cancer Cells

(2018) Yan Li et al.   Biomed Research International

The potential of combi-molecules with DNA-damaging function as anticancer agents

(2017) Guohui Sun et al.   Future Medicinal Chemistry

Chemotherapy for hepatocellular carcinoma: current status and future perspectives

(2017) Masafumi Ikeda et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3

(2017) Yanqi Liu et al.   ONCOLOGY REPORTS

miR-134: A Human Cancer Suppressor?

(2017) Jing-Yu Pan et al.   Molecular Therapy-Nucleic Acids

Skp2 Inhibitors: Novel Anticancer Strategies

(2016) Yeongju Lee et al.   CURRENT MEDICINAL CHEMISTRY

Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination

(2016) Jason S. L. Yu et al.   DEVELOPMENT

MicroRNA-134 modulates glioma cell U251 proliferation and invasion by targeting KRAS and suppressing the ERK pathway

(2016) Yuguang Zhao et al.   TUMOR BIOLOGY

The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression

(2016) Jiandong Chen   Cold Spring Harbor Perspectives in Medicine

MicroRNA-134 regulates lung cancer cell H69 growth and apoptosis by targeting WWOX gene and suppressing the ERK1/2 signaling pathway

(2015) Tianjun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-134 modulates resistance to doxorubicin in human breast cancer cells by downregulating ABCC1

(2015) Lin Lu et al.   BIOTECHNOLOGY LETTERS

Treatment of Liver Cancer

(2015) Chun-Yu Liu et al.   Cold Spring Harbor Perspectives in Medicine

MicroRNA-134 suppresses endometrial cancer stem cells by targeting POGLUT1 and Notch pathway proteins

(2014) Yongtao Gao et al.   FEBS LETTERS

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Skp2 Expression and Activity and Its Role in Cancer Progression

(2011) Chia-Hsin Chan et al.   TheScientificWorldJOURNAL

The effects of MAPK inhibitors on pyrogallol-treated Calu-6 lung cancer cells in relation to cell growth, reactive oxygen species and glutathione

(2009) Yong Hwan Han et al.   FOOD AND CHEMICAL TOXICOLOGY

Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model

(2009) Chih-Jen Yang et al.   LUNG CANCER

Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells

(2008) Elena Nicolis et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pyrogallol Structure in Polyphenols is Involved in Apoptosis-induction on HEK293T and K562 Cells

(2008) Shinya Mitsuhashi et al.   MOLECULES