Article
Chemistry, Analytical
Asmaa Abu Sa'aleek, Anas Alshishani, Lena Shaghlil, Jameel S. Aljariri Alhesan, Yousef Al-ebini
Summary: A new method based on salting-out assisted liquid-liquid extraction (SALLE) coupled with HPLC-UV has been developed for the analysis of vitamin D3 in different pharmaceutical dosage forms. The method has been optimized in terms of chromatographic and extraction parameters, and validated in terms of selectivity, linearity, accuracy, LOD, LOQ, robustness, and stability. The results indicate that the SALLE method offers a simpler and more efficient approach for vitamin D3 determination, with low deviations compared to the conventional USP method.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Fu Wan, Cong Zhou, Afang Liu, Tiantai Kang, Pengcheng Liao, Shuping Liu, Shihui Si
Summary: Biological fermentation is an environmentally friendly method for producing 2,3-Butanediol (BDO), a potential alternative fuel. However, the extraction of BDO from the fermentation process is challenging and costly. In this study, nine acidic deep eutectic solvents (ADES) were used to create a salting-out liquid-liquid extraction system to separate BDO from aqueous solutions. The parameters affecting the extraction process were investigated, and under optimal conditions, a high extraction efficiency of over 92% was achieved. Additionally, the deep eutectic solvent was successfully recycled through pH adjustment, providing a sustainable and green method for BDO extraction.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Kenan Can Tok, Mehmet Gumustas, Ceyda Tuba Sengel-Turk, Gulin Amasya, Bilge Bayram, Ebru Arioglu-Inan
Summary: This study developed a polymeric nanoparticulate drug delivery system for piroxicam and developed a novel HPLC methodology for its determination. The developed method was successfully applied to analyze piroxicam in pharmaceutical preparations and biological samples without any interference.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Balint Samuel Szabo, Peter Pal Jakab, Janos Hegedus, Csaba Kirchkeszner, Noemi Petrovics, Zoltan Nyiri, Zsolt Bodai, Tamas Rikker, Zsuzsanna Eke
Summary: A new UHPLC-MS/MS method was developed to detect carcinogenic PAAs from food packaging materials, meeting the latest regulatory requirements. The combination of solid phase extraction with salting-out assisted liquid-liquid extraction effectively improved the enrichment factor of target compounds. Validation results demonstrated the method's suitability for daily routine analysis and compliance testing of food packaging materials according to the latest regulations.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Fadi Aldeek, Vanessa Lopez, John H. H. Miller
Summary: In this study, a new method was developed and validated for the extraction and quantification of nicotine from various commercially available oral tobacco products. The method showed high accuracy and precision, and was applicable for both traditional moist smokeless and oral tobacco-derived nicotine products. This method can be used for quality control and regulatory purposes in the tobacco industry.
Article
Chemistry, Analytical
Katerina Fikarova, Burkhard Horstkotte, Daniel Machian, Hana Sklenarova, Petr Solich
Summary: A new automated extraction procedure has been developed for the determination of four sulfonamides in urine, using a double-stage Lab-In-Syringe method coupled online to HPLC. The method improves both preconcentration factor and extract cleanup, reducing the total analysis time to 13.5 min, and achieving high recovery values for the analytes.
Article
Chemistry, Analytical
Fu Wan, Shuping Liu, Li Wang, Shihui Si
Summary: This study developed a new high-efficient sample preparation method for the determination of polar ethylene glycol and diethylene glycol in liquid samples. The method showed satisfactory analytical performances with good linearity and high recovery rates, and it was considered rapid and environmentally friendly due to its low solvent consumption.
MICROCHEMICAL JOURNAL
(2022)
Article
Food Science & Technology
Meng-Zhen Jia, Xiao-Qian Fu, Long Deng, Zhang-Lian Li, Yan-Yan Dang
Summary: This study aimed to develop an effective method for extracting total phenolic (TP) from grape seed using enzyme and microwave co-assisted salting-out extraction (EMASOE). By optimizing the extraction conditions, the maximum extraction yield of TP was obtained. HPLC analysis showed that EMASOE method extracted more types of monomer phenolic compounds with higher content compared to other extraction methods.
Article
Biochemical Research Methods
Ali K. Alshabrawy, Amanda Bergamin, Deepti K. Sharma, Shane M. Hickey, Doug A. Brooks, Peter O'Loughlin, Michael D. Wiese, Paul H. Anderson
Summary: LC-MS/MS method has been developed for simultaneous quantification of three vitamin D metabolites in human serum with satisfactory accuracy and precision. The method showed good stability and compared systematically with other quantitative methods with some differences.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Biochemical Research Methods
Suyang Duan, Yuesheng Dong, Yongping Xu, Jiajun Yin, Lili Geng, Zhilong Xiu
Summary: Phage phiAB9 for multidrug-resistant Acinetobacter baumannii was separated and purified by a simple and cost-saving one-step salting-out extraction (SOE) method. This method was found to be effective in removing impurities and achieving a high recovery rate of the phage.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Multidisciplinary
Fatemeh Norouzi, Afshin Gharekhani, Abolghasem Jouyban, Ali Shayanfar
Summary: A simple analytical method using salting-out assisted liquid-liquid extraction and spectrofluorimetry was developed for quantifying indoxyl sulfate (InS) in plasma. The method showed a linear range between 2.5 and 40 μg/ml with high accuracy and precision, making it suitable for quantifying InS in real plasma samples.
Article
Chemistry, Analytical
Vahid Alimoradi, Mohammad Reza Afshar Mogaddam, Mir Ali Farajzadeh, Mahboob Nemati, Farzaneh Lotfipour
Summary: In this study, surfactant-assisted deep eutectic solvent-based salting-out homogenous liquid-liquid extraction was introduced for the isolation of natamycin from fruit juices. The method showed low limits of determination and quantification, acceptable repeatability, and satisfactory extraction recovery.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Sercan Yildirim, Katerina Fikarova, Veronika Pilarova, Lucie Novakova, Petr Solich, Burkhard Horstkotte
Summary: A sample preparation method was developed for the determination of beta-blockers in serum, which involves protein precipitation and salting-out homogenous liquid-liquid extraction. The entire procedure was automated using a computer-controlled syringe pump. The method is based on denaturation of serum proteins with acetonitrile and salt-induced phase separation. The extract is then separated and diluted in-syringe before analysis using UHPLC-MS/MS. The method has a high sample throughput and provides accurate and precise results.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Jianing Zhang, Fengjie Yu, Yunmin Tao, Chunping Du, Wenchao Yang, Wenbin Chen, Xijuan Tu
Summary: A novel sample preparation method, mu-SOA-MSPD, was developed for the determination of bisphenol contaminants in bee pollen. This method combines MSPD and HLLE to simplify and speed up the preparation process, showing excellent clean-up ability in removing matrix components.
Article
Chemistry, Applied
Anna Rozanska, Magdalena Fabjanowicz, Kaja Kalinowska, Zaneta Polkowska, Justyna Plotka-Wasylka
Summary: Salting-out assisted liquid-liquid microextraction (SALLME) was combined with derivatization procedure to establish a one-step sample pre-treatment approach for rapid analysis of 14 biogenic amines (BAs) in fruit juices. The developed method exhibited satisfactory analytical performance and was suitable for analysis of different berry juice samples.
Article
Food Science & Technology
Rouhollah Heydari, Rezvan Feyzianpour
Summary: A simple, fast, and effective salt-assisted liquid-liquid extraction (SALLE) technique coupled with high-performance liquid chromatography (HPLC) was developed for determination of 2,4-dichlorophenoxyacetic acid (2,4-D) in water and edible seeds samples. The method successfully extracted the target analyte with good linearity, precision, and recovery rates under optimized experimental conditions.
FOOD ANALYTICAL METHODS
(2021)
Article
Food Science & Technology
Samaneh Tavakolian, Hamed Ahari, Mohammad Hadi Givianrad, Hedayat Hosseini
Summary: The study demonstrates that nanocomposite films containing Al2O3@SiO2 and Al2O3@TiO2 nanoparticles can significantly regulate moisture absorption, water vapor permeability, and gas transmission rate, thus enhancing the performance of food packaging systems.
FOOD AND BIOPROCESS TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Mohammad Moradi, Sanaz Zarabi, Rouhollah Heydari
Summary: This study compared two extraction methods for simultaneous preconcentration and spectrophotometric determination of Sb(III) and Sb(V) species in water and plasma samples. The results showed that the NT-DLLME method had higher sensitivity and lower detection and quantitation limits under optimized conditions.
Article
Environmental Sciences
Yeganeh Kosar Hashemi, Mohammad Tavakkoli Yaraki, Sina Ghanbari, Leily Heidarpoor Saremi, Mohammad Hadi Givianrad
Summary: Visible-light driven photocatalysts play a significant role in wastewater treatment. A fluorine and nitrogen co-doped titanium dioxide/silica nanocomposite with high surface area and narrow band gap was successfully synthesized as a potential candidate for photocatalytic applications under visible light. Systematic density functional theory calculations were conducted to understand the effect of dopant atoms on the band gap of TiO2 nanoparticles. The study demonstrated the successful removal of organic water pollutants by carefully controlling operational parameters and using highly efficient photocatalytic nanomaterials.
Article
Chemistry, Analytical
Sima Khiltash, Rouhollah Heydari, Majid Ramezani
Summary: A nanocomposite sorbent of graphene oxide/polydopamine-polyacrylamide was synthesised for dispersive micro-solid phase extraction of diazinon, coupled with HPLC-UV detector. The method was characterised by various analytical techniques and optimised for key parameters, achieving a method detection limit of 0.24 ng/mL and relative recovery data within 82.0-98.0% for real samples. The proposed method was successfully applied to quantitative determination of diazinon in environmental and food samples.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Review
Food Science & Technology
Peiman Esmaeilzadeh, Mohammad Reza Ehsani, Maryam Mizani, Mohammad Hadi Givianrad
Summary: The study analyzed the characteristics of Kope cheese during a ripening period of 187 days, focusing on factors such as chemical composition, fatty acids, organic acids, volatile compounds, and sensory attributes. Protein content, pH, salt content, and water activity were found to be closely correlated with sensory properties and led to distinct groups based on ripening stages. The study also identified the key volatile compounds and sensory attributes associated with early, medium, and old-ripened cheeses.
JOURNAL OF FOOD SCIENCE
(2021)
Article
Engineering, Chemical
Maryam Danesh-khorasgani, Hossein Faghihian, Mohammad Hadi Givianrad, Parviz Aberoomand-Azar, Mohammad Saber-Tehrani
Summary: A novel sorbent was synthesized and proved to be effective in adsorbing heavy metal cations such as lead, chromium, cadmium, and cobalt. The optimized adsorption capacities for the studied cations were determined to be 242.50, 214.72, 187.86, and 166.46 mg/g. The adsorption process was fast and equilibrium was reached within a relatively short time. The adsorbent could be regenerated and reused without significant loss of adsorption capacity.
ADVANCED POWDER TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Sanaz Zarabi, Rouhollah Heydari, Sayed Zia Mohammadi
Summary: The new version of dispersive micro-solid phase extraction in a micro-channel system was developed for the first time, showing higher extraction efficiency compared to conventional methods. Various parameters were optimized, leading to a linear method with good detection limits. The validated method was successfully applied for determining ibuprofen in plasma samples, demonstrating its potential for future research.
MICROCHEMICAL JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Golshan Moradi, Rouhollah Heydari, Sirus Zinadini, Masoud Rahimi, Foad Gholami
Summary: In this study, T-KIT-6 mesoporous was synthesized and used to prepare a nanofiltration membrane with high efficiency in removing dyes, salts, and heavy metal ions. The membrane exhibited excellent performance, low irreversible fouling ratio, high flux recovery ratio, and long-term stability. These results indicate a promising economic and efficient technology for wastewater treatment.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Chemistry, Analytical
Mohsen Heydarzadeh, Rouhollah Heydari
Summary: In this research, 2,4-dichlorophenoxyacetic acid was determined using a salt-assisted liquid-liquid extraction in a micro-channel. The extraction efficiency was optimized by investigating factors like extraction solvent, salt amount, pH, micro-channel shape, length, and inside diameter. The proposed method showed improved efficiency compared to conventional salt-assisted extraction, and was successfully applied to environmental and vegetable samples.
SEPARATION SCIENCE PLUS
(2022)
Article
Chemistry, Analytical
Fatemeh Parvizi, Arsalan Parvareh, Rouhollah Heydari
Summary: Modified nanomaterials are used to fabricate a hydrophobic polyethersulfone (PES) membrane for liquid phase microextraction (LPME) in a microfluidic device. The membrane's surface is modified by depositing modified boehmite nanoparticles using a dip-coating method. The modified membrane shows a switch from hydrophilic to hydrophobic behavior and demonstrates improved performance in LPME compared to the commercial membrane.
MICROCHEMICAL JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Azam Sadat Beheshtian, Mohammad Hadi Givianrad, Hossain-Ali Rafiee-Pour, Parviz Aberoomand Azar
Summary: This study presents the green synthesis of copper oxide nanoparticles using Malva sylvestris extract. The Ms-CuO NPs exhibited monoclinic crystalline phases and had an average size of 16.28 nm. The Ms-CuO/CPE electrode modified with Ms-CuO NPs showed excellent electrochemical response for the detection of Quercetin.
OPTICAL AND QUANTUM ELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Maryam Majidi, Mohammad Hadi Givianrad, Mohammad Saber-Tehrani, Parviz Aberoomand Azar
Summary: Porous graphitic carbon nitride (g-C3N4) nanosheets with carbon vacancies were synthesized through recalcination of bulk g-C3N4 at 550 degrees C for 2 hours in a muffle furnace. The synthesized product (RCN) was characterized using various techniques and its photoactivity efficiency was evaluated for dye degradation. The results showed that RCN, in the presence of OH- anions, can efficiently degrade the tested dyes under visible light.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Golshan Moradi, Rouhollah Heydari, Sirus Zinadini, Masoud Rahimi
Summary: This study prepared a high-performance thin film composite (TFC) nanofiltration (NF) membrane for antibiotic removal and pharmaceutical wastewater treatment by furosemide-modified chitosan (CS@FS) composite assisted pectin (PC) functionalization of the polyethersulfone (PES) NF membrane. The CS@FS-co-PC TFC membranes showed improved physicochemical characteristics and separation performance, with high rejection rates for antibiotics and effective removal of pharmaceutical wastewater contaminants. The optimized TFC-0.5 membrane achieved high flux, recovery ratio, and resistance to fouling.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Maryam Danesh-Khorasgani, Hossein Faghihian, Mohammad Hadi Givianrad, Parviz Aberoomand-Azar, Mohammad Saber-Tehrani
Summary: A new adsorbent synthesized from SBA-15 modified with 1,5-diphenyl carbazide was used to extract cadmium from aquatic systems. Under optimized conditions, it achieved an adsorption capacity of 160mg/g, with a fast equilibrium time of 25.39 min. The regenerated sorbent was successfully reused without significant loss of adsorption capacity, and the experimental data fit well with the Langmuir model.
COMPTES RENDUS CHIMIE
(2021)
