The renin-angiotensin-aldosterone system: a crossroad from arterial hypertension to heart failure

Interactive role of diastolic dysfunction and ventricular remodeling in asymptomatic subjects at increased risk of heart failure

(2019) Iacopo Fabiani et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Brain Natriuretic Peptide and Its Biochemical, Analytical, and Clinical Issues in Heart Failure: A Narrative Review

(2018) Shihui Fu et al.   Frontiers in Physiology

2018 ESC/ESH Guidelines for the management of arterial hypertension

(2018) Bryan Williams et al.   EUROPEAN HEART JOURNAL

The renin–angiotensin system in cardiovascular autonomic control: recent developments and clinical implications

(2018) Amanda J. Miller et al.   CLINICAL AUTONOMIC RESEARCH

Sacubitril/valsartan and low blood pressure in heart failure with reduced ejection fraction

(2017) Rosa Maria Bruno et al.   EUROPEAN HEART JOURNAL

2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure

(2017) Clyde W. Yancy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Heart Failure and Hypertension

(2017) Marc A. Pfeffer   MEDICAL CLINICS OF NORTH AMERICA

Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction

(2017) Scott D. Solomon et al.   JACC-Heart Failure

The Transition From Hypertension to Heart Failure

(2017) Franz H. Messerli et al.   JACC-Heart Failure

Predicting Heart Failure With Preserved and Reduced Ejection FractionCLINICAL PERSPECTIVE

(2016) Jennifer E. Ho et al.   Circulation-Heart Failure

Heart failure with preserved ejection fraction in hypertension

(2016) Loon Yee Louis Teo et al.   CURRENT OPINION IN CARDIOLOGY

Aldosterone in vascular and metabolic dysfunction

(2016) James M. Luther   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

(2016) Piotr Ponikowski et al.   EUROPEAN HEART JOURNAL

Chronic heart failure as a state of reduced effectiveness of the natriuretic peptide system: implications for therapy

(2016) Javier Díez   EUROPEAN JOURNAL OF HEART FAILURE

The neprilysin pathway in heart failure: a review and guide on the use of sacubitril/valsartan

(2016) Pardeep S Jhund et al.   HEART

Effects of blood pressure-lowering treatment. 6. Prevention of heart failure and new-onset heart failure – meta-analyses of randomized trials

(2016) Costas Thomopoulos et al.   JOURNAL OF HYPERTENSION

When an Increase in Central Systolic Pressure Overrides the Benefits of Heart Rate Lowering

(2016) Franz H. Messerli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers in Patients Without Heart Failure? Insights From 254,301 Patients From Randomized Trials

(2016) Sripal Bangalore et al.   MAYO CLINIC PROCEEDINGS

Hypertension: Renin-Angiotensin-Aldosterone System Alterations

(2015) L. te Riet et al.   CIRCULATION RESEARCH

Blood pressure and prognosis in patients with incident heart failure: the Diet, Cancer and Health (DCH) cohort study

(2015) Gregory Y. H. Lip et al.   Clinical Research in Cardiology

Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials

(2015) Chirag Bavishi et al.   EUROPEAN HEART JOURNAL

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

(2015) Bryan Williams et al.   LANCET

Direct Role for Smooth Muscle Cell Mineralocorticoid Receptors in Vascular Remodeling: Novel Mechanisms and Clinical Implications

(2014) Jenny B. Koenig et al.   CURRENT HYPERTENSION REPORTS

Trends in Hypertension Prevalence, Awareness, Treatment, and Control Among US Adults 80 Years and Older, 1988-2010

(2014) Samantha G. Bromfield et al.   Journal of Clinical Hypertension

Spironolactone for Heart Failure with Preserved Ejection Fraction

(2014) Bertram Pitt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Meta-analysis: β-Blocker Dose, Heart Rate Reduction, and Death in Patients With Heart Failure

(2013) Finlay A. McAlister   ANNALS OF INTERNAL MEDICINE

Effects of Neutral Endopeptidase (Neprilysin) Inhibition on the Response to Other Vasoactive Peptides in Small Human Resistance Arteries: Studies with Thiorphan and Omapatrilat

(2013) Jonathan R. Dalzell et al.   Cardiovascular Therapeutics

Aldosterone Mediates Cardiac Fibrosis in the Setting of Hypertension

(2013) Feriel Azibani et al.   CURRENT HYPERTENSION REPORTS

Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact

(2013) John J. V. McMurray et al.   EUROPEAN JOURNAL OF HEART FAILURE

Salt, the renin–angiotensin–aldosterone system and resistant hypertension

(2013) Tatsuo Shimosawa   HYPERTENSION RESEARCH

Effect of Aliskiren on Postdischarge Mortality and Heart Failure Readmissions Among Patients Hospitalized for Heart Failure

(2013) Mihai Gheorghiade et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary

(2013) Clyde W. Yancy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Novel Paradigm for Heart Failure With Preserved Ejection Fraction

(2013) Walter J. Paulus et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Agonist-Independent Constitutive Activity of Angiotensin II Receptor Promotes Cardiac Remodeling in Mice

(2012) Noritaka Yasuda et al.   HYPERTENSION

Aldosterone Acting Through the Central Nervous System Sensitizes Angiotensin II-Induced Hypertension

(2012) Baojian Xue et al.   HYPERTENSION

Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats

(2012) Toshiaki Nakagaki et al.   HYPERTENSION RESEARCH

Cardiorenal Syndrome Type 1

(2012) Claudio Ronco et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vascular Actions of Aldosterone

(2012) Marie Briet et al.   JOURNAL OF VASCULAR RESEARCH

The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial

(2012) Scott D Solomon et al.   LANCET

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

(2012) Amy McCurley et al.   NATURE MEDICINE

Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes

(2012) Hans-Henrik Parving et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of the direct renin inhibitor aliskiren on left ventricular remodelling following myocardial infarction with systolic dysfunction

(2011) Scott D. Solomon et al.   EUROPEAN HEART JOURNAL

Abnormal haemodynamic response to exercise in heart failure with preserved ejection fraction

(2011) Paul S. Bhella et al.   EUROPEAN JOURNAL OF HEART FAILURE

GPR30 Expression Is Required for the Mineralocorticoid Receptor–Independent Rapid Vascular Effects of Aldosterone

(2011) Robert Gros et al.   HYPERTENSION

Angiotensin II Increases Activity of the Epithelial Na+Channel (ENaC) in Distal Nephron Additively to Aldosterone

(2011) Mykola Mamenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Left Ventricular Structural Remodeling in Health and Disease

(2011) William H. Gaasch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

(2011) C.M. O'Connor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trials on the Effect of Cardiac Resynchronization on Arterial Blood Pressure in Patients With Heart Failure

(2010) Sameer Ather et al.   AMERICAN JOURNAL OF CARDIOLOGY

Cardiorenal Syndrome

(2010) Jeremy S. Bock et al.   CIRCULATION

Epidemiology and clinical course of heart failure with preserved ejection fraction

(2010) Carolyn S.P. Lam et al.   EUROPEAN JOURNAL OF HEART FAILURE

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

(2010) Karl Swedberg et al.   LANCET

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Relation of Disease Pathogenesis and Risk Factors to Heart Failure With Preserved or Reduced Ejection Fraction

(2009) Douglas S. Lee et al.   CIRCULATION

A Summary of the ADVANCE Trial

(2009) S. R. Heller et al.   DIABETES CARE

Effects of Carperitide on the Long-Term Prognosis of Patients With Acute Decompensated Chronic Heart Failure

(2008) Noritake Hata et al.   CIRCULATION JOURNAL

Effects of the Oral Direct Renin Inhibitor Aliskiren in Patients With Symptomatic Heart Failure

(2008) John J.V. McMurray et al.   Circulation-Heart Failure

The Role of Mineralocorticoid Receptor Expression in Brain Remodeling after Cerebral Ischemia

(2008) Naofumi Oyamada et al.   ENDOCRINOLOGY

Safety and Tolerability of Angiotensin-Converting Enzyme Inhibitor Versus the Combination of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker in Patients With Left Ventricular Dysfunction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2008) Rachid Lakhdar et al.   JOURNAL OF CARDIAC FAILURE

Beta-Blockers for Primary Prevention of Heart Failure in Patients With Hypertension

(2008) Sripal Bangalore et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Treatment of Hypertension in Patients 80 Years of Age or Older

(2008) Nigel S. Beckett et al.   NEW ENGLAND JOURNAL OF MEDICINE

Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction

(2008) Barry M. Massie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Angiotensin Type 2 Receptor Overexpression in the Rostral Ventrolateral Medulla on Blood Pressure and Urine Excretion in Normal Rats

(2007) Lie Gao et al.   HYPERTENSION