Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases

Title
Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases
Authors
Keywords
Nucleoside, Respiratory syncytial virus, Mitochondria, DNA polymerase γ, Mitochondrial RNA polymerase
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 25, Issue 12, Pages 2484-2487
Publisher
Elsevier BV
Online
2015-05-03
DOI
10.1016/j.bmcl.2015.04.073

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