4.6 Article

Cytotoxic glycosides from the roots of Weigela x Bristol Ruby

Journal

FITOTERAPIA
Volume 137, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.fitote.2019.104242

Keywords

Weigela x Bristol Ruby; Caprifoliaceae; Oleanolic acid glycosides; NMR; Cytotoxicity

Funding

  1. Vietnamese Government [911]
  2. (Vietnamese Government Scholarship)

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Seven oleanane-type glycosides were extracted and isolated by various chromatographic methods from the roots of Weigela x Bristol Ruby (1-7), six previously undescribed (1-6) and a known one (7). Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESIMS). Selected triterpenoid glycosides (1-3, 6, 7) displayed a good cytotoxic activity against a mouse colon cancer cell line CT26.

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