Article
Zoology
Rachanida Praparatana, Siriluk Maskaew, Ratiporn Thongsoi, Phanthipha Runsaeng, Prapaporn Utarabhand
Summary: FmGal, a galectin from Fenneropenaeus merguiensis, participates in shrimp immune response and is up-regulated upon infection with pathogens. It exhibits specific sugar specificity and enhances the phagocytosis and encapsulation ability of shrimp hemocytes towards pathogens.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2022)
Article
Fisheries
Yunqi Zhong, Zihao He, Xinxin Long, Danqing Hou, Xianye Hu, Chengbo Sun
Summary: Due to the destruction of the culture environment and serious ecological pressure, harmful metabolites such as ammonia nitrogen and nitrite accumulate in aquaculture ponds. Therefore, a strain called XA19, identified as Vibrio proteolyticus, was isolated for efficient nitrite removal. The strain showed resistance to multiple antibiotics and caused mortality in Fenneropenaeus merguiensis. Transcriptome sequencing analysis revealed differentially expressed genes related to immune response and metabolic pathways. This study provides insights into the toxicity, drug sensitivity, and immune response to V. proteolyticus infection.
JOURNAL OF FISH DISEASES
(2023)
Article
Fisheries
Linxin Dai, Zhiwang Xiong, Danqing Hou, Yue Wang, Ting Li, Xinxin Long, Haozhen Chen, Chengbo Sun
Summary: This research reported the isolation of a dominant bacteria strain V. owensii from a shrimp tank and its impact on the immune response of F. merguiensis. Drug susceptibility tests showed antibiotic resistance in V. owensii. LC50 tests revealed the toxicity of V. owensii to F. merguiensis. Transcriptomic analysis identified differentially expressed genes (DEGs) related to metabolism and immune pathways during V. owensii infection. The study provides valuable insights into the immune response mechanisms of F. merguiensis to V. owensii infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Po-Tsang Lee, Jing Huang, Chin-Yi Huang, Zi-Xuan Liu, Han-Yang Yeh, Huai-Ting Huang, Li-Li Chen, Fan-Hua Nan, Meng-Chou Lee
Summary: The study demonstrates that phycoerythrin from Colaconema sp. can act as an immunomodulator in whiteleg shrimp, enhancing immune gene expression and innate immune parameters to increase survival rates when challenged with viruses or bacteria.
Article
Fisheries
Ratiporn Thongsoi, Siriluk Maskaew, Panumas Puechpon, Benjaporn Noppradit, Napassawan Inaek, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: In this study, a PPAE gene called FmPPAE1 was cloned and analyzed in banana shrimp. FmPPAE1 plays a vital role in regulating the proPO system, exhibits antibacterial properties, and contributes to the suppression of bacterial proliferation.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Ecology
Lulu Chen, Dan Tang, Yuyan Hua, Xinyu Wang, Yanxuan Li, Zhengfei Wang
Summary: Global warming poses a challenge to animal health, as it leads to increased susceptibility to diseases caused by immune suppression during summer. However, research on the Toll-like receptor (TLR) gene family in decapod crustaceans lacks systematic naming, and the relationship between pathogen immunity adaptation and adaptive evolution of immune-related genes remains unclear. This study collected TLR gene sequences in decapod crustaceans and identified ten FcTLR genes in Fenneropenaeus chinensis. Further analyses revealed the structural characteristics, evolutionary patterns, and expression profiles of these genes. The results provide insights into the immune response and adaptive evolution of TLRs in decapod crustaceans to combat environmental damage.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2023)
Article
Fisheries
Ngoc Tuan Tran, Huifen Liang, Jinkun Li, Taoqiu Deng, Md Akibul Hasan Bakky, Ming Zhang, Shengkang Li
Summary: Innate immunity is crucial for protecting crustaceans against pathogens, especially the serious white spot syndrome virus (WSSV). Understanding how hosts respond to WSSV infection is essential for prevention and control. This review summarizes the involvement of signaling pathways and cellular activities in the immune response of crustaceans during WSSV infection, providing important insights into host-pathogen interaction and potential strategies for enhancing immune defense.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Yunfei Zhang, Chongyang Xiao, Fei Zhu
Summary: The study showed that dietary supplementation of 40 mg/kg quercetin significantly reduced crayfish mortality and WSSV copy number after challenge, while also increasing the immune activity such as catalase and lysozyme. Additionally, dietary quercetin enhanced the expression of immune-related genes and induced apoptosis in hemocytes of crayfish.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Hongtao Liu, Shengtao Guo, Rong Wang, Yugui He, Qiong Shi, Zhaobin Song, Mingqiu Yang
Summary: The study used proteomic sequencing of hepatopancreas in Vibrio harveyi-infected whiteleg shrimp and found a significant number of DEPs, specifically showing changes in the expression levels of C-type lectins after infection. Different members of the CTL family exhibit varied responses to Vibrio harveyi infection, suggesting potential differential functions and providing theoretical guidance for further research on immune responses and pathogen infections in shrimps.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Isis Rojas, Claudia Carcamo, Felipe Stambuk, Luis Mercado, Rodrigo Rojas, Paulina Schmitt, Katherina Brokordt
Summary: The study investigated the expression patterns of immune system genes during early development of scallop larvae. Results indicated a maturation of the immune system towards late developmental stages and a possible parental transfer of immune-related protein ApBD1.
Article
Fisheries
Xiujuan Zhou, Jing Gong, Yue Zhuang, Fei Zhu
Summary: The study found that coumarin can enhance the immunity of Cherax quadricarinatus, reduce the number of WSSV infections, and delay the infection process. Coumarin also has a positive effect on important immune parameters such as THC, ACP activity, SOD activity, lysozyme activity, and PO activity.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Sirawich Limkul, Tannatorn Phiwthong, Amarin Massu, Phattarunda Jaree, Jumroensri Thawonsuwan, Neung Teaumroong, Surintorn Boonanuntanasarn, Kunlaya Somboonwiwat, Pakpoom Boonchuen
Summary: The Vago interferon-like protein in shrimp plays a crucial role in antiviral and antimicrobial responses against pathogens. Specific isoforms of Vago activate immune pathways, including JAK/STAT, Toll/IMD, and proPO, to reduce mortality and enhance survival in shrimp infected with highly invasive viruses and bacteria. The findings suggest a cross-talk between Vago's antiviral and antimicrobial responses in shrimp immunity.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Ting Kang, Yanting Xia, Taiwei Dong, Xiaoyuan Zheng, Shun Yang, Shichao Qian, Mengmeng Huang, Hui Fei
Summary: A new C-type lectin, PtCTL-9, was identified from swimming crab and showed broad non-self immunity, acting as an opsonin to promote phagocytosis and hemocyte encapsulation. The QPN motif was found to be important for PtCTL-9's immune function.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Fisheries
Ying Huang, Ying Jiang, Miao-Miao Wang, Min-Yi Chen, Huan-Gen Chen, Heng-Yuan Chen, Wen-Jie Liu, Xiao-Rui Li, Xiao-Lei Han
Summary: This study cloned and characterized a mannose-binding lectin (MBL) called PcMBL from the crayfish Procambarus clarkii. PcMBL plays important roles in nonself recognition and clearance of invading microorganisms. It was found that PcMBL can influence the transcription of antimicrobial peptide genes and has the ability to bind to various microorganisms and carbohydrates. Furthermore, recombinant PcMBL can facilitate bacterial clearance, inhibit biofilm formation and growth, and reduce mortality in infected crayfish.
AQUACULTURE REPORTS
(2023)
Article
Fisheries
Chao Zhao, Chao Peng, Pengfei Wang, Bo Zhang, Lulu Yan, Chun-Lin Wang, Lihua Qiu
Summary: In this study, a novel TRIM37 homolog called PmTRIM37 was identified, which plays important roles in regulating innate immune processes, particularly antiviral and proinflammatory cytokine responses. PmTRIM37 is highly expressed in immune-related tissues and its expression is up-regulated after white spot syndrome virus (WSSV) infection. Knockdown of PmTRIM37 promotes WSSV replication and VP28 expression, suggesting its negative role in WSSV infection. Furthermore, PmTRIM37 positively regulates the NF-κB pathway and Antimicrobial peptides (AMP) expression during WSSV infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Entomology
Qilin Li, Mengge Li, Mengyao Zhu, Jielai Zhong, Liang Wen, Jie Zhang, Ruonan Zhang, Qiang Gao, Xiao-Qiang Yu, Yuzhen Lu
Summary: Cadherin, aminopeptidase N (APN) and alkaline phosphatase (ALP) have been identified as Cry receptors, with multiple paralogs found in ALPs and APNs. Different insects show sensitivity or insensitivity to Bt toxins based on the presence or absence of BtR orthologs. The expression levels of BtR and Cad89D-like genes are highly correlated with Cry toxin sensitivity in larvae of certain insect species.
Article
Entomology
Jie Zhang, Mengyao Zhu, Qilin Li, Ting Tang, Liang Wen, Jielai Zhong, Ruonan Zhang, Xiao-Qiang Yu, Yuzhen Lu
Summary: bHLH transcription factors play crucial roles in various metabolic and developmental processes in eukaryotes, and this study investigated their response to different pathogens in the polyphagous insect, Spodoptera litura. The research identified a new bHLH gene specific to Lepidoptera, analyzed the expression profiles of bHLH genes in response to pathogens, and highlighted the downregulation of SlbHLHs in the midgut of S. litura larvae after Bacillus thuringiensis treatment. These findings provide insights into the host-pathogen interaction mechanism mediated by bHLH members.
Article
Green & Sustainable Science & Technology
Khachonphong Nopphakat, Phanthipha Runsaeng, Lompong Klinnawee
Summary: This study identified Acaulospora fungi as the core AMF in rainfed lowland rice paddies and demonstrated their symbiotic roles in rice. Acaulospora spores can enhance phosphate accumulation in mycorrhizal roots and increase soil phosphorus availability through the secretion of acid phosphatase. However, inoculation with Acaulospora spores suppressed the growth of rice seedlings.
Editorial Material
Immunology
Liang Jiang, Xiao-Qiang Yu, Luc Swevers
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Pattamaporn Kwankaew, Naeem Madsari, Ratiporn Thongsoi, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: This study partially characterized the function of FmclipSP and demonstrated its association with VP28. The results indicate the importance of FmclipSP in the innate immunity of F. merguiensis.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Fisheries
Naeem Madsari, Siriluk Maskaew, Sumalee Obchoei, Pattamaporn Kwankaew, Wilaiwan Senghoi, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: This study investigated the application of the serine protease gene of Vibrio parahaemolyticus as a DNA vaccine in Litopenaeus vannamei. The DNA vaccine was found to stimulate the immune system in shrimp, leading to upregulated expression of immune-responsive genes and enhanced immune responses. The results suggest that the serine protease could be a virulence determinant and that the DNA vaccine has potential as a candidate for controlling acute hepatopancreatic necrosis disease in shrimp.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Zoology
Rachanida Praparatana, Siriluk Maskaew, Ratiporn Thongsoi, Phanthipha Runsaeng, Prapaporn Utarabhand
Summary: FmGal, a galectin from Fenneropenaeus merguiensis, participates in shrimp immune response and is up-regulated upon infection with pathogens. It exhibits specific sugar specificity and enhances the phagocytosis and encapsulation ability of shrimp hemocytes towards pathogens.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2022)
Article
Entomology
Ruonan Zhang, Xue Chen, Yuan Wang, Xu Bai, Qiong Yang, Yangjin Zhong, Xiao-Qiang Yu, Fengliang Jin, Wanying Yang
Summary: 20E is involved in larval molting, metamorphosis, and innate immune response in insects. It regulates AMP genes through the IMD pathway in Drosophila, but its involvement in other immune pathways is unknown. This study shows that BmMD-2A is regulated by 20E and activates downstream immune effectors to combat bacterial infections during larval metamorphosis in Bombyx mori.
Article
Entomology
Luoluo Wang, Zhichang Pang, Qi Chen, Zhentao Song, Yi Lu, Meng Yang, Jia Huang, Xiao-Qiang Yu, Xiaoyun Wang
Summary: This study analyzed the sublethal exposure of the bioinsecticide spinetoram to Aedes aegypti larvae and its effects on adult performance and susceptibility to dengue virus infection. The surviving adult mosquitoes exhibited smaller size and weaker blood-feeding capacity, as well as transgenerational sublethal effects on offspring survival rates. Additionally, surviving adult females had higher viral loads of dengue virus after spinetoram exposure. Mechanistically, inhibition of oxidative phosphorylation may stimulate dengue virus production in adult Ae. aegypti.
Article
Microbiology
Ugyen Wangmo Tenzin, Nuttapol Noirungsee, Phanthipha Runsaeng, Prakrit Noppradit, Lompong Klinnawee
Summary: The use of arbuscular mycorrhizal fungi (AMF) as biofertilizer is a sustainable approach to fertilization. Co-cultivating multiple host plants increases the production of AMF spores, but does not better sustain native AMF community compositions.
Article
Entomology
Yaqing Chen, Yushan Lai, Runzhou Liu, Lin Yao, Xiao-Qiang Yu, Xiaoyun Wang
Summary: In this study, the role of RNA m(6)A epigenetic regulation in the embryonic development of Spodoptera frugiperda was analyzed. The highly conserved function of m(6)A methyltransferases SfrMETTL3 and SfrMETTL14 among insects and mammals was discovered. Transcriptome-wide analysis revealed differential expression of m(6)A-modified transcripts in 2-hour and 24-hour embryos, with enrichment in genes related to cell and organ development. Moreover, it was found that RNA m(6)A methylation may regulate the transcriptional levels of genes related to tissue and organ development during the embryonic stage. This study provides new insights into the embryonic development of insects.
Article
Agronomy
Liang Jin, Bin-Wu Zhang, Jing-Wen Lu, Jun-Ao Liao, Qi-Jun Zhu, Yi Lin, Xiao-Qiang Yu
Summary: This study investigated the role of Buchnera-derived PFKA in Cry41-related toxicity against M. persicae. The results suggest that Cry41-related toxin interacts with Buchnera-derived PFKA to inhibit its enzymatic activity, likely impair cell viability, resulting in a decrease in the number of Buchnera and finally leading to M. persicae death.
PEST MANAGEMENT SCIENCE
(2023)
Review
Agronomy
Yuzhen Lu, Xinyue Deng, Qijun Zhu, Denghui Wu, Jielai Zhong, Liang Wen, Xiaoqiang Yu
Summary: RNA interference (RNAi) is a widely used method for silencing genes in various organisms and has been developed as a novel pest management strategy. Different delivery methods, such as microinjection, ingestion, soaking, oral and topical delivery, have been used for gene silencing in insect pests. Various genes involved in different processes can be targeted using RNAi, and RNAi-based pesticides have been developed in the form of genetically modified crops or as foliar sprays.
Article
Entomology
Qihao Hu, Yanhong Xiao, Runnan Wei, Ting Tang, Liang Wen, Yuzhen Lu, Xiao-Qiang Yu
Summary: This study identified a testis-specific gene CG3526 in Drosophila melanogaster and found that it plays a key role in spermatogenesis. The results suggest that CG3526 is a downstream effector gene in the JAK-STAT signaling pathway.
Article
Agriculture, Multidisciplinary
Jie Zhang, Siyu Wu, Yingjie Wen, Duo Lai, Shizi Kuang, Ruonan Zhang, Xiaoxia Xu, Fengliang Jin, Hanhong Xu, Xiao-Qiang Yu, Xuehua Shao
Summary: In this study, it is found that Eurycomanone (EN) is an active compound that inhibits the growth of Spodoptera frugiperda larvae by targeting the IIS pathway and activating the transcription factor SfFoxO. EN induces program cell death (PCD) in the larvae midgut and has potential as a botanical pesticide by targeting the insulin receptor and inhibiting the IIS signaling pathway.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)