Article
Agriculture, Dairy & Animal Science
Chen Ying, Wu Yangsheng, Lin Jiapeng, Wang Liqin, Li Xiaolin, Liu Mingjun, Huang Juncheng
Summary: Pre-pubertal females produce more oocytes but with lower developmental potential compared to adult animals. Oocyte quality is influenced by abnormal gene expression. This study identified differentially expressed genes in lamb oocytes after in vitro maturation using RNA sequencing technology, shedding light on the decreased developmental potential of lamb oocytes.
REPRODUCTION IN DOMESTIC ANIMALS
(2021)
Editorial Material
Immunology
Shiv Pillai
Summary: Repeated doses of mRNA vaccines for COVID-19 result in an increase of IgG4 antibodies, which can neutralize the virus and form mixed immune complexes with IgG1. However, pure IgG4 may be less effective than IgG1 or IgG3 antibodies in facilitating opsonization and eliminating infected cells.
SCIENCE IMMUNOLOGY
(2023)
Review
Endocrinology & Metabolism
Mausumi Das, Weon-Young Son
Summary: In vitro maturation (IVM) is a viable option for specific patients, including those at risk of ovarian hyperstimulation syndrome (OHSS), in need of urgent fertility preservation, or when controlled ovarian stimulation is not possible. The clinical applications of IVM are expanding rapidly and it is now classified as a non-experimental technique. IVM offers advantages over conventional IVF, such as reduced stimulation and risk of OHSS, shorter treatment times, and lower costs. However, challenges remain in terms of technical expertise and lower success rates compared to traditional IVF. Ongoing research aims to refine protocols and improve the efficiency and effectiveness of IVM.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Pediatrics
Anton Holmgren, Gabriel A. Martos-Moreno, Aimon Niklasson, Julian Martinez-Villanueva, Jesus Argente, Kerstin Albertsson-Wikland
Summary: The study found that in childhood obesity, a higher BMI is associated with lower pubertal height gain; for boys, a higher BMI is related to an earlier onset of pubertal growth; for girls, this correlation is not linear.
PEDIATRIC RESEARCH
(2021)
Article
Genetics & Heredity
Cecilia S. Blengini, Patricia Ibrahimian, Michaela Vaskovicova, David Drutovic, Petr Solc, Karen Schindler
Summary: The study demonstrates the essential role of AURKA in meiosis I of mouse oocytes, showing that it regulates multiple crucial steps such as activating key kinases and regulating protein localization, which distinguishes it from the other two homologs.
Article
Obstetrics & Gynecology
Gilad Karavani, Koral Vedder, Einat Gutman-Ido, Raizl Gruda Sussman, Neta Goldschmidt, Talya Mordechai-Daniel, Assaf Ben-Meir, Tal Imbar
Summary: Chemotherapy exposure does not affect the in vitro maturation (IVM) potential of immature oocytes retrieved from ovarian tissue cryopreservation (OTC), but rather depends on the patient's age. Successful retrieval of immature oocytes from ovarian tissue is negatively affected by chemotherapy and its timing.
HUMAN REPRODUCTION
(2023)
Article
Cell Biology
Gilad Karavani, Peera Wasserzug-Pash, Talya Mordechai-Daniel, Dvora Bauman, Michael Klutstein, Tal Imbar
Summary: The study evaluated in vitro maturation (IVM) outcomes in 133 chemotherapy naive patients aged 1-35 years. The results showed a gradual increase in IVM rates from 1 to 24 years, with a peak in the 18-24 years group and a decrease in the 25-35 years group. Significantly lower success rates were observed in patients under 6 years old and over 30 years old compared to the 18-24 years group.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Nina M. Alyoshina, Maria D. Tkachenko, Yulia O. Nikishina, Denis A. Nikishin
Summary: This study found that the activity of serotonin transporter (SERT) in oocytes is correlated with indicators of follicular selection and oocyte maturity. The accumulation of exogenous serotonin in maturing mammalian oocytes occurs due to SERT activity. Immunohistochemical study showed that the difference in 5-HT intake activity in oocytes does not correlate with apoptosis marker in follicular cells, but positively correlates with markers of follicular growth. Functional analysis showed that SERT expression and activity increase with oocyte maturation. Administration of fluoxetine, a selective serotonin reuptake inhibitor, significantly decreases serotonin content in growing and mature oocytes, indicating that membrane transport of serotonin is a promising marker of their mature status.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Pediatrics
Audrey-Anne Milette, Lindsay L. Richter, Claude Julie Bourque, Annie Janvier, Rebecca Pearce, Paige Terrien Church, Anne Synnes, Thuy Mai Luu
Summary: Parents of preterm children have positive views on the health and development of their children, regardless of neurodevelopmental impairment (NDI). Parents of children without NDI tend to appreciate their children's social interactions more, while parents of children with NDI are more likely to express concerns. Development, the child's future, and physical health are the most common areas of concern for parents.
Article
Biochemistry & Molecular Biology
Fan Chen, Xiao-Fei Jiao, Fei Meng, Yong-Sheng Wang, Zhi-Ming Ding, Yi-Liang Miao, Jia-Jun Xiong, Li-Jun Huo
Summary: Rae1 is a crucial regulator of mouse oocyte meiotic maturation, modulating the protein levels of Securin and impacting chromosome alignment, K-MT attachments, and aneuploidy during meiosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Economics
Anna Pauliina Sandqvist, Boriss Siliverstovs
Summary: The study reveals that unusual weather significantly impacts consumer spending at the macro-level, with particularly high or low temperatures causing sizeable intertemporal shifts in spending. The effects of abnormal weather differ across seasons, mainly manifesting through the seasons change channel.
EMPIRICAL ECONOMICS
(2021)
Article
Cell Biology
Yu-Jin Jo, Jeongwoo Kwon, Zhe-Long Jin, Suk Namgoong, Taeho Kwon, Seung-Bin Yoon, Dong-Ho Lee, Ji-Su Kim, Nam-Hyung Kim
Summary: WHAMM plays a crucial role in mammalian oocyte maturation by regulating spindle formation and chromosome alignment, ultimately impacting the symmetry of cell division.
Article
Endocrinology & Metabolism
Meng Wang, Qiyu Yang, Jing Liu, Juan Hu, Dan Li, Xinling Ren, Qingsong Xi, Lixia Zhu, Lei Jin
Summary: This study found that oocyte developmental parameters during in vitro maturation (IVM) can affect the clinical outcomes of intracytoplasmic sperm injection (ICSI) cycles. The rates of germinal vesicle breakdown (GVBD) and polar body 1 extrusion were recorded, and it was concluded that GVBD rate and progesterone level on human chorionic gonadotropin (HCG) day may be associated with pregnancy outcomes in infertile couples during ICSI.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Japan Huynh
Summary: This paper extends the existing literature by examining the impact of bank competition on the real economy through its influence on bank lending in terms of price, volume, and quality. The study finds that intense competition leads to a decline in bank loan growth and an increase in credit risk. The association between bank competition and credit prices varies depending on the measures used to analyze market structure. The findings also suggest that banks with higher income diversification are less affected by the adverse effects of competition on lending.
Article
Behavioral Sciences
Mengxue Lan, Maoying Peng, Xiaolin Zhao, Huixiang Li, Juan Yang
Summary: The study found that people are less willing to express stereotypes about ugliness, while it is easier for them to express positive views about beauty, which requires more mental resources.
Article
Obstetrics & Gynecology
Marcia C. Inhorn, Daphna Birenbaum-Carmeli, Pasquale Patrizio
Summary: Although the main reason for women to pursue elective egg freezing is often the lack of a male partner, nearly two-thirds of women in the study still relied on some form of male support during their decision-making processes and procedures. Male support came in various forms and provided assistance in different categories, indicating the 'hidden' roles men play in supporting women's reproductive aspirations.
Editorial Material
Genetics & Heredity
David F. Albertini
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2020)
Editorial Material
Genetics & Heredity
David F. Albertini
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2020)
Editorial Material
Genetics & Heredity
David F. Albertini
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2021)
Article
Agriculture, Dairy & Animal Science
Valentina Lodde, Alberto Maria Luciano, Giulia Musmeci, Ileana Miclea, Irene Tessaro, Mariella Aru, David F. Albertini, Federica Franciosi
Summary: Women's reproductive performance declines starting in midlife, with a very low possibility of pregnancy by age 40-45. Premature ovarian failure and early ovarian aging can lead to low-quality eggs, impacting fertility. Understanding cellular mechanisms is essential for finding solutions to reproductive aging issues.
Article
Genetics & Heredity
Pierre Comizzoli, Pasqualino Loi, Pasquale Patrizio, Allison Hubel
Summary: Long-term preservation of high-quality sperm, eggs, embryos, and gonadal tissues is crucial for human reproductive medicine and population management. Research suggests that suspending gametes or gonadal tissues in trehalose glass after dehydration and storing them at supra-zero temperatures can be an alternative to freezing.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Editorial Material
Genetics & Heredity
Pasquale Patrizio, David F. Albertini, Norbert Gleicher, Arthur Caplan
Summary: This analysis compares traditional non-profit academic institutions with new for-profit reproductive medicine practices, assessing the risks to patient care quality and the training of future reproductive medicine specialists with the entrance of investors into the for-profit reproductive medicine market.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Article
Agriculture, Dairy & Animal Science
Daniela Bebbere, Amir Arav, Stefano Mario Nieddu, Giovanni Pietro Burrai, Sara Succu, Pasquale Patrizio, Sergio Ledda
Summary: Freeze-drying is a method for preserving cells and tissues, offering cost savings and improved stability; sheep ovarian tissue survived the process, maintaining its structure and responding to specific genes.
Editorial Material
Medical Laboratory Technology
Pasquale Patrizio, Norbert Gleicher
CLINICAL CHEMISTRY
(2023)
Article
Obstetrics & Gynecology
D. H. Barad, D. F. Albertini, E. Molinari, N. Gleicher
Summary: This study aimed to investigate the effects of intraovarian injection of platelet-rich plasma (PRP) on ovarian function in patients with extremely low functional ovarian reserve (LFOR). The results showed that PRP treatment did not have clinically significant effects on ovarian function over a 1-year follow-up period. However, two patients with poor prognosis achieved pregnancy after PRP treatment. The study suggests that sporadic pregnancies are possible even in extremely poor prognosis patients due to LFOR, but further research is needed to determine the role of PRP treatments in these pregnancies.
HUMAN REPRODUCTION OPEN
(2022)
Article
Social Issues
Marcia C. Inhorn, Daphna Birenbaum-Carmeli, Ruoxi Yu, Pasquale Patrizio
Summary: Recent studies have shown that highly educated professional women in their late thirties to early forties are turning to egg freezing as a method of fertility preservation while waiting for a suitable male partner. For many women, egg freezing offers a new hope for future relationships, but it can also be viewed as a technology of despair following the breakdown of a relationship.
SCIENCE TECHNOLOGY & HUMAN VALUES
(2022)
Article
Anthropology
Daphna Birenbaum-Carmeli, Marcia C. Inhorn, Mira D. Vale, Pasquale Patrizio
Summary: Egg freezing is increasingly popular among Jewish women in Israel and the United States, as it addresses medical and marital uncertainties and preserves Jewish motherhood. It serves as a protective self-preservation technology within their pronatalist social environments.
MEDICAL ANTHROPOLOGY QUARTERLY
(2021)
Article
Endocrinology & Metabolism
Norbert Gleicher, Sarah Darmon, Emanuela Molinari, Lin Zhang, Jianjun Hu, David F. Albertini, David H. Barad
Summary: This study found that young women under the age of 41 with adrenal hypoandrogenism may actually suffer from secondary ovarian insufficiency (SOI) rather than primary ovarian insufficiency (POI). In some cases, this condition could be treated with androgen supplementation.
Article
Obstetrics & Gynecology
A. Weghofer, D. H. Barad, S. K. Darmon, V. A. Kushnir, D. F. Albertini, N. Gleicher
HUMAN REPRODUCTION OPEN
(2020)
Meeting Abstract
Obstetrics & Gynecology
David H. Barad, David F. Albertini, Norbert Gleicher
FERTILITY AND STERILITY
(2020)
