Review
Biotechnology & Applied Microbiology
Pramila Murugesan, Gokul Raj, J. A. Moses
Summary: Pesticides are harmful to human, animal, and environmental health due to their residues. Microfluidic devices are being increasingly recognized as effective tools for pesticide detection, thanks to their miniaturization, portability, and sensitivity. This review provides an overview of the latest advances in microfluidic devices for pesticide detection applications.
REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Chungen Qian, Yujin Xiao, Jie Wang, Yiwei Li, Shunji Li, Bo Wei, Wei Du, Xiaojun Feng, Peng Chen, Bi-Feng Liu
Summary: Exosomes, along with their associated proteins and nucleic acids, are recognized as biomarkers for tumor diagnosis and prognosis. Detecting exosomes is challenging due to their small size and low concentration. A low-cost, rapid, and portable agarose-based microfluidic chip for exosome concentration and in situ exosomal microRNA detection was developed, providing a new avenue for early cancer detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Agriculture, Multidisciplinary
Lingyuan Xu, A. M. Abd El-Aty, Jong-Bang Eun, Jae -Han Shim, Jing Zhao, Xingmei Lei, Song Gao, Yongxin She, Fen Jin, Jing Wang, Maojun Jin, Bruce D. Hammock
Summary: This review introduces the current trends and hotspots in on-site detection of pesticide residues in agricultural products. It provides a detailed overview of different technologies, their characteristics, research status, and applications. It also analyzes the challenges and future prospects for the development of pesticide residue detection.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Agriculture, Multidisciplinary
Lingyuan Xu, A. M. Abd El-Aty, Jong-Bang Eun, Jae -Han Shim, Jing Zhao, Xingmei Lei, Song Gao, Yongxin She, Fen Jin, Jing Wang, Maojun Jin, Bruce D. Hammock
Summary: This review introduces the currently available technologies for the rapid detection of pesticide residues, including electrochemistry, optical analysis, biotechnology, and other innovative approaches. It also analyzes the challenges and future development prospects.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Biochemical Research Methods
Lv Zhu, Mengyao Wu, Ruiyu Li, Yunyan Zhao, Yang Lu, Ting Wang, Leilei Du, Li Wan
Summary: The problem of pesticide residue contamination is a concern for human health. Traditional pesticide residue detection methods are not capable of meeting the requirements for rapid and diverse field screening. Microfluidic technology, which integrates sample preparation and detection, shows great potential for quick and accurate high-throughput detection of pesticide residues. This paper reviews the latest research progress, including commonly used microfluidic materials, current detection technology, and future research directions.
Review
Chemistry, Physical
Robert Bogdanowicz, Martin Jonsson-Niedziolka, Elizaveta Vereshchagina, Anna Dettlaff, Suchanat Boonkaew, Mattia Pierpaoli, Paul Wittendorp, Shruti Jain, Frode Tyholdt, Jacob Thomas, Pawel Wojcik
Summary: This review discusses recent advancements in electrochemical devices used for photo- and spectroelectrochemical investigations. It focuses on the miniaturization of devices, such as nanointerdigitated complementary metal-oxide-semiconductor devices, micro- and nano-porous silicon membranes, and microoptoelectromechanical spectroscopy or optical microcavities. Polymer-based devices are also evaluated for their efficiency in various applications, including bioelectrochemical systems, biocatalysis, photochemical synthesis, and single nanoparticle spectroelectrochemistry. The review also discusses the challenges and future prospects of microfluidic and spectroelectrochemical devices.
CURRENT OPINION IN ELECTROCHEMISTRY
(2022)
Article
Chemistry, Analytical
Guoying Hao, Hongye Tian, Zhong Zhang, Xiaoxiao Qin, Tian Yang, Li Yuan, Xingbin Yang
Summary: By using L-cysteine modified carbon quantum dots (CQDs) and CdTe quantum dots (CdTe QDs) as fluorescence signals, a novel dual-channel and dual-signal microfluidic paper chip was developed for portable and rapid analysis of difenoconazole and mancozeb. The chip achieved simultaneous detection of the two pesticides in a mixed solution with great stability and fluorescence property. This work provides a useful exploration for the development of new universal rapid detection technologies and theories and has great significance for the rapid detection of pesticide residues in export products.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Haiqing Bai, Kristen N. Peters Olson, Ming Pan, Thomas Marshall, Hardeep Singh, Jingzhe Ma, Paige Gilbride, Yu-Chieh Yuan, Jenna McCormack, Longlong Si, Sushila Maharjan, Di Huang, Xiaohua Qian, Carol Livermore, Yu Shrike Zhang, Xin Xie
Summary: This study introduces an approach to pattern fluid guides inside microchannels by establishing differential hydrophilicity using pressure-sensitive adhesives as masks and a subsequent selective coating with a biocompatible polymer. The method achieves rapid and consistent hydrogel flow and is suitable for dynamic 3D cell culture. Additionally, the device shows potential for pharmaceutical high-throughput screening applications.
Article
Chemistry, Analytical
Jiaqing Xie, Haoran Pang, Ruqian Sun, Tao Wang, Xiaoyu Meng, Zhikang Zhou
Summary: This study proposed a colorimetric device based on a microfluidic mixer chip for rapid and high-precision detection of organophosphorus pesticide residues, with a minimum detection concentration of 0.045 mg/L and an average detection time of 60 seconds. The results provide a theoretical and experimental basis for portable and high-precision detection of pesticide residues.
Article
Microbiology
Weiwei Jiang, Dongying Hu, Yanyan Xu, Yang Chen, Xiaoyang Zhu, Zhao Han, Xin Ye, Xiaojing Li
Summary: In this study, LAMP primers for Trichophyton were designed and a LAMP-Microfluidic chip detection system was developed. The system exhibited high specificity and sensitivity, enabling the detection of six common species of Trichophyton without cross-reactivity with other dermatophytes. The system has the potential for clinical application, offering a simple and efficient way to detect Trichophyton infections.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Engineering, Electrical & Electronic
Goran M. Stojanovic, Tijana Kojic, Mitar Simic, Aleksandra Jovanovic-Galovic, Bojan Pavlovic, Amaia Zurutuza, Luca Anzi, Roman Sordan
Summary: A compact microfluidic platform for selective detection of ascorbic acid was presented in this paper, with the application of graphene improving response linearity and reducing detection and quantification limits compared to the reference structure.
IEEE SENSORS JOURNAL
(2021)
Review
Biotechnology & Applied Microbiology
Tong Wu, Yangyang Wu, Jinfeng Yan, Jinjin Zhang, Shixuan Wang
Summary: Assisted reproductive technology aims to select high-quality reproductive cells and embryos for successful pregnancy. Microfluidic chips provide a powerful tool for functional evaluation, offering reduced size, precise control, and flexible extension.
BIOENGINEERING & TRANSLATIONAL MEDICINE
(2023)
Article
Chemistry, Analytical
Roberto Paoli, Davide Di Giuseppe, Maider Badiola-Mateos, Eugenio Martinelli, Maria Jose Lopez-Martinez, Josep Samitier
Summary: This paper discusses the application of digital manufacturing and rapid prototyping technologies in Organ-on-a-Chip applications, as well as the main thermoplastic material choices and manufacturing methods, and investigates the limitations of the PDMS soft lithography strategy.
Article
Food Science & Technology
Wentao Su, Duo Liang, Mingqian Tan
Summary: Microfluidic technology provides a new way for rapid and effective detection of food allergens, with the advantages of low sample/reagent consumption and integrated detection, making it suitable for on-site use and more convenient for consumers.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Review
Chemistry, Analytical
Inae Lee, Eunyoung Jeon, Joonseok Lee
Summary: As the importance of monitoring bioaerosols for the control and prevention of airborne epidemic diseases outbreaks is increasing, microfluidic devices have shown potential for on-site bio-aerosol monitoring. This review discusses the measurement of airborne microorganisms, sampling strategies, and analytical methodologies. Recent advancements in microfluidic platforms include sample preparation strategies and rapid detection methods on microfluidic chips.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)