Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: The complex triangle of brain amyloidosis

Vascular dysfunction—The disregarded partner of Alzheimer's disease

(2019) Melanie D. Sweeney et al.   Alzheimers & Dementia

Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease

(2018) David M. A. Mann et al.   ACTA NEUROPATHOLOGICA

Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP

(2018) Frances K Wiseman et al.   BRAIN

Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation

(2018) Patrick J. Lao et al.   Brain Imaging and Behavior

Clinical aspects and biomarkers of Alzheimer's disease in Down syndrome

(2018) Panagiotis Zis et al.   FREE RADICAL BIOLOGY AND MEDICINE

Core cerebrospinal fluid biomarker profile in cerebral amyloid angiopathy

(2018) Andreas Charidimou et al.   NEUROLOGY

The pathology and pathophysiology of vascular dementia

(2018) Raj N. Kalaria   NEUROPHARMACOLOGY

Neuroimaging and other modalities to assess Alzheimer's disease in Down syndrome

(2018) Natalie Neale et al.   NeuroImage-Clinical

The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer’s disease in individuals with Down syndrome

(2018) Yvonne S. Davidson et al.   Acta Neuropathologica Communications

Increased cerebral microbleeds and cortical superficial siderosis in pediatric patients with Down syndrome

(2018) Franziska Schoeppe et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Plasma Amyloid-β as a Function of Age, Level of Intellectual Disability, and Presence of Dementia in Down Syndrome

(2018) Elizabeth Head et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-Related Imaging Abnormalities in AβPP Duplication Carriers

(2018) Ludivine Chamard et al.   JOURNAL OF ALZHEIMERS DISEASE

Relationship Between β-Secretase, Inflammation and Core Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

(2018) Daniel Alcolea et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

(2018) Juan Fortea et al.   LANCET NEUROLOGY

Cerebral Cortical Microinfarcts on Magnetic Resonance Imaging and Their Association With Cognition in Cerebral Amyloid Angiopathy

(2018) Li Xiong et al.   STROKE

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease

(2018) Iris J. Broce et al.   ACTA NEUROPATHOLOGICA

Racial and ethnic estimates of Alzheimer's disease and related dementias in the United States (2015–2060) in adults aged ≥65 years

(2018) Kevin A. Matthews et al.   Alzheimers & Dementia

Cerebrovascular disorders associated with genetic lesions

(2018) Philipp Karschnia et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microbleeds and Cerebral Amyloid Angiopathy in the Brains of People with Down Syndrome with Alzheimer’s Disease

(2018) Alex M. Helman et al.   JOURNAL OF ALZHEIMERS DISEASE

Prevalence of Sleep Disorders in Adults With Down Syndrome: A Comparative Study of Self-Reported, Actigraphic, and Polysomnographic Findings

(2018) Sandra Giménez et al.   Journal of Clinical Sleep Medicine

Intracerebral haemorrhage: current approaches to acute management

(2018) Charlotte Cordonnier et al.   LANCET

Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years

(2018) Rosalyn Hithersay et al.   JAMA Neurology

Anomalous White Matter Structure and the Effect of Age in Down Syndrome Patients

(2017) Raquel Fenoll et al.   JOURNAL OF ALZHEIMERS DISEASE

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The Role of APP

(2017) Eric Doran et al.   JOURNAL OF ALZHEIMERS DISEASE

The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis

(2017) Tiina Annus et al.   NEUROBIOLOGY OF AGING

Distribution of lacunes in cerebral amyloid angiopathy and hypertensive small vessel disease

(2017) Marco Pasi et al.   NEUROLOGY

Cerebrovascular pathology in Down syndrome and Alzheimer disease

(2017) Elizabeth Head et al.   Acta Neuropathologica Communications

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

(2016) Raj N. Kalaria   ACTA NEUROPATHOLOGICA

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

(2016) M. Florencia Iulita et al.   Alzheimers & Dementia

Cerebrovascular contributions to aging and Alzheimer's disease in Down syndrome

(2016) Donna M. Wilcock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Estimation of the number of people with Down syndrome in the United States

(2016) Gert de Graaf et al.   GENETICS IN MEDICINE

Feasibility of Lumbar Puncture in the Study of Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease in Subjects with Down Syndrome

(2016) María Carmona-Iragui et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database

(2016) John M. Ringman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study

(2016) Panagiotis Fotiadis et al.   LANCET NEUROLOGY

Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study

(2016) Zoe Arvanitakis et al.   LANCET NEUROLOGY

Dementia in Down's syndrome

(2016) Clive Ballard et al.   LANCET NEUROLOGY

Cerebral β-Amyloid Angiopathy Is Associated with Earlier Dementia Onset in Alzheimer's Disease

(2016) Eric D. Vidoni et al.   Neurodegenerative Diseases

β-Amyloid in CSF

(2016) Ellis S. van Etten et al.   NEUROLOGY

Recurrent hemorrhage risk and mortality in hereditary and sporadic cerebral amyloid angiopathy

(2016) Ellis S. van Etten et al.   NEUROLOGY

Cortical superficial siderosis

(2016) Sara Shams et al.   NEUROLOGY

Sporadic Cerebral Amyloid Angiopathy: Pathophysiology, Neuroimaging Features, and Clinical Implications

(2016) Gregoire Boulouis et al.   SEMINARS IN NEUROLOGY

Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage

(2015) Sergi Martinez-Ramirez et al.   Alzheimers & Dementia

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

(2015) Heather M. Snyder et al.   Alzheimers & Dementia

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

(2015) Andreas Charidimou et al.   BRAIN

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

(2015) Elizabeth Head et al.   Current Alzheimer Research

Clinical profile and main comorbidities of Spanish adults with Down syndrome

(2015) Diego Real de Asua et al.   European Journal of Internal Medicine

Cerebral Amyloid Angiopathy-Related Atraumatic Convexal Subarachnoid Hemorrhage: An ARIA before the Tsunami

(2015) Eva Martínez-Lizana et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Correlates of sedentary behaviour in youths with Down syndrome: the UP&DOWN study

(2015) Rocío Izquierdo-Gomez et al.   JOURNAL OF SPORTS SCIENCES

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

(2015) Frances K. Wiseman et al.   NATURE REVIEWS NEUROSCIENCE

Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes

(2015) Willa D. Brenowitz et al.   NEUROBIOLOGY OF AGING

Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease

(2015) Natalie S. Ryan et al.   NEUROBIOLOGY OF AGING

APOE and cerebral amyloid angiopathy in community-dwelling older persons

(2015) Lei Yu et al.   NEUROBIOLOGY OF AGING

Cerebral amyloid angiopathy with and without hemorrhage: Evidence for different disease phenotypes

(2015) A. Charidimou et al.   NEUROLOGY

Risk of Major Cardiovascular Events in People with Down Syndrome

(2015) Christopher G. Sobey et al.   PLoS One

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy

(2014) Y. D. Reijmer et al.   BRAIN

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Outcome markers for clinical trials in cerebral amyloid angiopathy

(2014) Steven M Greenberg et al.   LANCET NEUROLOGY

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

(2014) Alberto Lleó et al.   Nature Reviews Neurology

Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: Implications for amyloid-modifying therapies

(2013) Fabrizio Piazza et al.   ANNALS OF NEUROLOGY

People with intellectual disability: What do we know about adulthood and life expectancy?

(2013) A.M.W. Coppus   Developmental Disabilities Research Reviews

Transient Focal Neurological Episodes, Cerebral Amyloid Angiopathy, and Intracerebral Hemorrhage Risk: Looking beyond TIAs

(2013) Andreas Charidimou et al.   International Journal of Stroke

Genetics of cerebral amyloid angiopathy: systematic review and meta-analysis

(2013) K. Rannikmae et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Cortical superficial siderosis and intracerebral hemorrhage risk in cerebral amyloid angiopathy

(2013) A. Charidimou et al.   NEUROLOGY

Topography of dilated perivascular spaces in subjects from a memory clinic cohort

(2013) S. Martinez-Ramirez et al.   NEUROLOGY

Low heart-type fatty acid binding protein level during aging may protect down syndrome people against atherosclerosis

(2013) Elena Vianello et al.   Immunity & Ageing

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

(2012) Marta Pera et al.   ACTA NEUROPATHOLOGICA

The paradox of syndromic diversity in Alzheimer disease

(2012) Jason D. Warren et al.   Nature Reviews Neurology

Sedentary behavior: Understanding and influencing adults' prolonged sitting time

(2012) Neville Owen   PREVENTIVE MEDICINE

Spectrum of Transient Focal Neurological Episodes in Cerebral Amyloid Angiopathy

(2012) Andreas Charidimou et al.   STROKE

Microinfarcts, brain atrophy, and cognitive function: The Honolulu Asia Aging Study Autopsy Study

(2011) Lenore J. Launer et al.   ANNALS OF NEUROLOGY

Cerebral amyloid angiopathy in the elderly

(2011) Anand Viswanathan et al.   ANNALS OF NEUROLOGY

Positron Emission Tomography and Neuropathologic Estimates of Fibrillar Amyloid-β in a Patient With Down Syndrome and Alzheimer Disease

(2011) Marwan N. Sabbagh   ARCHIVES OF NEUROLOGY

Acute ischaemic brain lesions in intracerebral haemorrhage: multicentre cross-sectional magnetic resonance imaging study

(2011) Simone M. Gregoire et al.   BRAIN

MMP-2/MMP-9 Plasma Level and Brain Expression in Cerebral Amyloid Angiopathy-Associated Hemorrhagic Stroke

(2011) Mar Hernandez-Guillamon et al.   BRAIN PATHOLOGY

Cerebral Amyloid Angiopathy: A Systematic Review

(2011) Alessandro Biffi et al.   Journal of Clinical Neurology

Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum

(2011) Andreas Charidimou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome

(2011) Antonia M.W. Coppus et al.   NEUROBIOLOGY OF AGING

Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implications

(2011) Deborah A. Levine et al.   Neurotherapeutics

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

(2011) Randall J Bateman et al.   Alzheimers Research & Therapy

Comparison of Intima-Media Thickness of the Carotid Artery and Cardiovascular Disease Risk Factors in Adults With Versus Without the Down Syndrome

(2010) Christopher C. Draheim et al.   AMERICAN JOURNAL OF CARDIOLOGY

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

(2010) Zoe Arvanitakis et al.   ANNALS OF NEUROLOGY

Variants at APOE influence risk of deep and lobar intracerebral hemorrhage

(2010) Alessandro Biffi et al.   ANNALS OF NEUROLOGY

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy

(2010) J. Linn et al.   NEUROLOGY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Alzheimer’s disease beyond APOE

(2009) Michael A van Es et al.   NATURE GENETICS

Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease

(2008) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

The impact of apolipoprotein E on dementia in persons with Down's syndrome

(2007) A.M.W. Coppus et al.   NEUROBIOLOGY OF AGING