Histone methyltransferase G9a protects against acute liver injury through GSTP1

Liver-specific knockout of histone methyltransferase G9a impairs liver maturation and dysregulates inflammatory, cytoprotective, and drug-processing genes

(2018) Hong Lu et al.   XENOBIOTICA

Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure

(2017) Benjamin L. Woolbright et al.   JOURNAL OF HEPATOLOGY

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

(2017) Ryan Rickels et al.   NATURE GENETICS

MacroH2A1.1 cooperates with EZH2 to promote adipogenesis by regulating Wnt signaling

(2017) Danyang Wan et al.   Journal of Molecular Cell Biology

Regulation of cell differentiation and function by the euchromatin histone methyltranserfases G9a and GLP

(2016) Jamie M. Kramer   Biochemistry and Cell Biology

Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression

(2016) Taisuke Irifuku et al.   KIDNEY INTERNATIONAL

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression

(2016) Xi Zhang et al.   Nature Communications

Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides

(2015) D. Bartolini et al.   FREE RADICAL BIOLOGY AND MEDICINE

NRF2/KEAP1 and Wnt/β-catenin in the multistep process of liver carcinogenesis in humans and rats

(2015) Jean-Charles Nault et al.   HEPATOLOGY

Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses

(2015) Yang Liu et al.   JOURNAL OF HEPATOLOGY

Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice

(2015) Daniel J. Conklin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

(2015) J Pajaud et al.   Cell Death & Disease

Single-Dose GSTP1 Prevents Infarction-Induced Heart Failure

(2014) Olena Andrukhova et al.   JOURNAL OF CARDIAC FAILURE

Identification by high-throughput imaging of the histone methyltransferase EHMT2 as an epigenetic regulator of VEGFA alternative splicing

(2014) Maayan Salton et al.   NUCLEIC ACIDS RESEARCH

Random monoallelic expression: regulating gene expression one allele at a time

(2014) Mélanie A. Eckersley-Maslin et al.   TRENDS IN GENETICS

The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation

(2013) Jane Ding et al.   Cell Metabolism

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

(2012) Terry C. Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased Skin Papilloma Formation in Mice Lacking Glutathione Transferase GSTP

(2011) C. J. Henderson et al.   CANCER RESEARCH

Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice

(2011) Tung Ming Leung et al.   HEPATOLOGY

Increased Sensitivity of Glutathione S-Transferase P-Null Mice to Cyclophosphamide-Induced Urinary Bladder Toxicity

(2009) D. J. Conklin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

(2008) Makoto Tachibana et al.   EMBO JOURNAL

G9a and HP1 Couple Histone and DNA Methylation to TNFα Transcription Silencing during Endotoxin Tolerance

(2008) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombinant protein glutathione S-transferases P1 attenuates inflammation in mice

(2008) Lan Luo et al.   MOLECULAR IMMUNOLOGY