Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Published 2019 View Full Article

Authors

Keywords

in vivo CRISPR screen, CD8 T cell, tumor infiltration, DHX37, immunotherapy, target discovery, adoptive transfer, breast cancer, T cell effector function, lentiCRISPR

Journal

CELL

Volume 178, Issue 5, Pages 1189-1204.e23

Publisher

Elsevier BV

Online

2019-08-22

DOI

10.1016/j.cell.2019.07.044

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