A VEGFR2–MICA bispecific antibody activates tumor-infiltrating lymphocytes and exhibits potent anti-tumor efficacy in mice
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A VEGFR2–MICA bispecific antibody activates tumor-infiltrating lymphocytes and exhibits potent anti-tumor efficacy in mice
Authors
Keywords
Cancer immunotherapy, Bispecific antibody, Tumor-infiltrating lymphocyte, VEGFR2
Journal
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume 68, Issue 9, Pages 1429-1441
Publisher
Springer Science and Business Media LLC
Online
2019-08-20
DOI
10.1007/s00262-019-02379-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Prognostic value of serum levels of soluble MICA (sMICA) in patients with prostate cancer
- (2018) Y Liu et al. BRITISH JOURNAL OF BIOMEDICAL SCIENCE
- Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa
- (2018) Kabir A. Khan et al. Nature Reviews Clinical Oncology
- Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity
- (2018) Lucas Ferrari de Andrade et al. SCIENCE
- Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
- (2017) Keehoon Jung et al. JOURNAL OF CLINICAL INVESTIGATION
- A Novel Fusion Antibody Exhibits Antiangiogenic Activity and Stimulates NK Cell-mediated Immune Surveillance Through Fused NKG2D Ligand
- (2017) Desmond O. Acheampong et al. JOURNAL OF IMMUNOTHERAPY
- A bispecific protein rG7S-MICA recruits natural killer cells and enhances NKG2D-mediated immunosurveillance against hepatocellular carcinoma
- (2016) Tong Wang et al. CANCER LETTERS
- Antiangiogenic therapy in oncology: current status and future directions
- (2016) Gordon C Jayson et al. LANCET
- Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
- (2016) Jeffrey J. Wallin et al. Nature Communications
- Regulation of NKG2D+CD8+ T-cell-mediated antitumor immune surveillance: Identification of a novel CD28 activation-mediated, STAT3 phosphorylation-dependent mechanism
- (2016) Jiemiao Hu et al. OncoImmunology
- Intratumoral Myeloid Cells Regulate Responsiveness and Resistance to Antiangiogenic Therapy
- (2015) Lee B. Rivera et al. Cell Reports
- High Expression of MICA in Human Kidney Cancer Tissue and Renal Cell Carcinoma Lines
- (2014) Hong-Ying Jia et al. Asian Pacific Journal of Cancer Prevention
- Generation and characterization of a novel human IgG1 antibody against vascular endothelial growth factor receptor 2
- (2014) Wei Xie et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Cutting Edge: The Metalloproteinase ADAM17/TNF- -Converting Enzyme Regulates Proteolytic Shedding of the MHC Class I-Related Chain B Protein
- (2014) P. Boutet et al. JOURNAL OF IMMUNOLOGY
- IFNγ-responsiveness of endothelial cells leads to efficient angiostasis in tumours involving down-regulation of Dll4
- (2014) Jingjing Deng et al. JOURNAL OF PATHOLOGY
- Bevacizumab plus Ipilimumab in Patients with Metastatic Melanoma
- (2014) F. S. Hodi et al. Cancer Immunology Research
- Regulation of Ligands for the NKG2D Activating Receptor
- (2013) David H. Raulet et al. Annual Review of Immunology
- Phage-derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF
- (2012) Juan Zhang et al. BIOTECHNOLOGY PROGRESS
- Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding
- (2012) Leticia Huergo-Zapico et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Anti-VEGF/VEGFR Therapy for Cancer: Reassessing the Target
- (2012) B. Sitohy et al. CANCER RESEARCH
- Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
- (2012) Y. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor angiogenesis: molecular pathways and therapeutic targets
- (2011) Sara M Weis et al. NATURE MEDICINE
- Antiangiogenic Agents Can Increase Lymphocyte Infiltration into Tumor and Enhance the Effectiveness of Adoptive Immunotherapy of Cancer
- (2010) R. K. Shrimali et al. CANCER RESEARCH
- NK cell-mediated killing of target cells triggers robust antigen-specific T cell-mediated and humoral responses
- (2009) P. Krebs et al. BLOOD
- Responsiveness of Stromal Fibroblasts to IFN- Blocks Tumor Growth via Angiostasis
- (2009) Y. Lu et al. JOURNAL OF IMMUNOLOGY
- Tumor-Associated MICA Is Shed by ADAM Proteases
- (2008) I. Waldhauer et al. CANCER RESEARCH
- MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
- (2008) M. Jinushi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started