Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse

Title
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse
Authors
Keywords
medulloblastomas, sonic hedgehog (SHH) signaling, single-cell transcriptomics, progenitor heterogeneity, glial progenitors, OPC-like, OLIG2, recurrent tumors, HIPPO-YAP/TAZ, AURORA-A/MYCN
Journal
CANCER CELL
Volume 36, Issue 3, Pages 302-318.e7
Publisher
Elsevier BV
Online
2019-08-29
DOI
10.1016/j.ccell.2019.07.009

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