How I manage severe von Willebrand disease

Platelets compensate for poor thrombin generation in type 3 von Willebrand disease

(2019) Timea Szanto et al.   PLATELETS

Evolution of replacement therapy for von Willebrand dicsease: From plasma fraction to recombinant von Willebrand factor

(2019) Flora Peyvandi et al.   BLOOD REVIEWS

Pregnancy and delivery in women with von Willebrand disease

(2019) Giancarlo Castaman et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Von Willebrand disease and gastrointestinal bleeding: A national inpatient sample study

(2019) Anastasia Tsagianni et al.   THROMBOSIS RESEARCH

How I treat type 2B von Willebrand disease

(2018) Rebecca Kruse-Jarres et al.   BLOOD

Setting the stage for individualized therapy in hemophilia: What role can pharmacokinetics play?

(2018) H.C.A.M. Hazendonk et al.   BLOOD REVIEWS

Lenalidomide as a novel therapy for gastrointestinal angiodysplasia in von Willebrand disease

(2018) N. V. Khatri et al.   HAEMOPHILIA

Replacement therapy during surgery in von Willebrand disease needs personalization

(2018) E. Berntorp   HAEMOPHILIA

Analysis of current perioperative management with Haemate® P/Humate P® in von Willebrand disease: Identifying the need for personalized treatment

(2018) H. C. A. M. Hazendonk et al.   HAEMOPHILIA

High and long-term von Willebrand factor expression after Sleeping Beauty transposon-mediated gene therapy in a mouse model of severe von Willebrand disease

(2018) I. Portier et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Update on clinical gene therapy for hemophilia

(2018) George Q. Perrin et al.   BLOOD

Sports participation and physical activity in patients with von Willebrand disease

(2018) Ferdows Atiq et al.   HAEMOPHILIA

Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery

(2018) F. Peyvandi et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clinically relevant differences between assays for von Willebrand factor activity

(2018) J. Boender et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Long-Term Outcome after Joint Bleeds in Von Willebrand Disease Compared to Haemophilia A: A Post Hoc Analysis

(2018) Merel Timmer et al.   THROMBOSIS AND HAEMOSTASIS

Long-term impact of joint bleeds in von Willebrand disease: a nested case-control study

(2017) Karin P.M. van Galen et al.   HAEMATOLOGICA

Predictors of quality of life among adolescents and young adults with a bleeding disorder

(2017) John M. McLaughlin et al.   Health and Quality of Life Outcomes

Von Willebrand’s Disease

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Alloantibodies in von Willebrand Disease

(2017) Massimo Franchini et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Feasibility of the Von Willebrand disease PREVENT trial

(2017) Margaret V. Ragni et al.   THROMBOSIS RESEARCH

Von Willebrand disease mutation spectrum and associated mutation mechanisms

(2017) Annika de Jong et al.   THROMBOSIS RESEARCH

Long-term impact of joint bleeds in von Willebrand disease: a nested case-control study

(2017) Karin P.M. van Galen et al.   HAEMATOLOGICA

Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States

(2016) V. H. Flood et al.   BLOOD

Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A

(2016) S. W. Pipe et al.   BLOOD

Obstetric bleeding among women with inherited bleeding disorders: a retrospective study

(2016) L. Hawke et al.   HAEMOPHILIA

A prospective study of von Willebrand factor levels and bleeding in pregnant women with type 1 von Willebrand disease

(2016) S. L. Sood et al.   HAEMOPHILIA

Developments in the diagnostic procedures for von Willebrand disease

(2016) A. De Jong et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Von Willebrand’s Disease

(2016) Frank W.G. Leebeek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prophylaxis in von Willebrand Disease: Coming of Age?

(2016) Giorgia Saccullo et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Gastrointestinal bleeding from vascular malformations: Is octreotide effective to rescue difficult-to-treat patients?

(2016) Andrea Iannone et al.   Clinics and Research in Hepatology and Gastroenterology

von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease

(2015) Y. V. Sanders et al.   BLOOD

Diagnostic approach to von Willebrand disease

(2015) C. Ng et al.   BLOOD

Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease

(2015) J. C. Gill et al.   BLOOD

Changes in bleeding patterns in von Willebrand disease after institution of long-term replacement therapy

(2015) Elena Holm et al.   BLOOD COAGULATION & FIBRINOLYSIS

First report of inhibitory von Willebrand factor alloantibodies in type 2B von Willebrand disease

(2015) Marije Baaij et al.   BRITISH JOURNAL OF HAEMATOLOGY

Thalidomide for treatment of gastrointestinal bleedings due to angiodysplasia: a case report in acquired von Willebrand syndrome and review of the literature

(2015) E. T. Engelen et al.   HAEMOPHILIA

Joint bleeds in von Willebrand disease patients have significant impact on quality of life and joint integrity: a cross-sectional study

(2015) K. P. M. van Galen et al.   HAEMOPHILIA

Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey

(2015) S. C. M. Stoof et al.   HAEMOPHILIA

Prophylaxis escalation in severe von Willebrand disease: a prospective study from the von Willebrand Disease Prophylaxis Network

(2015) T. Abshire et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet-dependent von Willebrand factor activity. Nomenclature and methodology: communication from the SSC of the ISTH

(2015) I. Bodó et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The bleeding score predicts clinical outcomes and replacement therapy in adults with von Willebrand disease

(2014) A. B. Federici et al.   BLOOD

Desmopressin in treatment of haematological disorders and in prevention of surgical bleeding

(2014) Peter J. Svensson et al.   BLOOD REVIEWS

The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

(2014) Mike A. Laffan et al.   BRITISH JOURNAL OF HAEMATOLOGY

The natural history of occult or angiodysplastic gastrointestinal bleeding in von Willebrand disease

(2014) M. Makris et al.   HAEMOPHILIA

Postpartum von Willebrand factor levels in women with and without von Willebrand disease and implications for prophylaxis

(2014) A. H. James et al.   HAEMOPHILIA

Alloantibodies in von Willebrand disease

(2013) P. D. James et al.   BLOOD

Principles of care for the diagnosis and treatment of von Willebrand disease

(2013) G. Castaman et al.   HAEMATOLOGICA

Thrombotic adverse events to coagulation factor concentrates for treatment of patients with haemophilia and von Willebrand disease: a systematic review of prospective studies

(2012) A. COPPOLA et al.   HAEMOPHILIA

In Vivo Gene Transfer Strategies to Achieve Partial Correction of von Willebrand Disease

(2012) Lan Wang et al.   HUMAN GENE THERAPY

The evolution and value of bleeding assessment tools

(2012) NATALIA RYDZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Different bleeding risk in type 2A and 2M von Willebrand disease: a 2-year prospective study in 107 patients

(2012) G. CASTAMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Management of delivery with FVIII/VWF concentrates in a pregnant woman with type 3 von Willebrand disease and alloantibodies

(2012) Víctor Jiménez-Yuste et al.   THROMBOSIS AND HAEMOSTASIS

Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease

(2012) Eva M. de Wee et al.   THROMBOSIS AND HAEMOSTASIS

Gynaecological and obstetric bleeding in moderate and severe von Willebrand disease

(2011) Eva de Wee et al.   THROMBOSIS AND HAEMOSTASIS

Health-related quality of life among adult patients with moderate and severe von Willebrand disease

(2010) E. M. DE WEE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Impact of von Willebrand disease on health-related quality of life in a pediatric population

(2010) E. M. DE WEE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Anaphylaxis in patients with congenital bleeding disorders and inhibitors

(2009) Massimo Franchini et al.   BLOOD COAGULATION & FIBRINOLYSIS

Von Willebrand disease, angiodysplasia and atorvastatin

(2009) Raza Alikhan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease

(2009) A. D. METJIAN et al.   HAEMOPHILIA

Genetic testing for von Willebrand disease: the case for

(2009) I. R. PEAKE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Restoration of Plasma von Willebrand Factor Deficiency Is Sufficient to Correct Thrombus Formation After Gene Therapy for Severe von Willebrand Disease

(2008) Simon F. De Meyer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD

(2008) G. Castaman et al.   BLOOD

Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients

(2008) A. B. Federici et al.   BLOOD

Von Willebrand disease and angiodysplasia responding to atorvastatin

(2008) Mamta Sohal et al.   BRITISH JOURNAL OF HAEMATOLOGY

Bleeding scores in inherited bleeding disorders: clinical or research tools?

(2008) A. TOSETTO et al.   HAEMOPHILIA

von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA)

(2008) W. L. NICHOLS et al.   HAEMOPHILIA