Combined available nitrogen resources enhanced erythromycin production and preliminary exploration of metabolic flux analysis under nitrogen perturbations

Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea

(2016) Chongchong Chen et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea

(2016) Katarina Karničar et al.   Microbial Cell Factories

Optimization of the n-propanol concentration and feedback control strategy with electronic nose in erythromycin fermentation processes

(2016) Hong-Tu Zhao et al.   PROCESS BIOCHEMISTRY

Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis

(2015) Jana Kumpfmüller et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement

(2015) Qian Guo et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

GlnR-mediated regulation of nitrogen metabolism in the actinomycete Saccharopolyspora erythraea

(2014) Li-Li Yao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m3 fermenter

(2014) Yong Chen et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis

(2013) Yong Chen et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate

(2013) Yong Chen et al.   BIORESOURCE TECHNOLOGY

Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains

(2013) Yuan-Yuan Li et al.   BMC GENOMICS

Strain improvement and optimization studies for enhanced production of erythromycin in bagasse based medium using Saccharopolyspora erythraea MTCC 1103

(2013) C. Subathra Devi et al.   3 Biotech

Enhanced production of GDP-l-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli

(2011) Won-Heong Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253

(2011) Won Seok Jung et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhancement of xylitol production in Candida tropicalis by co-expression of two genes involved in pentose phosphate pathway

(2011) Irshad Ahmad et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Fermentation optimization and industrialization of recombinant Saccharopolyspora erythraea strains for improved erythromycin a production

(2011) Xiang Zou et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Nitrogen Source Optimization for Cellulase Production by Penicillium funiculosum, using a Sequential Experimental Design Methodology and the Desirability Function

(2009) Roberto Nobuyuki Maeda et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Enhancement of erythromycin A production with feeding available nitrogen sources in erythromycin biosynthesis phase

(2009) Xiang Zou et al.   BIORESOURCE TECHNOLOGY

Genetic Modulation of the Overexpression of Tailoring Genes eryK and eryG Leading to the Improvement of Erythromycin A Purity and Production in Saccharopolyspora erythraea Fermentation

(2008) Y. Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50L to 372m3 scale

(2008) Xiang Zou et al.   BIORESOURCE TECHNOLOGY

Application of oxygen uptake rate and response surface methodology for erythromycin production by Saccharopolyspora erythraea

(2008) Xiang Zou et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Improvement of erythromycin production by Saccharopolyspora erythraea in molasses based medium through cultivation medium optimization

(2007) H.A. El-Enshasy et al.   BIORESOURCE TECHNOLOGY