Disruption of the Molecular Circadian Clock and Cancer: An Epigenetic Link

The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy

(2018) Youqiong Ye et al.   Cell Systems

Circadian disruption and biomarkers of tumor progression in breast cancer patients awaiting surgery

(2015) E. Cash et al.   BRAIN BEHAVIOR AND IMMUNITY

Histone methylation modifiers in cellular signaling pathways

(2015) Hunain Alam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

FDA Approval: Belinostat for the Treatment of Patients with Relapsed or Refractory Peripheral T-cell Lymphoma

(2015) H.-Z. Lee et al.   CLINICAL CANCER RESEARCH

Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice

(2015) Kirsten C.G. Van Dycke et al.   CURRENT BIOLOGY

Circadian gene hClock enhances proliferation and inhibits apoptosis of human colorectal carcinoma cells in vitro and in vivo

(2015) YAPING WANG et al.   Molecular Medicine Reports

Daily Variation in Global and Local DNA Methylation in Mouse Livers

(2015) Lin Xia et al.   PLoS One

Circadian gene variants in cancer

(2014) Nicole M. Kettner et al.   ANNALS OF MEDICINE

Sensing core histone phosphorylation — A matter of perfect timing

(2014) Anna Sawicka et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Deregulated Expression of the Per1 and Per2 in Human Gliomas

(2014) He-chun Xia et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

The circadian clock and cell cycle: interconnected biological circuits

(2013) Selma Masri et al.   CURRENT OPINION IN CELL BIOLOGY

Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing

(2013) R. Laranjeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian rhythms and tumor growth

(2012) Michael W. Greene   CANCER LETTERS

Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit

(2012) Wenyu Luo et al.   CELL

Connecting Threads: Epigenetics and Metabolism

(2012) Sayako Katada et al.   CELL

The circadian clock geneBMAL1is a novel therapeutic target for malignant pleural mesothelioma

(2012) Momen Elshazley et al.   INTERNATIONAL JOURNAL OF CANCER

Light Acts on the Zebrafish Circadian Clock to Suppress Rhythmic Mitosis and Cell Proliferation

(2012) T. Katherine Tamai et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian Gene Expression and Clinicopathologic Correlates in Pancreatic Cancer

(2012) Daniel Relles et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Trials with ‘epigenetic’ drugs: An update

(2012) Angela Nebbioso et al.   Molecular Oncology

NONO couples the circadian clock to the cell cycle

(2012) E. Kowalska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines

(2012) R. Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer

(2011) Feng Zhou et al.   CANCER

Altered Expression of Circadian Clock Genes in Human Chronic Myeloid Leukemia

(2011) Ming-Yu Yang et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night

(2011) David E. Blask et al.   JOURNAL OF PINEAL RESEARCH

A Molecular Mechanism for Circadian Clock Negative Feedback

(2011) H. A. Duong et al.   SCIENCE

Circadian Timing in Cancer Treatments

(2010) Francis Lévi et al.   Annual Review of Pharmacology and Toxicology

The role of polymorphisms in circadian pathway genes in breast tumorigenesis

(2010) Hongji Dai et al.   BREAST CANCER RESEARCH AND TREATMENT

CLOCK in Breast Tumorigenesis: Genetic, Epigenetic, and Transcriptional Profiling Analyses

(2010) A. E. Hoffman et al.   CANCER RESEARCH

Elevated ATPase Activity of KaiC Applies a Circadian Checkpoint on Cell Division in Synechococcus elongatus

(2010) Guogang Dong et al.   CELL

Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors

(2010) Cliona Grant et al.   Expert Review of Anticancer Therapy

Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock

(2010) Y. Lee et al.   JOURNAL OF CELL SCIENCE

Plasticity and specificity of the circadian epigenome

(2010) Selma Masri et al.   NATURE NEUROSCIENCE

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

(2010) Sayako Katada et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice

(2010) Susie Lee et al.   PLoS One

Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts

(2009) Anne Monks et al.   ANTI-CANCER DRUGS

Testing the Circadian Gene Hypothesis in Prostate Cancer: A Population-Based Case-Control Study

(2009) Y. Zhu et al.   CANCER RESEARCH

Epigenetic Inactivation of the Circadian Clock Gene BMAL1 in Hematologic Malignancies

(2009) H. Taniguchi et al.   CANCER RESEARCH

A Role for the Clock Gene Per1 in Prostate Cancer

(2009) Q. Cao et al.   CANCER RESEARCH

The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors

(2009) Astrid Spannhoff et al.   ChemMedChem

Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia

(2009) Lewin Eisele et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Cryptochrome-1 expression: a new prognostic marker in B-cell chronic lymphocytic leukemia

(2009) E. J. Lewintre et al.   HAEMATOLOGICA

Per2 Inhibits K562 Leukemia Cell Growth In Vitro and In Vivo Through Cell Cycle Arrest and Apoptosis Induction

(2009) Cheng-ming Sun et al.   PATHOLOGY & ONCOLOGY RESEARCH

A Large Scale shRNA Barcode Screen Identifies the Circadian Clock Component ARNTL as Putative Regulator of the p53 Tumor Suppressor Pathway

(2009) Jasper Mullenders et al.   PLoS One

Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura: The Emerging Gene Portrait of the Mesothelioma Phenotype

(2009) Oluf Dimitri Røe et al.   PLoS One

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

Overexpression of Aurora B is associated with poor prognosis in epithelial ovarian cancer patients

(2009) Yi-Jen Chen et al.   VIRCHOWS ARCHIV

Disturbance of circadian gene expression in breast cancer

(2009) Shou-Jen Kuo et al.   VIRCHOWS ARCHIV

Clinicopathological significance of circadian rhythm-related gene expression levels in patients with epithelial ovarian cancer

(2008) Hideki Tokunaga et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm

(2008) Xiaoming Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy

(2008) S. Tanaka et al.   BRITISH JOURNAL OF SURGERY

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

Period 2 Mutation Accelerates ApcMin/+ Tumorigenesis

(2008) P. A. Wood et al.   MOLECULAR CANCER RESEARCH

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology

(2008) Theresa Alenghat et al.   NATURE