Synthesis of β‐amino acid derivatives and their inhibitory profiles against some metabolic enzymes

Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H -chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials

(2019) Abel Maharramov et al.   ARCHIV DER PHARMAZIE

Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties

(2019) Emre Güzel et al.   ARCHIV DER PHARMAZIE

Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase, and α-glycosidase enzymes

(2019) Ercan Bursal et al.   JOURNAL OF FOOD BIOCHEMISTRY

Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives

(2019) Fikret Turkan et al.   ARCHIV DER PHARMAZIE

Synthesis of Oxazolidinone from Enantiomerically Enriched Allylic Alcohols and Determination of Their Molecular Docking and Biologic Activities

(2019) Ufuk Atmaca et al.   BIOORGANIC CHEMISTRY

Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases

(2019) Burak Kuzu et al.   BIOORGANIC CHEMISTRY

Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Fikret Turkan et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester

(2019) Murat Boztas et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors

(2019) Serdar Burmaoglu et al.   BIOORGANIC CHEMISTRY

Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes

(2019) Kaan Kucukoglu et al.   BIOORGANIC CHEMISTRY

Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

(2019) Hayriye Genç Bilgiçli et al.   BIOORGANIC CHEMISTRY

Synthesis and characterization of novel bromophenols: Determination of their anticholinergic, antidiabetic and antioxidant activities

(2019) Necla Öztaşkın et al.   BIOORGANIC CHEMISTRY

New phenolic Mannich bases with piperazines and their bioactivities

(2019) Halise Inci Gul et al.   BIOORGANIC CHEMISTRY

The green synthesis and molecular docking of novel N-substituted rhodanines as effective inhibitors for carbonic anhydrase and acetylcholinesterase enzymes

(2019) Sinan Bayindir et al.   BIOORGANIC CHEMISTRY

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

(2019) Fatoş Erdemir et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy

(2018) Alessio Nocentini et al.   BIOORGANIC CHEMISTRY

Sulfonamide inhibitors: a patent review 2013-present

(2018) İlhami Gulçin et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties

(2018) Parham Taslimi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Antioxidant and anticholinergic properties of olivetol

(2018) Parham Taslimi et al.   JOURNAL OF FOOD BIOCHEMISTRY

The effects of some antibiotics from cephalosporin groups on the acetylcholinesterase and butyrylcholinesterase enzymes activities in different tissues of rats

(2018) Fikret Türkan et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Novel Benzylic Substituted Imidazolinium, Tetrahydropyrimidinium and Tetrahydrodiazepinium Salts: Potent Carbonic Anhydrase and Acetylcholinesterase Inhibitors

(2018) Beyhan Yiğit et al.   ChemistrySelect

Synthesis of novel sulfamides incorporating phenethylamines and determination of their inhibition profiles against some metabolic enzymes

(2018) Kadir Aksu et al.   ARCHIV DER PHARMAZIE

Some pyrazoles derivatives: Potent carbonic anhydrase, α-glycosidase, and cholinesterase enzymes inhibitors

(2018) Fikret Turkan et al.   ARCHIV DER PHARMAZIE

Novel sulfamate derivatives of menthol: Synthesis, characterization, and cholinesterases and carbonic anhydrase enzymes inhibition properties

(2018) Shahla Daryadel et al.   ARCHIV DER PHARMAZIE

Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials

(2018) Mustafa Zengin et al.   BIOORGANIC CHEMISTRY

New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones

(2018) Mehtap Tugrak et al.   BIOORGANIC CHEMISTRY

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia

(2018) Parham Taslimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes

(2018) İlhami Gulçin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with N -salicyloil-N ′-maleoil-hydrazine as anticholinergic and antidiabetic agents

(2018) Gulnar Gondolova et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis, characterization, crystal structure, electrochemical studies and biological evaluation of metal complexes with thiosemicarbazone of glyoxylic acid

(2018) Mansura Huseynova et al.   POLYHEDRON

Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract

(2018) N. Eruygur et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes

(2018) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

Synthesis, characterization, antioxidant, antidiabetic, anticholinergic, and antiepileptic properties of novel N‐substituted tetrahydropyrimidines based on phenylthiourea

(2018) Gunel Maharramova et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach

(2018) Cuneyt Caglayan et al.   JOURNAL OF FOOD BIOCHEMISTRY

Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors

(2018) Salih Ökten et al.   JOURNAL OF MOLECULAR STRUCTURE

Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties

(2018) Aydın Aktaş et al.   POLYHEDRON

Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

(2018) Dilan Ozmen Ozgun et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes

(2018) Abdullah Biçer et al.   BIOORGANIC CHEMISTRY

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

(2018) Cetin Bayrak et al.   BIOORGANIC CHEMISTRY

Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones

(2015) Akın Akıncıoğlu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II

(2015) Alper Yıldırım et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives

(2015) Necla Öztaşkın et al.   BIOORGANIC CHEMISTRY

Purification and Characterization of Polyphenol Oxidase from Hemşin Apple (Malus communisL.)

(2015) Bahar Aydin et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)

(2015) Andrea Scozzafava et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Natural Product Primary Sulfonamides and Primary Sulfamates

(2015) Prashant Mujumdar et al.   JOURNAL OF NATURAL PRODUCTS

Carbonic anhydrase inhibitory properties of novel benzylsulfamides using molecular modeling and experimental studies

(2014) Süleyman Göksu et al.   BIOORGANIC CHEMISTRY

Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II

(2014) Stefan Schwarz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sulfonamides and their isosters as carbonic anhydrase inhibitors

(2014) Fabrizio Carta et al.   Future Medicinal Chemistry

Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates

(2014) Hülya Göçer et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII)

(2014) Andrea Scozzafava et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane Moieties

(2014) Murat Boztaş et al.   JOURNAL OF MEDICINAL CHEMISTRY

Capsaicin: A Potent Inhibitor of Carbonic Anhydrase Isoenzymes

(2014) Betul Arabaci et al.   MOLECULES

Rapid screening and identification ofα-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR

(2012) Yi Tao et al.   BIOMEDICAL CHROMATOGRAPHY

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds

(2011) Sevim Beyza Öztürk Sarikaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds

(2011) Murat Şentürk et al.   Chemical Biology & Drug Design

Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I–XIV with a series of natural product polyphenols and phenolic acids

(2010) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I–XV

(2010) Alessio Innocenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic anhydrase inhibitors

(2010) Claudiu T. Supuran   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic Anhydrase Inhibitors: Inhibition of Human Erythrocyte Isozymes I and II with a Series of Phenolic Acids

(2010) S. Beyza Öztürk Sarıkaya et al.   Chemical Biology & Drug Design

Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols

(2009) Murat Şentürk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I–XIV

(2009) T. Abdülkadir Coban et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY