In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development

A novel myelin protein zero transgenic zebrafish designed for rapid readout of in vivo myelination

(2019) Marnie A. Preston et al.   GLIA

Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant

(2019) Elvira Diamantopoulou et al.   eLife

Fungicidal PMMA-Undecylenic Acid Composites

(2018) Milica Petrović et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin

(2018) Sarah D. Ackerman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Differentiation in Response to Lysolecithin-Induced Demyelination

(2018) Changqing Lu et al.   Scientific Reports

An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination

(2018) Jason J Early et al.   eLife

In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and α1 receptors

(2018) Hui Li Heng et al.   Chemical Biology & Drug Design

Drug discovery for remyelination and treatment of MS

(2017) Katy L. H. Cole et al.   GLIA

Activation of Adhesion G Protein-coupled Receptors

(2017) Lilian M. Demberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The scales and tales of myelination: using zebrafish and mouse to study myelinating glia

(2016) Sarah D. Ackerman et al.   BRAIN RESEARCH

G-protein coupled receptors: advances in simulation and drug discovery

(2016) Yinglong Miao et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Antifungal effects of undecylenic acid on the biofilm formation of Candida albicans

(2016) Dongmei Shi et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair

(2016) Amit Mogha et al.   JOURNAL OF NEUROSCIENCE

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination

(2016) Feng Mei et al.   JOURNAL OF NEUROSCIENCE

Functional and structural characterization of axonal opioid receptors as targets for analgesia

(2016) Egle M Mambretti et al.   Molecular Pain

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

(2016) Alexander Küffer et al.   NATURE

G Protein-Coupled Receptors in Myelinating Glia

(2016) Amit Mogha et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

New paradigms in GPCR drug discovery

(2015) Kenneth A. Jacobson   BIOCHEMICAL PHARMACOLOGY

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

(2015) Breanne L Harty et al.   BMC GENOMICS

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development

(2015) Stefanie Giera et al.   Nature Communications

The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA

(2015) Sarah D. Ackerman et al.   Nature Communications

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

(2014) Ines Liebscher et al.   Annals of the New York Academy of Sciences

Zebrafish as a model to investigate CNS myelination

(2014) Marnie A. Preston et al.   GLIA

Investigation of the effect of telmisartan on experimentally induced peripheral nerve injury in rats

(2014) Tugba Nurcan Yuksel et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

Glial Cell Development and Function in Zebrafish

(2014) David A. Lyons et al.   Cold Spring Harbor Perspectives in Biology

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone

(2014) Cody J. Smith et al.   PLOS BIOLOGY

Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin

(2013) T. D. Glenn et al.   DEVELOPMENT

Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation

(2013) A. Mogha et al.   JOURNAL OF NEUROSCIENCE

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via G s/G q-mediated protein kinases A/C

(2013) D. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent

(2013) C. Patra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding Signaling and Function of the Orphan G Protein-Coupled Receptor GPR17 with a Small-Molecule Agonist

(2013) S. Hennen et al.   Science Signaling

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Dissecting signaling and functions of adhesion G protein-coupled receptors

(2012) Demet Araç et al.   Annals of the New York Academy of Sciences

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Signaling property study of adhesion G-protein-coupled receptors

(2012) Jamila Gupte et al.   FEBS LETTERS

Rac1 Controls Schwann Cell Myelination through cAMP and NF2/merlin

(2012) L. Guo et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

(2012) Simone Prömel et al.   Cell Reports

Individual axons regulate the myelinating potential of single oligodendrocytes in vivo

(2011) R. G. Almeida et al.   DEVELOPMENT

Gpr126 is essential for peripheral nerve development and myelination in mammals

(2011) K. R. Monk et al.   DEVELOPMENT

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

(2010) Clare E. Buckley et al.   NEUROPHARMACOLOGY

Transcriptional Silencing and Reactivation in Transgenic Zebrafish

(2009) M. G. Goll et al.   GENETICS

A Selective Glial Barrier at Motor Axon Exit Points Prevents Oligodendrocyte Migration from the Spinal Cord

(2009) S. Kucenas et al.   JOURNAL OF NEUROSCIENCE

A G Protein-Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

(2009) K. R. Monk et al.   SCIENCE

Zebrafish myelination: a transparent model for remyelination?

(2008) C. E. Buckley et al.   Disease Models & Mechanisms

Development of the Schwann cell lineage: From the neural crest to the myelinated nerve

(2008) Ashwin Woodhoo et al.   GLIA

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols