Article
Nanoscience & Nanotechnology
Yuxiang Xue, Xinyao Ma, Xue Feng, Sam Roberts, Guangyu Zhu, Yi Huang, Xianfeng Fan, Jun Fan, Xianfeng Chen
Summary: Gold nanostructures, especially gold nanobipyramids, have gained significant attention due to their unique physical and optical properties. However, synthesizing and purifying homogeneous gold nanobipyramids is a challenging task.
ACS APPLIED NANO MATERIALS
(2023)
Article
Biochemical Research Methods
Min Liu, Xiaojuan Fu, Mengjie Lu, Jijian Liu, Huihui Xie, Peng Wei, Weidong Zhang, Yahong Xie, Ying Qi
Summary: The presence of IO3- can etch gold nanobipyramids (Au NBPs) and detect iodine (I-) in kelp. By measuring the blue shift of the LSPR longitudinal peak and the color change of the colloid, the concentration of I- can be quantitatively determined.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Chemistry, Analytical
Guojun Weng, Xun Shen, Jianjun Li, Jingyuan Wang, Jian Zhu, Junwu Zhao
Summary: This study proposes a multi-colorimetric ELISA for CRP detection based on the etching of Ag-coated Au nanobipyramids. The results show that the thickness of the coated silver shell plays a key role in the color change and sensitivity of the etched nanobipyramids.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu
Summary: A novel growth system using HCl-NADH-AA mediated gold nanobipyramids was developed, enabling the simultaneous screening and detection of five sulfonamide drugs with two multicolor signal channels.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Xianqiang Song, Xin Chen, Zhaoxiong Liang, Dan Xu, Yong Liang
Summary: This study developed a sensor platform based on gold nanobipyramids@silver nanorods for the quantitative, visual, and sensitive detection of Cr3+ ions in aqueous solutions. The method relies on the absorbance change of the nanorods induced by Cr3+ and can achieve a detection limit of 8.7 nM using a UV-vis spectrophotometer-based colorimetric detection method. The sensor shows high sensitivity, selectivity, and performance, making it useful for on-site quantitative detection of Cr3+ ions in water samples.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Daowei Liang, Yiwen Wang, Lanrui Ma, Yanlin Liu, Ruijie Fu, Haoran Liu, Yilin Peng, Yaohai Zhang, Chengqiu Wang, Bining Jiao, Yue He
Summary: In this study, a method for controlling the shape of gold nanobipyramids using thiocholine is proposed, and it is applied to construct a plasmonic colorimetric sensor for detecting organophosphorus pesticides. The method shows simple operation and high sensitivity, and has great potential for monitoring organophosphorus pesticides in agricultural products.
ACS APPLIED NANO MATERIALS
(2022)
Article
Food Science & Technology
Rui Guo, Yue Ji, Jinnan Chen, Jin Ye, Baoxia Ni, Li Li, Yongtan Yang
Summary: A multicolor visual method based on a magnetic immunoassay and enzyme-induced gold nanobipyramids etching was developed for the detection of deoxynivalenol (DON). The method showed a linear relationship between the shift of local surface plasmon resonance (LSPR) and the DON concentration. The recovery for naturally contaminated wheat and maize was satisfactory, and the proposed method has the potential for on-site rapid screening of mycotoxins in grain. However, there is a need for a breakthrough in the simultaneous detection of multiple mycotoxins using the current multicolor visual method.
Article
Chemistry, Analytical
Qin Luo, Mengjian Tian, Fang Luo, Min Zhao, Cuiying Lin, Bin Qiu, Jian Wang, Zhenyu Lin
Summary: In this study, a novel multicolor sensor for trypsin detection has been developed based on the regulation of peroxidase activity of BSA-Au NCs. By hydrolyzing BSA ligands on the surface of BSA-Au NCs, trypsin exposes more catalytic active sites of BSA-Au NCs, enhancing their peroxidase activity, resulting in the generation of more TMB+. Under acidic conditions, TMB+ effectively etches Au NBPs, changing their aspect ratio and causing a blue shift in the UV-vis spectra.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Qin Luo, Yu Chen, Lifen Chen, Zhonghui Chen, Fang Luo, Jian Wang, Cuiying Lin, Bin Qiu, Longhua Guo, Zhenyu Lin
Summary: A multicolor sensor based on the inhibition of peroxidase activity and color change caused by etching of gold nanobipyramids was constructed for Hg2+ detection. The sensor can achieve semi-quantitative detection using the multicolor changes of the gold nanobipyramids and quantitative sensing by measuring the UV-vis peak shift. The linear response range is 1.0 nM-10 μM, and the detection limit is 0.28 nM.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Hongshuai Zhu, Chuanhe Liu, Xinxin Liu, Zhu Quan, Weipeng Liu, Yingju Liu
Summary: A multi-colorimetric immunosensor based on the mimetic enzyme etching of gold nanobipyramids was established to detect ochratoxin A. The method showed high sensitivity and specificity, indicating its potential for OTA detection in real samples.
Article
Chemistry, Analytical
Eslam Hafez, Byeong-Seok Moon, Samy M. Shaban, Do-Gi Pyun, Dong-Hwan Kim
Summary: A colorimetric biosensor for ALP assay has been developed based on ALP affinity to dephosphorylate glucose phosphate into glucose, which provides a multicolor response with a high sensitivity and selectivity for point-of-care diagnosis.
Article
Chemistry, Analytical
Cong Zheng, Da Wu, Tao Wang, Jianhong Xiao, Li Yu
Summary: This study developed a novel colorimetric method for detecting hydrogen peroxide (H2O2) and glucose in sodium chloride solutions, based on gold nanoparticles, single-stranded DNA, and ceria nanoparticles. The method can detect the target substances by observing the color change of the aqueous solution, providing a potential avenue for quantitative detection in clinical diagnostics.
Article
Chemistry, Analytical
Qin Luo, Mengjian Tian, Fang Luo, Min Zhao, Cuiying Lin, Bin Qiu, Jian Wang, Zhenyu Lin
Summary: This study established an innovative multicolor sensor for trypsin detection, based on the regulation of the peroxidase activity of BSA-Au NCs and efficient etching of Au NBPs. The designed sensor has a linear relationship with the logarithm of trypsin concentration, with a detection limit of 0.045 μg/mL. It has been successfully applied to analyze trypsin concentration in human serum samples from healthy individuals and pancreatitis patients.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Varsha UshaVipinachandran, Sathish Rajendran, Haydar Ali, Indhumathi Ashokan, Susanta Kumar Bhunia
Summary: As the usage of antibiotics and vitamin tablets becomes more widespread, a rapid colorimetric sensor has been developed for the selective recognition of neomycin and thiamine. The sensor utilizes citrate capped silver nanoparticles and exhibits excellent performance for the determination of these drugs at low concentrations. This sensor shows prolonged selectivity even in the presence of interfering drug mixtures and in real sample analysis.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Food Science & Technology
Shengnan Wei, Zhenyue Su, Xiangong Bu, Xuening Shi, Bo Pang, Liang Zhang, Juan Li, Chao Zhao
Summary: A colorimetric assay aptasensor for the detection of Salmonella typhimurium was developed using gold nanoparticles embedded spherical covalent organic framework with peroxidase-like activity and the affinity and specificity of S. typhimurium-aptamer. The aptasensor showed a low detection limit and good recovery rates, and can be combined with a smartphone-based image analysis system for point-of-care testing.
NPJ SCIENCE OF FOOD
(2022)
Article
Materials Science, Multidisciplinary
Nianzu Liu, Yihui Ma, Zhenying Xu, Yingshu Guo, Xiliang Luo
Summary: We report a PANI-HA hydrogel that combines rigid conducting polymer with flexible HA. The supramolecular assembly of PANI and HA via boronic acid bonds yields PANI-HA hydrogel with unique microstructure, electrical conductivity and hydrophilicity, showing excellent supercapacitor performance and electrochemical sensing for IgG. The PANI-HA hydrogel-based electrode exhibits high specific capacitance (369 F g(-1)) and good cycling stability (85% capacity retention after 1000 charge-discharge cycles). It can also be used as an electrochemical biosensor for IgG detection with good sensitivity, wide detection range, and low detection limit.
JOURNAL OF MATERIALS SCIENCE
(2023)
Editorial Material
Chemistry, Analytical
Xiliang Luo
Article
Chemistry, Multidisciplinary
Sai Zhang, Ping Chen, Yu Fan, Yan Zhao, Wenlong Yang, Hongtao Gao, Xiliang Luo
Summary: This study successfully synthesized amorphous and crystalline NiS2 nanospheres using a simple method and found that the amorphous structure of NiS2 catalyst has superior electrochemical activity for methanol oxidation reaction compared to the crystalline counterpart.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Lei Zhang, Han Liu, Qianyao Du, Guoqiang Zhang, Shanhui Zhu, Zhongtao Wu, Xiliang Luo
Summary: Photoresponsive phase change materials have the ability to store and release both photon and heat energy. By designing azobenzene surfactants at the molecular level, it is possible to achieve high gravimetric energy density and enhance molar isomerization enthalpy.
Article
Chemistry, Analytical
Xiqin Yang, Ping Chen, Xi Zhang, Hao Zhou, Zhen Song, Wenlong Yang, Xiliang Luo
Summary: A simple tactic for electrochemical determination of HER2, a typical biomarker for breast cancer, was developed through the construction of a low fouling sensing interface functionalized with PEG and peptide. The biosensor exhibited strong antifouling performances in complex biofluids due to the combined effect of PEG and peptide, and it had an ultralow limit of detection and a wide linear range for HER2 assay. The combination of PEG and peptide provided an effective strategy for the development of low fouling sensing platforms in complex biotic environments.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiao-Long Zhang, Sha-Sha Li, Yi-Jia Liu, Wei-Wei Liu, Ling-Qi Kong, Ya-Qin Chai, Xi-Liang Luo, Ruo Yuan
Summary: An ingenious three-dimensional DNA walker with high walking efficiency is developed by limiting the reaction space, providing a rapid and sensitive detection method for miRNA. Compared to traditional DNA walkers, this immobilized DNA walker shows improved kinetic and thermodynamic favorability, resulting in faster reaction speed and higher walking efficiency. By utilizing this walker, a sensitive sensing platform for rapid miRNA-21 detection is constructed with a limit of detection of 19.8 aM, allowing for highly sensitive biomarker detection in cancer cell lysates.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Yanxin Li, Shuju Zhao, Zhenying Xu, Xiujuan Qiao, Mingxuan Li, Youke Li, Xiliang Luo
Summary: A non-fouling electrochemical biosensor was constructed using antifouling peptides and electroneutral PNA as the recognizing probe for SARS-CoV-2 viral RNA. The biosensor exhibited remarkable sensitivity with a broad linear range (1.0 fM -1.0 nM) and a low detection limit of 0.38 fM. This study provided a new strategy for developing non-fouling sensing systems capable of detecting trace disease biomarkers in complex biological media.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Shuju Zhao, Zhen Song, Tao Liu, Xin Wang, Yanxin Li, Yaqun Xu, Hao Wang, Yumin Wu, Xiliang Luo
Summary: Zwitterionic peptides with strong water binding ability have been designed to construct antifouling biosensors with enhanced stability in complex biological fluids. The designed peptides demonstrated much stronger antifouling capability and significantly enhanced stability in human serum and blood. Furthermore, the biosensor integrating the designed antifouling peptide with CEA aptamer exhibited a great sensitivity for detecting CEA protein, making it promising for practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Nianzu Liu, Ruoxing Wang, Shengjie Gao, Ruifang Zhang, Fengru Fan, Yihui Ma, Xiliang Luo, Dong Ding, Wenzhuo Wu
Summary: Leveraging mechanically-induced piezoelectric polarization, piezocatalysis emerges as a viable mechanism for enhancing catalytic processes. Nanostructured, catalytically active, rationally designed piezo-electric semiconductors can achieve high-performance catalysts for various applications using cost-effective electrocatalytic pathways, such as mechanical stimuli. The facile synthesis of high-quality ZnO nanostructures enables low-cost, scalable manufacture and direct integration into electrocatalysts for enhanced performance.
Article
Chemistry, Analytical
Yaqun Xu, Xiujuan Qiao, Zhi-Ling Song, Gao-Chao Fan, Xiliang Luo
Summary: A robust photoelectrochemical (PEC) biosensor capable of accurate detection in human serum was developed by integrating a new engineered branching peptide (EBP) into a synergetic dual-photoelectrode system. The biosensor exhibited high sensitivity, specificity, and anti-interference properties.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Fu-Hui Lyu, Chen-Chen Li, Yue Li, Lin Cui, Xi-Liang Luo
Summary: Metal-organic gels (MOGs) are gel materials formed by bridging metal ions and organic ligands via non covalent interactions. They have advantages such as easy preparation, large specific surface area, tunable structure, and abundant metal sites, making them widely used in sensing, analysis, catalysis, adsorption, energy storage and electrochromic devices. This paper reviews the progress in the research and application of MOGs in these fields, and discusses the challenges, future trends and application prospects.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: A DNA sensing platform with endogenous stimuli-responsive and ultrasensitive characteristics, incorporating a logic gate biocomputation, has been developed for precise cell subtype identification in disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rui Han, Wenjie Hou, Yang Li, Min Chen, Caifeng Ding, Xiliang Luo
Summary: A sensitive electrochemical biosensor based on a self-designed cyclic peptide is capable of detecting the RBD antigen in human blood. The cyclic peptide possesses excellent antifouling properties and strong anti-enzymatic hydrolysis ability, making the biosensor stable and reliable for COVID-19 antigen testing.
SENSORS & DIAGNOSTICS
(2023)
Article
Biophysics
Ze Hu, Hao Wang, Huimin Chen, Gao-Chao Fan, Xiliang Luo
Summary: In this study, an ingenious approach of target-triggered cascade signal amplification in porous anodic aluminum oxide nanochannels was developed for ultrasensitive photoelectrochemical DNA bioanalysis. The innovative nanochannels PEC strategy launched a novel detecting platform for trace levels of DNA, providing a potential inspiration for other smart nanochannels PEC bioassays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)