LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation

First-in-human phase I study of JPH203, L-type amino acids transporter 1 inhibitor, in patients with advanced solid tumors.

(2018) Naohiro Okano et al.   JOURNAL OF CLINICAL ONCOLOGY

The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies

(2017) Patrick M. Brunner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Metabolic pathways in T cell activation and lineage differentiation

(2016) Luís Almeida et al.   SEMINARS IN IMMUNOLOGY

Cyclin-Dependent Kinases as Coregulators of Inflammatory Gene Expression

(2016) M. Lienhard Schmitz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells

(2013) K. Hayashi et al.   JOURNAL OF IMMUNOLOGY

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

(2013) Linda V Sinclair et al.   NATURE IMMUNOLOGY

Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4

(2011) O. Kaminuma et al.   CLINICAL AND EXPERIMENTAL ALLERGY