Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity

Published 2015 View Full Article

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Title
Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity
Authors
Keywords
RIP2, RIPK2, RICK, CARD3, CARDIAK, X-ray cocrystal structure, Kinase structure, Kinase inhibitor, Structure-based drug design, Inhibitor selectivity
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 23, Issue 21, Pages 7000-7006
Publisher
Elsevier BV
Online
2015-09-26
DOI
10.1016/j.bmc.2015.09.038

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