Article
Oncology
Yuan Zhou, Changming Lin, Lian Zhu, Rentao Zhang, Lei Cheng, Yuanyuan Chang
Summary: This study established predictive models and a scoring system to predict the survival rate of prostate cancer patients. These tools can help clinicians individually assess the survival status of patients and contribute to clinical decisions.
Article
Medicine, General & Internal
Niuniu Hou, Jun Yi, Zhe Wang, Lu Yang, Ying Wu, Meiling Huang, Guangdong Hou, Rui Ling
Summary: This study aimed to identify independent prognostic factors in bone metastatic breast cancer (BMBC) and developed a prognostic nomogram to accurately predict survival. Factors such as marital status, race, age, tumor stage, grade, receptors, and metastasis sites were identified as independent prognostic factors for cancer-specific survival in BMBC. The nomogram showed good predictive performance and unbiased prediction in internal and external validation.
Article
Oncology
Qiujuan Huang, Tongyuan Qu, Lisha Qi, Changxu Liu, Yuhong Guo, Qianru Guo, Guangning Li, Yalei Wang, Wenshuai Zhang, Wei Zhao, Danyang Ren, Leina Sun, Shengguang Wang, Bin Meng, Baocun Sun, Bin Zhang, Wenjuan Ma, Wenfeng Cao
Summary: The study found that the immunoscore can be used as a new classification system for colorectal cancer and proposed a new immune-serum scoring system. These two scoring systems can better predict the prognosis of patients with lung adenocarcinoma, providing a new method for disease assessment.
CANCER BIOLOGY & MEDICINE
(2021)
Article
Oncology
Duorui Nie, Guihua Lai, Guilin An, Zhuojun Wu, Shujun Lei, Jing Li, Jianxiong Cao
Summary: This study found that PCT can significantly improve the prognosis of patients with mPC compared to pancreatic resection or chemotherapy alone. Factors such as age, gender, and tumor size can impact the survival benefits of PCT in patients with mPC.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Zhangheng Huang, Xin Zhou, Yuexin Tong, Lujian Zhu, Ruhan Zhao, Xiaohui Huang
Summary: Surgery for the primary tumor in breast cancer patients with bone metastases can significantly improve overall survival. Prognostic nomograms developed in this study can accurately assess long-term prognosis and assist clinicians in developing personalized treatment strategies.
Article
Oncology
Nan Wang, Wenqi Xi, Sheng Lu, Jinling Jiang, Chao Wang, Zhenglun Zhu, Chao Yan, Jing Liu, Jun Zhang
Summary: The study aimed to explore the prognostic value of preoperative inflammatory and nutritional biomarkers in stage III gastric cancer patients with adjuvant chemotherapy, and developed a novel scoring system called INPS. INPS was found to be an independent predictor of overall survival in stage III GC, and a nomogram based on INPS showed good predicting performance and was internally validated. Preoperative INPS may serve as a simple and potential model in risk stratification and guiding treatment strategies in clinical practice.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Ryon P. Graf, Ramez Eskander, Leo Brueggeman, Dwayne G. Stupack
Summary: This study showed that a CNV-based risk score is independent of and superior to current or future genomic biomarkers for ovarian cancer in predicting overall survival. The identified CNV regions were not strongly associated with canonical ovarian cancer biological pathways, indicating potential candidates for future mechanistic investigations. External validation of the CNV risk score, especially in conjunction with more extensive clinical features, could be pursued through existing FDA-approved assays.
Article
Oncology
Shurui Zhou, Yue Zhao, Yanzong Lu, Weiling Liang, Jianmin Ruan, Lijun Lin, Haoming Lin, Kaihong Huang
Summary: This study aimed to identify preoperative testing-based characteristics associated with enhanced prognosis and survival for cholangiocarcinoma patients, and to create a distinct nomogram to anticipate each patient's cancer-specific survival. A retrospective analysis was conducted on 197 CCA patients who underwent radical surgery, and a nomogram was created after identifying independent factors influencing patients' survival. The nomogram accurately predicted postoperative survival in an external validation cohort.
Article
Medicine, General & Internal
Wenwen Weng, Yanfei Chen, Yuwen Wang, Peiting Ying, Xiaoping Guo, Jinfei Ruan, Hua Song, Weiqun Xu, Jingying Zhang, Xiaojun Xu, Yongmin Tang
Summary: A clinical scoring system based on fusion genes was developed to predict outcomes in non-APL pediatric patients with AML. The nomogram score showed good calibration and concordance in predicting overall survival, with higher scores associated with worse outcomes. Internal validation confirmed the accuracy and applicability of the nomogram score, demonstrating good predictive performance.
FRONTIERS IN MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Chang-Zhi Chen, Jian-Hong Zhong, Ya-Peng Qi, Jie Zhang, Tao Huang, Liang Ma, Le-Qun Li, Tao Peng, Bang-De Xiang
Summary: A prognostic scoring system for hepatic resection in advanced HCC patients has been developed based on preoperative variables, which can help select patients who would benefit from hepatic resection. Patients classified as low risk using this system may experience better prognosis after hepatic resection.
BIOSCIENCE REPORTS
(2021)
Article
Medicine, General & Internal
Yunxing Luo, Xiwu He, Mingfei Yang, Chaonan Du, Xiaoqing Jin
Summary: A scoring system based on gray-white matter ratio was established to predict the prognostic risk factors of patients with acute epidural hematoma. Independent predictors related to the prognosis of AEDH were identified. The nomogram model showed higher predictive ability compared to other factors, providing an effective tool for predicting the prognosis of operated AEDH.
Article
Oncology
Wei Liu, Wei Zhang, Ye Xu, Yu-Hong Li, Bao-Cai Xing
Summary: This study aimed to develop a nomogram to predict progression-free survival (PFS) for patients with resectable colorectal liver metastases and suggested that high-risk patients may benefit from neoadjuvant chemotherapy. The nomogram showed good discriminative ability and accuracy in predicting PFS, with specific risk factors identified for liver-limited disease patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Fengshuo Xu, Luming Zhang, Zichen Wang, Didi Han, Chengzhuo Li, Shuai Zheng, Haiyan Yin, Jun Lyu
Summary: We established and validated a nomogram for predicting in-hospital death of LCEV patients, which showed good discriminative ability and calibration. The nomogram outperformed existing scoring systems and had good clinical value, but further external prospective validation is needed.
FRONTIERS IN MEDICINE
(2021)
Article
Oncology
Shaohui He, Runyi Jiang, Haitao Sun, Jian Yang, Chen Ye, Weibo Liu, Xinghai Yang, Xiaopan Cai, Jianru Xiao
Summary: This study examined the clinicopathological features and prognostic determinants for patients with unspecific malignant bone tumors (UMBTs) and developed a nomogram for predicting outcomes. The results showed that surgery improved outcomes for UMBT patients who received radiotherapy or chemotherapy.
Article
Surgery
Lingyu Han, Weixing Dai, Shaobo Mo, Wenqiang Xiang, Qingguo Li, Ye Xu, Guoxiang Cai, Renjie Wang
Summary: The study found that patients with metastatic colorectal cancer demonstrated a substantial increase in conditional survival over time. Factors affecting survival may change gradually, and nomograms based on survival time can accurately predict survival for patients with mCRC.
INTERNATIONAL JOURNAL OF SURGERY
(2021)