Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter

Folate-targeting annonaceous acetogenins nanosuspensions: significantly enhanced antitumor efficacy in HeLa tumor-bearing mice

(2018) Haowen Li et al.   DRUG DELIVERY

Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages

(2018) Sofia Raniolo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies

(2018) Zhenyi An et al.   ONCOGENE

Evaluation of intranasal delivery route of drug administration for brain targeting

(2018) Franciska Erdő et al.   BRAIN RESEARCH BULLETIN

Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells

(2017) Fatma Demir Duman et al.   Nanomedicine

Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer

(2016) Miriana Hijaz et al.   BMC CANCER

Folate-conjugated gold nanoparticle as a new nanoplatform for targeted cancer therapy

(2016) Hadi Samadian et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Combining Stimulus-Triggered Release and Active Targeting Strategies Improves Cytotoxicity of Cytochrome c Nanoparticles in Tumor Cells

(2016) Moraima Morales-Cruz et al.   MOLECULAR PHARMACEUTICS

Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo

(2016) James C. Evans et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanomaterials for early detection of cancer biomarker with special emphasis on gold nanoparticles in immunoassays/sensors

(2015) R. Viswambari Devi et al.   BIOSENSORS & BIOELECTRONICS

Polymeric nanoparticles for targeted treatment in oncology: current insights

(2015) Medha D Joshi et al.   International Journal of Nanomedicine

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

(2015) Andreas Wicki et al.   JOURNAL OF CONTROLLED RELEASE

Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway

(2015) Kimberleve Rolón-Reyes et al.   PLoS One

Targeted drug delivery via folate receptors in recurrent ovarian cancer: a review

(2014) Claudia Marchetti et al.   OncoTargets and Therapy

The Significance of Transferrin Receptors in Oncology: the Development of Functional Nano-based Drug Delivery Systems

(2014) Stephanie Tortorella et al.   Current Drug Delivery

Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles

(2014) Moraima Morales-Cruz et al.   JOURNAL OF NANOBIOTECHNOLOGY

Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells

(2013) Xiaoyan Wang et al.   BIOMACROMOLECULES

Expression of folate receptors in nasopharyngeal and laryngeal carcinoma and folate receptor-mediated endocytosis by molecular targeted nanomedicine

(2013) Xie et al.   International Journal of Nanomedicine

Selective accumulation of hematoporphyrin derivative in glioma through proton-coupled folate transporter SLC46A1

(2013) Tomoya Takada et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors

(2013) Rongbao Zhao et al.   MOLECULAR ASPECTS OF MEDICINE

Delivery of Chemically Glycosylated Cytochrome c Immobilized in Mesoporous Silica Nanoparticles Induces Apoptosis in HeLa Cancer Cells

(2013) Jessica Méndez et al.   MOLECULAR PHARMACEUTICS

The Many Spaces of uPAR: Delivery of Theranostic Agents and Nanobins to Multiple Tumor Compartments through a Single Target

(2013) Thomas V. O'Halloran et al.   Theranostics

Targeted Toxins for Glioblastoma Multiforme: Pre-Clinical Studies and Clinical Implementation

(2012) Marianela Candolfi et al.   Anti-Cancer Agents in Medicinal Chemistry

The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles

(2012) Sang Kyoon Kim et al.   BIOMATERIALS

Knockdown of AKT2 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to the anticancer drug VM-26 in U87 glioma cells

(2012) Yong Cui et al.   BRAIN RESEARCH

The human proton-coupled folate transporter

(2012) Sita Kugel Desmoulin et al.   CANCER BIOLOGY & THERAPY

Adaptive transport of folic acid across renal epithelia in folate-deficient rats

(2012) Nissar Ahmad Wani et al.   Journal of Physiological Sciences

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Conjugation of Functionalized SPIONs with Transferrin for Targeting and Imaging Brain Glial Tumors in Rat Model

(2012) Weili Jiang et al.   PLoS One

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

(2010) S. Mazzoleni et al.   CANCER RESEARCH

Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2

(2010) R. Hatakeyama et al.   MOLECULAR AND CELLULAR BIOLOGY

CytochromecEncapsulating Theranostic Nanoparticles: A Novel Bifunctional System for Targeted Delivery of Therapeutic Membrane-Impermeable Proteins to Tumors and Imaging of Cancer Therapy

(2010) Santimukul Santra et al.   MOLECULAR PHARMACEUTICS

Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

(2010) S. K. Desmoulin et al.   MOLECULAR PHARMACOLOGY

PI3K/PTEN/Akt pathway status affects the sensitivity of high-grade glioma cell cultures to the insulin-like growth factor-1 receptor inhibitor NVP-AEW541

(2010) Daniel Hägerstrand et al.   NEURO-ONCOLOGY

Glucose-induced Ubiquitylation and Endocytosis of the Yeast Jen1 Transporter

(2009) Sandra Paiva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arrestin-Mediated Endocytosis of Yeast Plasma Membrane Transporters

(2009) Elina Nikko et al.   TRAFFIC

Arrestin-Related Ubiquitin-Ligase Adaptors Regulate Endocytosis and Protein Turnover at the Cell Surface

(2008) Charles H. Lin et al.   CELL

Interleukin-13 Receptor  2, EphA2, and Fos-Related Antigen 1 as Molecular Denominators of High-Grade Astrocytomas and Specific Targets for Combinatorial Therapy

(2008) J. Wykosky et al.   CLINICAL CANCER RESEARCH

A Role for the Proton-coupled Folate Transporter (PCFT-SLC46A1) in Folate Receptor-mediated Endocytosis

(2008) Rongbao Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Clinical Course and Genetic Defect in the PCFT Gene in a 27-Year-Old Woman with Hereditary Folate Malabsorption

(2008) Sang Hee Min et al.   JOURNAL OF PEDIATRICS