IL7RA rs6897932 Polymorphism is Associated with Better CD4+ T-Cell Recovery in HIV Infected Patients Starting Combination Antiretroviral Therapy

Autoimmunity risk- and protection-associated IL7RA genetic variants differentially affect soluble and membrane IL-7Rα expression

(2018) Christian Lundtoft et al.   JOURNAL OF AUTOIMMUNITY

Gene variation in IL-7 receptor (IL-7R)α affects IL-7R response in CD4+ T cells in HIV-infected individuals

(2017) Hans Jakob Hartling et al.   Scientific Reports

Late presentation to HIV care despite good access to health services: current epidemiological trends and how to do better

(2016) KE Darling et al.   SWISS MEDICAL WEEKLY

IL7RApolymorphisms predict the CD4+ recovery in HIV patients on cART

(2015) María Guzmán-Fulgencio et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Polymorphism in interleukin-7 receptor α gene is associated with faster CD4+ T-cell recovery after initiation of combination antiretroviral therapy

(2014) Hans J. Hartling et al.   AIDS

Risk Factors and Outcomes for Late Presentation for HIV-Positive Persons in Europe: Results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE)

(2013) Amanda Mocroft et al.   PLOS MEDICINE

Poor CD4 response despite viral suppression is associated with increased non-AIDS-related mortality among HIV patients and their parents

(2012) Marie Helleberg et al.   AIDS

Identification of IL7RA Risk Alleles for Rapid Progression During HIV-1 Infection: A Comprehensive Study in the GRIV Cohort

(2012) Sophie Limou et al.   CURRENT HIV RESEARCH

Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients

(2012) K L Kreft et al.   GENES AND IMMUNITY

Antiretroviral Treatment of Adult HIV Infection

(2012) Melanie A. Thompson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients

(2011) Victor Appay et al.   AIDS

Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance

(2011) J. N. Hodge et al.   BLOOD

Immune reconstitution under antiretroviral therapy: the new challenge in HIV-1 infection

(2011) P. Corbeau et al.   BLOOD

Reduced Thymic Output Is a Major Mechanism of Immune Reconstitution Failure in HIV-Infected Patients After Long-term Antiretroviral Therapy

(2011) Taisheng Li et al.   CLINICAL INFECTIOUS DISEASES

The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART

(2011) R Rajasuriar et al.   GENES AND IMMUNITY

Very late initiation of HAART impairs treatment response at 48 and 96 weeks: results from a meta-analysis of randomized clinical trials

(2011) J. A. Perez-Molina et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

(2010) Marta Massanella et al.   AIDS

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

(2010) Eugènia Negredo et al.   CLINICAL INFECTIOUS DISEASES

Soluble IL-7R  (sCD127) Inhibits IL-7 Activity and Is Increased in HIV Infection

(2010) A. M. Crawley et al.   JOURNAL OF IMMUNOLOGY

Biological Determinants of Immune Reconstitution in HIV‐Infected Patients Receiving Antiretroviral Therapy: The Role of Interleukin 7 and Interleukin 7 Receptor α and Microbial Translocation

(2010) Reena Rajasuriar et al.   JOURNAL OF INFECTIOUS DISEASES

Incomplete Peripheral CD4+Cell Count Restoration in HIV‐Infected Patients Receiving Long‐Term Antiretroviral Treatment

(2009) Colleen F. Kelley et al.   CLINICAL INFECTIOUS DISEASES

Poor Initial CD4+ Recovery With Antiretroviral Therapy Prolongs Immune Depletion and Increases Risk for AIDS and Non-AIDS Diseases

(2009) Jason V Baker et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Modulating T-cell homeostasis with IL-7: preclinical and clinical studies

(2009) C. M. Capitini et al.   JOURNAL OF INTERNAL MEDICINE

Better CD4+ T Cell Recovery in Brazilian HIV-Infected Individuals Under HAART Due to Cumulative Carriage of SDF-1-3A, CCR2-V64I, CCR5- D32 and CCR5-Promoter 59029A/G Polymorphisms

(2008) Paula Rigato et al.   CURRENT HIV RESEARCH

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1–infected individuals

(2008) Sunil K Ahuja et al.   NATURE MEDICINE