Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo
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Title
Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo
Authors
Keywords
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Journal
Science Immunology
Volume 4, Issue 37, Pages eaaw6693
Publisher
American Association for the Advancement of Science (AAAS)
Online
2019-07-27
DOI
10.1126/sciimmunol.aaw6693
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Note: Only part of the references are listed.- Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation
- (2019) Eliza JR Peterson et al. Molecular Systems Biology
- Building a tuberculosis-free world: The Lancet Commission on tuberculosis
- (2019) Michael J A Reid et al. LANCET
- Growth ofMycobacterium tuberculosisin vivo segregates with host macrophage metabolism and ontogeny
- (2018) Lu Huang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
- (2018) Sara B. Cohen et al. Cell Host & Microbe
- Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis
- (2018) Krishna C. Chinta et al. Cell Reports
- Integrating Lung Physiology, Immunology, and Tuberculosis
- (2017) Jordi B. Torrelles et al. TRENDS IN MICROBIOLOGY
- The ins and outs of theMycobacterium tuberculosis-containing vacuole
- (2016) David G. Russell CELLULAR MICROBIOLOGY
- Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection
- (2016) Akihito Otsuki et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2 Modulates Host Defense duringStreptococcus pneumoniaePneumonia in Mice
- (2016) John C. Gomez et al. JOURNAL OF IMMUNOLOGY
- Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages duringMycobacterium tuberculosisInfection
- (2016) Caitlyn R. Scharn et al. JOURNAL OF IMMUNOLOGY
- HIF-1α Is an Essential Mediator of IFN-γ–Dependent Immunity toMycobacterium tuberculosis
- (2016) Jonathan Braverman et al. JOURNAL OF IMMUNOLOGY
- MiR-155–regulated molecular network orchestrates cell fate in the innate and adaptive immune response toMycobacterium tuberculosis
- (2016) Alissa C. Rothchild et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
- (2015) Robert O. Watson et al. Cell Host & Microbe
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
- (2015) Angela C. Collins et al. Cell Host & Microbe
- Sensing ofMycobacterium tuberculosisand consequences to both host and bacillus
- (2015) Chelsea E. Stamm et al. IMMUNOLOGICAL REVIEWS
- Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis
- (2015) Bruno B. Andrade et al. JOURNAL OF IMMUNOLOGY
- The development and function of lung-resident macrophages and dendritic cells
- (2015) Manfred Kopf et al. NATURE IMMUNOLOGY
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
- (2014) Yonit Lavin et al. CELL
- Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
- (2014) David Gosselin et al. CELL
- Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming
- (2014) Smita Srivastava et al. Cell Host & Microbe
- The Macrophage Paradox
- (2014) Jordan V. Price et al. IMMUNITY
- Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
- (2014) Clare L. Abram et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis
- (2014) Kevin B. Urdahl SEMINARS IN IMMUNOLOGY
- Marburgvirus Hijacks Nrf2-Dependent Pathway by Targeting Nrf2-Negative Regulator Keap1
- (2014) Audrey Page et al. Cell Reports
- The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway
- (2014) Megan R. Edwards et al. Cell Reports
- Respiratory risks from household air pollution in low and middle income countries
- (2014) Stephen B Gordon et al. Lancet Respiratory Medicine
- Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung
- (2013) Alexander V. Misharin et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Immune Response in Tuberculosis
- (2013) Anne O'Garra et al. Annual Review of Immunology
- A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection
- (2013) Marlène Brandes et al. CELL
- Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
- (2013) Martin Guilliams et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TPL-2-ERK1/2 Signaling Promotes Host Resistance against Intracellular Bacterial Infection by Negative Regulation of Type I IFN Production
- (2013) F. W. McNab et al. JOURNAL OF IMMUNOLOGY
- Modulation of oxidative stress as an anticancer strategy
- (2013) Chiara Gorrini et al. NATURE REVIEWS DRUG DISCOVERY
- Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages
- (2012) Paolo S. Manzanillo et al. Cell Host & Microbe
- Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice
- (2012) Janhavi Athale et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis
- (2012) L. Desvignes et al. JOURNAL OF IMMUNOLOGY
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Nrf2 Regulates Chronic Lung Inflammation and B-Cell Responses to NontypeableHaemophilus influenzae
- (2011) Amit A. Lugade et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Conditional Deletion ofNrf2in Airway Epithelium Exacerbates Acute Lung Injury and Impairs the Resolution of Inflammation
- (2011) Narsa M. Reddy et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Cigarette Smoke Increases Susceptibility to Tuberculosis—Evidence From In Vivo and In Vitro Models
- (2011) Shaobin Shang et al. JOURNAL OF INFECTIOUS DISEASES
- NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease
- (2011) A. Boutten et al. TRENDS IN MOLECULAR MEDICINE
- Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
- (2010) Bibhuti B. Mishra et al. CELLULAR MICROBIOLOGY
- Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
- (2010) Shahin Shafiani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Caspase-1 Independent IL-1 Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo
- (2010) K. D. Mayer-Barber et al. JOURNAL OF IMMUNOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Flexible low-cost system for small animal aerosol inhalation exposure to drugs, proteins, inflammatory agents, and infectious agents
- (2009) William G. Schroeder et al. BIOTECHNIQUES
- Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice
- (2009) N. M. Reddy et al. JOURNAL OF IMMUNOLOGY
- Modeling the immune rheostat of macrophages in the lung in response to infection
- (2009) J. Day et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease
- (2008) Hye-Youn Cho et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection
- (2008) Ingrid C. Koo et al. CELLULAR MICROBIOLOGY
- A critical function for CD200 in lung immune homeostasis and the severity of influenza infection
- (2008) Robert J Snelgrove et al. NATURE IMMUNOLOGY
- ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
- (2008) W. W. Reiley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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