Atypical complement receptor C5aR2 transports C5a to initiate neutrophil adhesion and inflammation

Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury–induced inflammation and fibrosis

(2018) Anja Thorenz et al.   KIDNEY INTERNATIONAL

Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis

(2018) Alessandro Angelini et al.   Nature Communications

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

(2018) Tamara Girbl et al.   IMMUNITY

Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury

(2017) Felix Poppelaars et al.   FASEB JOURNAL

Monitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse

(2017) Christian M. Karsten et al.   JOURNAL OF IMMUNOLOGY

Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2

(2016) Jackson LiangYao Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Atypical Chemokine Receptors and Their Roles in the Resolution of the Inflammatory Response

(2016) Raffaella Bonecchi et al.   Frontiers in Immunology

High Expression of C5L2 Correlates with High Proinflammatory Cytokine Expression in Advanced Human Atherosclerotic Plaques

(2014) Santosh Vijayan et al.   AMERICAN JOURNAL OF PATHOLOGY

DARC shuttles inflammatory chemokines across the blood–brain barrier during autoimmune central nervous system inflammation

(2014) Carsten Minten et al.   BRAIN

Leukocyte Migration into Inflamed Tissues

(2014) Sussan Nourshargh et al.   IMMUNITY

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

(2013) Markus Bosmann et al.   FASEB JOURNAL

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

(2012) Qi Cao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The biochemistry and biology of the atypical chemokine receptors

(2012) G.J. Graham et al.   IMMUNOLOGY LETTERS

Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and Fc R signaling

(2012) C. D. Sadik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Duffy antigen receptor for chemokines and its involvement in patterning and control of inflammatory chemokines

(2012) Igor Novitzky-Basso et al.   Frontiers in Immunology

Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines

(2010) Alexander Zarbock et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis

(2010) Richard C. Chou et al.   IMMUNITY

The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction

(2010) Claire E. Bamberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Critical Role for C5L2 in the Pathogenesis of Experimental Allergic Asthma

(2010) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation

(2010) D. Kreisel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines

(2009) Jörg Reutershan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation

(2009) Wei Cui et al.   MOLECULAR IMMUNOLOGY

Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene

(2009) David Reich et al.   PLoS Genetics

Genetic Inversion in Mast Cell-Deficient Wsh Mice Interrupts Corin and Manifests as Hematopoietic and Cardiac Aberrancy

(2008) Peter A. Nigrovic et al.   AMERICAN JOURNAL OF PATHOLOGY

The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity

(2008) Monika Pruenster et al.   NATURE IMMUNOLOGY

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE