Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory

The epigenetic control of stemness in CD8+T cell fate commitment

(2018) Luigia Pace et al.   SCIENCE

Effector CD8 T cells dedifferentiate into long-lived memory cells

(2017) Ben Youngblood et al.   NATURE

Heat stress promotes longevity in budding yeast by relaxing the confinement of age-promoting factors in the mother cell

(2017) Sandro Baldi et al.   eLife

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

CD8 + T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections

(2016) Bing He et al.   IMMUNITY

T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections

(2016) Daniel T. Utzschneider et al.   IMMUNITY

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

(2016) Katherine C. Verbist et al.   NATURE

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation

(2016) Kristen N Pollizzi et al.   NATURE IMMUNOLOGY

Polarization and asymmetry in T cell metabolism

(2016) Marcin M. Kamiński et al.   SEMINARS IN IMMUNOLOGY

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

(2016) Lianjun Zhang et al.   Cell Reports

Regulation of Asymmetric Division and CD8+T Lymphocyte Fate Specification by Protein Kinase Cζ and Protein Kinase Cλ/ι

(2015) Patrick J. Metz et al.   JOURNAL OF IMMUNOLOGY

Asymmetric Cell Division in T Lymphocyte Fate Diversification

(2015) Janilyn Arsenio et al.   TRENDS IN IMMUNOLOGY

Regulation of T cells by mTOR: the known knowns and the known unknowns

(2015) Kristen N. Pollizzi et al.   TRENDS IN IMMUNOLOGY

A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion

(2015) Amanda M. Butler et al.   Oncotarget

Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses

(2014) Janilyn Arsenio et al.   NATURE IMMUNOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

(2013) Linda V Sinclair et al.   NATURE IMMUNOLOGY

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

ICAM-1–dependent tuning of memory CD8 T-cell responses following acute infection

(2013) Maureen A. Cox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

(2012) Carolyn G. King et al.   IMMUNITY

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells

(2012) David K. Finlay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Asymmetric Memory T Cell Division in Response to Rechallenge

(2012) M. L. Ciocca et al.   JOURNAL OF IMMUNOLOGY

Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division

(2011) John T. Chang et al.   IMMUNITY

T-lymphocyte homeostasis and function in infant baboons: implications for transplantation

(2011) Dirk J. van der Windt et al.   TRANSPLANT INTERNATIONAL

One naive T cell, multiple fates in CD8+T cell differentiation

(2010) Carmen Gerlach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms

(2010) J. Oliaro et al.   JOURNAL OF IMMUNOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

(2009) Evgeny V. Berdyshev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

(2008) Alix Scholer et al.   IMMUNITY

Selective expansion of a subset of exhausted CD8 T cells by  PD-L1 blockade

(2008) S. D. Blackburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA