Journal
ARCHIVES OF VIROLOGY
Volume 161, Issue 12, Pages 3509-3514Publisher
SPRINGER WIEN
DOI: 10.1007/s00705-016-3032-3
Keywords
HSV-2; Antiviral; Plant extract; Ficus religiosa
Categories
Funding
- Silvana Legnani
Ask authors/readers for more resources
Ficus religiosa extracts have been used in traditional Indian medicine to treat sexually transmitted infections such as gonorrhea and genital ulcers. The aim of this study was to investigate the antiviral activity of F. religiosa extracts against herpes simplex virus type 2 (HSV-2), the main causative agent of genital ulcers and sores. Water and chloroform bark extracts were the most active against HSV-2, and also against an acyclovir-resistant strain. We demonstrate that the water extract has a direct virus-inactivating activity. By contrast, the chloroform extract inhibits viral attachment and entry and limits the production of viral progeny.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available